DNA binding site sequence directs glucocorticoid receptor structure and activity SH Meijsing, MA Pufall, AY So, DL Bates, L Chen, KR Yamamoto Science 324 (5925), 407-410, 2009 | 796 | 2009 |
Reversible targeting of noncatalytic cysteines with chemically tuned electrophiles IM Serafimova, MA Pufall, S Krishnan, K Duda, MS Cohen, RL Maglathlin, ... Nature chemical biology 8 (5), 471-476, 2012 | 583 | 2012 |
Variable control of Ets-1 DNA binding by multiple phosphates in an unstructured region MA Pufall, GM Lee, ML Nelson, HS Kang, A Velyvis, LE Kay, LP McIntosh, ... science 309 (5731), 142-145, 2005 | 286 | 2005 |
Autoinhibitory domains: modular effectors of cellular regulation MA Pufall, BJ Graves Annual review of cell and developmental biology 18 (1), 421-462, 2002 | 272 | 2002 |
Glucocorticoids and cancer MA Pufall Glucocorticoid Signaling: From Molecules to Mice to Man, 315-333, 2015 | 230 | 2015 |
Metabolic gatekeeper function of B-lymphoid transcription factors LN Chan, Z Chen, D Braas, JW Lee, G Xiao, H Geng, KN Cosgun, C Hurtz, ... Nature 542 (7642), 479-483, 2017 | 229 | 2017 |
The glucocorticoid receptor dimer interface allosterically transmits sequence-specific DNA signals LC Watson, KM Kuchenbecker, BJ Schiller, JD Gross, MA Pufall, ... Nature structural & molecular biology 20 (7), 876-883, 2013 | 181 | 2013 |
Transcriptional Regulation of Human Dual Specificity Protein Phosphatase 1 (DUSP1) Gene by Glucocorticoids LE Shipp, JV Lee, CY Yu, M Pufall, P Zhang, DK Scott, JC Wang PLoS One 5 (10), e13754, 2010 | 123 | 2010 |
Structural analysis of the autoinhibition of Ets-1 and its role in protein partnerships CW Garvie, MA Pufall, BJ Graves, C Wolberger Journal of Biological Chemistry 277 (47), 45529-45536, 2002 | 123 | 2002 |
The structural and dynamic basis of Ets-1 DNA binding autoinhibition GM Lee, LW Donaldson, MA Pufall, HS Kang, I Pot, BJ Graves, ... Journal of Biological Chemistry 280 (8), 7088-7099, 2005 | 118 | 2005 |
JUNB is a key transcriptional modulator of macrophage activation MF Fontana, A Baccarella, N Pancholi, MA Pufall, DBR Herbert, CC Kim The Journal of Immunology 194 (1), 177-186, 2015 | 115 | 2015 |
EC coupling structural protein junctophilin-2 encodes a stress-adaptive transcription regulator A Guo, Y Wang, B Chen, Y Wang, J Yuan, L Zhang, D Hall, J Wu, Y Shi, ... Science 362 (6421), eaan3303, 2018 | 111 | 2018 |
DNA mismatches reveal conformational penalties in protein–DNA recognition A Afek, H Shi, A Rangadurai, H Sahay, A Senitzki, S Xhani, M Fang, ... Nature 587 (7833), 291-296, 2020 | 108 | 2020 |
The affinity of Ets-1 for DNA is modulated by phosphorylation through transient interactions of an unstructured region GM Lee, MA Pufall, CA Meeker, HS Kang, BJ Graves, LP McIntosh Journal of molecular biology 382 (4), 1014-1030, 2008 | 75 | 2008 |
A naturally occuring insertion of a single amino acid rewires transcriptional regulation by glucocorticoid receptor isoforms M Thomas-Chollier, LC Watson, SB Cooper, MA Pufall, JS Liu, K Borzym, ... Proceedings of the National Academy of Sciences 110 (44), 17826-17831, 2013 | 67 | 2013 |
Suppression of B-cell development genes is key to glucocorticoid efficacy in treatment of acute lymphoblastic leukemia KA Kruth, M Fang, DN Shelton, O Abu-Halawa, R Mahling, H Yang, ... Blood, The Journal of the American Society of Hematology 129 (22), 3000-3008, 2017 | 58 | 2017 |
Spermine oxidase maintains basal skeletal muscle gene expression and fiber size and is strongly repressed by conditions that cause skeletal muscle atrophy KS Bongers, DK Fox, SD Kunkel, LV Stebounova, DJ Murry, MA Pufall, ... American Journal of Physiology-Endocrinology and Metabolism 308 (2), E144-E158, 2015 | 56 | 2015 |
Response element composition governs correlations between binding site affinity and transcription in glucocorticoid receptor feed-forward loops SK Sasse, Z Zuo, V Kadiyala, L Zhang, MA Pufall, MK Jain, TL Phang, ... Journal of Biological Chemistry 290 (32), 19756-19769, 2015 | 45 | 2015 |
Nascent transcript analysis of glucocorticoid crosstalk with TNF defines primary and cooperative inflammatory repression SK Sasse, M Gruca, MA Allen, V Kadiyala, T Song, F Gally, A Gupta, ... Genome research 29 (11), 1753-1765, 2019 | 43 | 2019 |
Neuronal PAS domain proteins 1 and 3 are master regulators of neuropsychiatric risk genes JJ Michaelson, MK Shin, JY Koh, L Brueggeman, A Zhang, A Katzman, ... Biological psychiatry 82 (3), 213-223, 2017 | 40 | 2017 |