Applications of 19F-NMR in Fragment-Based Drug Discovery RS Norton, EWW Leung, IR Chandrashekaran, CA MacRaild Molecules 21 (7), 860, 2016 | 101 | 2016 |
Promiscuous 2-aminothiazoles (PrATs): a frequent hitting scaffold SM Devine, MD Mulcair, CO Debono, EWW Leung, JWM Nissink, SS Lim, ... Journal of medicinal chemistry 58 (3), 1205-1214, 2015 | 92 | 2015 |
EGCG disaggregates amyloid-like fibrils formed by Plasmodium falciparum merozoite surface protein 2 IR Chandrashekaran, CG Adda, CA MacRaild, RF Anders, RS Norton Archives of biochemistry and biophysics 513 (2), 153-157, 2011 | 51 | 2011 |
Suppressor of Cytokine Signaling (SOCS) 5 utilises distinct domains for regulation of JAK1 and interaction with the adaptor protein Shc-1 EM Linossi, IR Chandrashekaran, TB Kolesnik, JM Murphy, AI Webb, ... PloS one 8 (8), e70536, 2013 | 50 | 2013 |
The N‐terminal domains of SOCS proteins: A conserved region in the disordered N‐termini of SOCS4 and 5 ZP Feng, IR Chandrashekaran, A Low, TP Speed, SE Nicholson, ... Proteins: Structure, Function, and Bioinformatics 80 (3), 946-957, 2012 | 50 | 2012 |
Merozoite surface protein 2 of Plasmodium falciparum: Expression, structure, dynamics, and fibril formation of the conserved N‐terminal domain A Low, IR Chandrashekaran, CG Adda, S Yao, JK Sabo, X Zhang, ... Biopolymers: Original Research on Biomolecules 87 (1), 12-22, 2007 | 50 | 2007 |
Inhibition by Flavonoids of Amyloid-like Fibril Formation by Plasmodium falciparum Merozoite Surface Protein 2 IR Chandrashekaran, CG Adda, CA MacRaild, RF Anders, RS Norton Biochemistry 49 (28), 5899-5908, 2010 | 42 | 2010 |
Three-dimensional structure of the mammalian tachykinin peptide neurokinin A bound to lipid micelles IR Chandrashekar, SM Cowsik Biophysical journal 85 (6), 4002-4011, 2003 | 40 | 2003 |
A natural product compound inhibits coronaviral replication in vitro by binding to the conserved Nsp9 SARS-CoV-2 protein DR Littler, M Liu, JL McAuley, SA Lowery, PT Illing, BS Gully, AW Purcell, ... Journal of Biological Chemistry 297 (6), 2021 | 37 | 2021 |
The N-terminal subdomain of insulin-like growth factor (IGF) binding protein 6. Structure and interaction with IGFs IR Chandrashekaran, S Yao, CC Wang, PS Bansal, PF Alewood, ... Biochemistry 46 (11), 3065-3074, 2007 | 33 | 2007 |
Structure and Dynamics of Apical Membrane Antigen 1 from Plasmodium falciparum FVO SS Lim, W Yang, B Krishnarjuna, K Kannan Sivaraman, ... Biochemistry 53 (46), 7310-7320, 2014 | 32 | 2014 |
Development of inhibitors of Plasmodium falciparum apical membrane antigen 1 based on fragment screening CO Debono, CA MacRaild, IR Chandrashekaran, O Dolezal, RF Anders, ... Australian Journal of Chemistry 66 (12), 1530-1536, 2013 | 32 | 2013 |
Three dimensional structure of mammalian tachykinin peptide neurokinin B bound to lipid micelles AK Mantha, IR Chandrashekar, NZ Baquer, SM Cowsik Journal of Biomolecular Structure and Dynamics 22 (2), 137-147, 2004 | 31 | 2004 |
Solution structure of the tachykinin peptide eledoisin RCR Grace, IR Chandrashekar, SM Cowsik Biophysical journal 84 (1), 655-664, 2003 | 31 | 2003 |
Membrane-induced structure of the mammalian tachykinin Neuropeptide gamma IR Chandrashekar, A Dike, SM Cowsik Journal of structural biology 148 (3), 315-325, 2004 | 23 | 2004 |
A ligand-induced structural change in fatty acid–binding protein 1 is associated with potentiation of peroxisome proliferator–activated receptor α agonists R Patil, B Mohanty, B Liu, IR Chandrashekaran, SJ Headey, ML Williams, ... Journal of Biological Chemistry 294 (10), 3720-3734, 2019 | 19 | 2019 |
Structure and functional characterization of the conserved JAK interaction region in the intrinsically disordered N-terminus of SOCS5 IR Chandrashekaran, B Mohanty, EM Linossi, LF Dagley, EWW Leung, ... Biochemistry 54 (30), 4672-4682, 2015 | 15 | 2015 |
Molecular modeling of the peptide agonist-binding site in a neurokinin-2 receptor IR Chandrashekaran, GS Rao, SM Cowsik Journal of chemical information and modeling 49 (7), 1734-1740, 2009 | 13 | 2009 |
Solution NMR characterization of apical membrane antigen 1 and small molecule interactions as a basis for designing new antimalarials B Krishnarjuna, SS Lim, SM Devine, CO Debono, R Lam, ... Journal of Molecular Recognition 29 (6), 281-291, 2016 | 11 | 2016 |
A critical evaluation of pyrrolo [2, 3-d] pyrimidine-4-amines as Plasmodium falciparum apical membrane antigen 1 (AMA1) inhibitors S SuiáLim MedChemComm 5 (10), 1500-1506, 2014 | 9 | 2014 |