Следене
Diana van Heemst
Diana van Heemst
Associate professor, Leiden University Medical Center
Потвърден имейл адрес: lumc.nl
Заглавие
Позовавания
Позовавания
Година
Defining the role of common variation in the genomic and biological architecture of adult human height
AR Wood, T Esko, J Yang, S Vedantam, TH Pers, S Gustafsson, AY Chu, ...
Nature genetics 46 (11), 1173-1186, 2014
21662014
Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals
Z Dastani, MF Hivert, N Timpson, JRB Perry, X Yuan, RA Scott, ...
PLoS genetics 8 (3), e1002607, 2012
5832012
Ageing, age-related diseases and oxidative stress: What to do next?
J Luo, K Mills, S le Cessie, R Noordam, D van Heemst
Ageing research reviews 57, 100982, 2020
5332020
The trans-ancestral genomic architecture of glycemic traits
J Chen, CN Spracklen, G Marenne, A Varshney, LJ Corbin, J Luan, ...
Nature genetics 53 (6), 840-860, 2021
5232021
Disease variants alter transcription factor levels and methylation of their binding sites
MJ Bonder, R Luijk, DV Zhernakova, M Moed, P Deelen, M Vermaat, ...
Nature genetics 49 (1), 131-138, 2017
4942017
Identification of context-dependent expression quantitative trait loci in whole blood
DV Zhernakova, P Deelen, M Vermaat, M Van Iterson, M Van Galen, ...
Nature genetics 49 (1), 139-145, 2017
4762017
Genome-wide association study in 79,366 European-ancestry individuals informs the genetic architecture of 25-hydroxyvitamin D levels
X Jiang, PF O’Reilly, H Aschard, YH Hsu, JB Richards, J Dupuis, ...
Nature communications 9 (1), 260, 2018
4372018
Genome analyses of> 200,000 individuals identify 58 loci for chronic inflammation and highlight pathways that link inflammation and complex disorders
S Ligthart, A Vaez, U Võsa, MG Stathopoulou, PS De Vries, BP Prins, ...
The American Journal of Human Genetics 103 (5), 691-706, 2018
4042018
Telomere length in white blood cells is not associated with morbidity or mortality in the oldest old: a population‐based study
CM Martin‐Ruiz, J Gussekloo, D Van Heemst, T Von Zglinicki, ...
Aging cell 4 (6), 287-290, 2005
3932005
Genetic and environmental influences interact with age and sex in shaping the human methylome
J Van Dongen, MG Nivard, G Willemsen, JJ Hottenga, Q Helmer, ...
Nature communications 7 (1), 11115, 2016
3912016
Nbs1 is essential for DNA repair by homologous recombination in higher vertebrate cells
H Tauchi, J Kobayashi, K Morishima, DC Van Gent, T Shiraishi, ...
Nature 420 (6911), 93-98, 2002
3762002
Reduced insulin/IGF‐1 signalling and human longevity
D Van Heemst, M Beekman, SP Mooijaart, BT Heijmans, BW Brandt, ...
Aging cell 4 (2), 79-85, 2005
3682005
Insulin, IGF-1 and longevity
D Van Heemst
Aging and disease 1 (2), 147, 2010
3522010
Genome‐wide association study identifies a single major locus contributing to survival into old age; the APOE locus revisited
J Deelen, M Beekman, HW Uh, Q Helmer, M Kuningas, L Christiansen, ...
Aging cell 10 (4), 686-698, 2011
3302011
Nonagenarian siblings and their offspring display lower risk of mortality and morbidity than sporadic nonagenarians: The Leiden Longevity Study
RGJ Westendorp, D Van Heemst, MP Rozing, M Frölich, SP Mooijaart, ...
Journal of the American Geriatrics Society 57 (9), 1634-1637, 2009
3182009
A meta-analysis of genome-wide association studies identifies multiple longevity genes
J Deelen, DS Evans, DE Arking, N Tesi, M Nygaard, X Liu, MK Wojczynski, ...
Nature communications 10 (1), 3669, 2019
3102019
Genomic and phenotypic insights from an atlas of genetic effects on DNA methylation
JL Min, G Hemani, E Hannon, KF Dekkers, J Castillo-Fernandez, R Luijk, ...
Nature genetics 53 (9), 1311-1321, 2021
3072021
Genome-wide association meta-analysis of human longevity identifies a novel locus conferring survival beyond 90 years of age
J Deelen, M Beekman, HW Uh, L Broer, KL Ayers, Q Tan, Y Kamatani, ...
Human molecular genetics 23 (16), 4420-4432, 2014
3032014
A metabolic profile of all-cause mortality risk identified in an observational study of 44,168 individuals
J Deelen, J Kettunen, K Fischer, A van Der Spek, S Trompet, ...
Nature communications 10 (1), 3346, 2019
3002019
The number of p16INK4a positive cells in human skin reflects biological age
MEC Waaijer, WE Parish, BH Strongitharm, D van Heemst, PE Slagboom, ...
Aging cell 11 (4), 722-725, 2012
2932012
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