Следене
Brian D. Lehmann, PhD
Brian D. Lehmann, PhD
Research Associate Professor of Medicine, Vanderbilt University
Потвърден имейл адрес: vumc.org - Начална страница
Заглавие
Позовавания
Позовавания
Година
Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies
BD Lehmann, JA Bauer, X Chen, ME Sanders, AB Chakravarthy, Y Shyr, ...
The Journal of clinical investigation 121 (7), 2750-2767, 2011
57502011
Roles of the Raf/MEK/ERK pathway in cell growth, malignant transformation and drug resistance
JA McCubrey, LS Steelman, WH Chappell, SL Abrams, EWT Wong, ...
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1773 (8), 1263-1284, 2007
29122007
Refinement of triple-negative breast cancer molecular subtypes: implications for neoadjuvant chemotherapy selection
BD Lehmann, B Jovanović, XI Chen, MV Estrada, KN Johnson, Y Shyr, ...
PloS one 11 (6), e0157368, 2016
12662016
Differential response to neoadjuvant chemotherapy among 7 triple-negative breast cancer molecular subtypes
H Masuda, KA Baggerly, Y Wang, Y Zhang, AM Gonzalez-Angulo, ...
Clinical cancer research 19 (19), 5533-5540, 2013
8382013
Molecular profiling of the residual disease of triple-negative breast cancers after neoadjuvant chemotherapy identifies actionable therapeutic targets
JM Balko, JM Giltnane, K Wang, LJ Schwarz, CD Young, RS Cook, ...
Cancer discovery 4 (2), 232-245, 2014
5422014
Identification and use of biomarkers in treatment strategies for triple‐negative breast cancer subtypes
BD Lehmann, JA Pietenpol
The Journal of pathology 232 (2), 142-150, 2014
5232014
Senescence-associated exosome release from human prostate cancer cells
BD Lehmann, MS Paine, AM Brooks, JA McCubrey, RH Renegar, R Wang, ...
Cancer research 68 (19), 7864-7871, 2008
4932008
Subtyping of triple‐negative breast cancer: implications for therapy
VG Abramson, BD Lehmann, TJ Ballinger, JA Pietenpol
Cancer 121 (1), 8-16, 2015
4092015
New strategies for triple-negative breast cancer—deciphering the heterogeneity
IA Mayer, VG Abramson, BD Lehmann, JA Pietenpol
Clinical cancer research 20 (4), 782-790, 2014
3542014
PIK3CA mutations in androgen receptor-positive triple negative breast cancer confer sensitivity to the combination of PI3K and androgen receptor inhibitors
BD Lehmann, JA Bauer, JM Schafer, CS Pendleton, L Tang, KC Johnson, ...
Breast Cancer Research 16, 1-14, 2014
3532014
TNBCtype: a subtyping tool for triple-negative breast cancer
X Chen, J Li, WH Gray, BD Lehmann, JA Bauer, Y Shyr, JA Pietenpol
Cancer informatics 11, CIN. S9983, 2012
2682012
Suppression of PTEN function increases breast cancer chemotherapeutic drug resistance while conferring sensitivity to mTOR inhibitors
LS Steelman, PM Navolanic, ML Sokolosky, JR Taylor, BD Lehmann, ...
Oncogene 27 (29), 4086-4095, 2008
1982008
BRAF fusions define a distinct molecular subset of melanomas with potential sensitivity to MEK inhibition
KE Hutchinson, D Lipson, PJ Stephens, G Otto, BD Lehmann, PL Lyle, ...
Clinical Cancer Research 19 (24), 6696-6702, 2013
1922013
Identification of prognosis-relevant subgroups in patients with chemoresistant triple-negative breast cancer
KD Yu, R Zhu, M Zhan, AA Rodriguez, W Yang, S Wong, A Makris, ...
Clinical cancer research 19 (10), 2723-2733, 2013
1922013
Triple-negative breast cancer: molecular subtypes and new targets for therapy
BD Lehmann, JA Pietenpol, AR Tan
American Society of Clinical Oncology Educational Book 35 (1), e31-e39, 2015
1682015
Clinical implications of molecular heterogeneity in triple negative breast cancer
BD Lehmann, JA Pietenpol
The Breast 24, S36-S40, 2015
1342015
Mislocalization of the cell polarity protein scribble promotes mammary tumorigenesis and is associated with basal breast cancer
ME Feigin, SD Akshinthala, K Araki, AZ Rosenberg, LB Muthuswamy, ...
Cancer research 74 (11), 3180-3194, 2014
1332014
Targeting prostate cancer based on signal transduction and cell cycle pathways
JT Lee, BD Lehmann, DM Terrian, WH Chappell, F Stivala, M Libra, ...
Cell cycle 7 (12), 1745-1762, 2008
1332008
p53 expression controls prostate cancer sensitivity to chemotherapy and the MDM2 inhibitor Nutlin-3
WH Chappell, BD Lehmann, DM Terrian, SL Abrams, LS Steelman, ...
Cell cycle 11 (24), 4579-4588, 2012
1312012
A randomized phase II neoadjuvant study of cisplatin, paclitaxel with or without everolimus in patients with stage II/III triple-negative breast cancer (TNBC): responses and …
B Jovanović, IA Mayer, EL Mayer, VG Abramson, A Bardia, ME Sanders, ...
Clinical Cancer Research 23 (15), 4035-4045, 2017
1282017
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