| Perforin and granzymes: function, dysfunction and human pathology I Voskoboinik, JC Whisstock, JA Trapani Nature Reviews Immunology 15 (6), 388-400, 2015 | 1215 | 2015 |
| CMTM6 maintains the expression of PD-L1 and regulates anti-tumour immunity ML Burr, CE Sparbier, YC Chan, JC Williamson, K Woods, PA Beavis, ... Nature 549 (7670), 101-105, 2017 | 738 | 2017 |
| Perforin-mediated target-cell death and immune homeostasis I Voskoboinik, MJ Smyth, JA Trapani Nature Reviews Immunology 6 (12), 940-952, 2006 | 716 | 2006 |
| The structural basis for membrane binding and pore formation by lymphocyte perforin RHP Law, N Lukoyanova, I Voskoboinik, TT Caradoc-Davies, K Baran, ... Nature 468 (7322), 447-451, 2010 | 473 | 2010 |
| The MACPF/CDC family of pore‐forming toxins CJ Rosado, S Kondos, TE Bull, MJ Kuiper, RHP Law, AM Buckle, ... Cellular microbiology 10 (9), 1765-1774, 2008 | 339 | 2008 |
| A common fold mediates vertebrate defense and bacterial attack CJ Rosado, AM Buckle, RHP Law, RE Butcher, WT Kan, CH Bird, K Ung, ... Science 317 (5844), 1548-1551, 2007 | 324 | 2007 |
| Perforin forms transient pores on the target cell plasma membrane to facilitate rapid access of granzymes during killer cell attack JA Lopez, O Susanto, MR Jenkins, N Lukoyanova, VR Sutton, RHP Law, ... Blood, The Journal of the American Society of Hematology 121 (14), 2659-2668, 2013 | 315 | 2013 |
| Molecular mechanisms of copper homeostasis J Camakaris, I Voskoboinik, JF Mercer Biochemical and biophysical research communications 261 (2), 225-232, 1999 | 310 | 1999 |
| Perforin: structure, function, and role in human immunopathology I Voskoboinik, MA Dunstone, K Baran, JC Whisstock, JA Trapani Immunological reviews 235 (1), 35-54, 2010 | 292 | 2010 |
| Tumor immune evasion arises through loss of TNF sensitivity CJ Kearney, SJ Vervoort, SJ Hogg, KM Ramsbottom, AJ Freeman, ... Science immunology 3 (23), eaar3451, 2018 | 287 | 2018 |
| Failed CTL/NK cell killing and cytokine hypersecretion are directly linked through prolonged synapse time MR Jenkins, JA Rudd-Schmidt, JA Lopez, KM Ramsbottom, SI Mannering, ... Journal of Experimental Medicine 212 (3), 307-317, 2015 | 239 | 2015 |
| Calcium-dependent plasma membrane binding and cell lysis by perforin are mediated through its C2 domain: A critical role for aspartate residues 429, 435, 483, and 485 but not 491 I Voskoboinik, MC Thia, J Fletcher, A Ciccone, K Browne, MJ Smyth, ... Journal of Biological Chemistry 280 (9), 8426-8434, 2005 | 207 | 2005 |
| Apoptosis induced by the lymphocyte effector molecule perforin P Bolitho, I Voskoboinik, JA Trapani, MJ Smyth Current opinion in immunology 19 (3), 339-347, 2007 | 199 | 2007 |
| The molecular basis for perforin oligomerization and transmembrane pore assembly K Baran, M Dunstone, J Chia, A Ciccone, KA Browne, CJP Clarke, ... Immunity 30 (5), 684-695, 2009 | 172 | 2009 |
| Temperature sensitivity of human perforin mutants unmasks subtotal loss of cytotoxicity, delayed FHL, and a predisposition to cancer J Chia, KP Yeo, JC Whisstock, MA Dunstone, JA Trapani, I Voskoboinik Proceedings of the National Academy of Sciences 106 (24), 9809-9814, 2009 | 163 | 2009 |
| Functional analysis of the N-terminal CXXC metal-binding motifs in the human Menkes copper-transporting P-type ATPase expressed in cultured mammalian cells I Voskoboinik, D Strausak, M Greenough, H Brooks, M Petris, S Smith, ... Journal of Biological Chemistry 274 (31), 22008-22012, 1999 | 160 | 1999 |
| Copper-regulated trafficking of the Menkes disease copper ATPase is associated with formation of a phosphorylated catalytic intermediate MJ Petris, I Voskoboinik, M Cater, K Smith, BE Kim, RM Llanos, ... Journal of Biological Chemistry 277 (48), 46736-46742, 2002 | 155 | 2002 |
| Conformational changes during pore formation by the perforin-related protein pleurotolysin N Lukoyanova, SC Kondos, I Farabella, RHP Law, CF Reboul, ... PLoS biology 13 (2), e1002049, 2015 | 139 | 2015 |
| Signals regulating trafficking of Menkes (MNK; ATP7A) copper-translocating P-type ATPase in polarized MDCK cells M Greenough, L Pase, I Voskoboinik, MJ Petris, AW O'Brien, J Camakaris American Journal of Physiology-Cell Physiology 287 (5), C1463-C1471, 2004 | 139 | 2004 |
| The regulation of catalytic activity of the menkes copper-translocating P-type ATPase: role of high affinity copper-binding sites I Voskoboinik, J Mar, D Strausak, J Camakaris Journal of Biological Chemistry 276 (30), 28620-28627, 2001 | 134 | 2001 |
