Jaime Grutzendler
Jaime Grutzendler
Professor of Neurology and Neuroscience, Yale University
Потвърден имейл адрес: yale.edu - Начална страница
ATP mediates rapid microglial response to local brain injury in vivo
D Davalos, J Grutzendler, G Yang, JV Kim, Y Zuo, S Jung, DR Littman, ...
Nature neuroscience 8 (6), 752-758, 2005
Long-term dendritic spine stability in the adult cortex
J Grutzendler, N Kasthuri, WB Gan
Nature 420 (6917), 812-816, 2002
Two modes of radial migration in early development of the cerebral cortex
B Nadarajah, JE Brunstrom, J Grutzendler, ROL Wong, AL Pearlman
Nature neuroscience 4 (2), 143-150, 2001
TREM2 haplodeficiency in mice and humans impairs the microglia barrier function leading to decreased amyloid compaction and severe axonal dystrophy
P Yuan, C Condello, CD Keene, Y Wang, TD Bird, SM Paul, W Luo, ...
Neuron 90 (4), 724-739, 2016
TREM2-mediated early microglial response limits diffusion and toxicity of amyloid plaques
Y Wang, TK Ulland, JD Ulrich, W Song, JA Tzaferis, JT Hole, P Yuan, ...
Journal of Experimental Medicine 213 (5), 667-675, 2016
Regional blood flow in the normal and ischemic brain is controlled by arteriolar smooth muscle cell contractility and not by capillary pericytes
RA Hill, L Tong, P Yuan, S Murikinati, S Gupta, J Grutzendler
Neuron 87 (1), 95-110, 2015
Fibrillar amyloid deposition leads to local synaptic abnormalities and breakage of neuronal branches
J Tsai, J Grutzendler, K Duff, WB Gan
Nature neuroscience 7 (11), 1181-1183, 2004
Microglia constitute a barrier that prevents neurotoxic protofibrillar Aβ42 hotspots around plaques
C Condello, P Yuan, A Schain, J Grutzendler
Nature communications 6 (1), 6176, 2015
Thinned-skull cranial window technique for long-term imaging of the cortex in live mice
G Yang, F Pan, CN Parkhurst, J Grutzendler, WB Gan
Nature protocols 5 (2), 201-208, 2010
Multicolor “DiOlistic” labeling of the nervous system using lipophilic dye combinations
WB Gan, J Grutzendler, WT Wong, ROL Wong, JW Lichtman
Neuron 27 (2), 219-225, 2000
Lifelong cortical myelin plasticity and age-related degeneration in the live mammalian brain
RA Hill, AM Li, J Grutzendler
Nature neuroscience 21 (5), 683-695, 2018
Cholinesterase inhibitors for Alzheimer’s disease
J Grutzendler, JC Morris
Drugs 61, 41-52, 2001
Massive accumulation of luminal protease-deficient axonal lysosomes at Alzheimer’s disease amyloid plaques
S Gowrishankar, P Yuan, Y Wu, M Schrag, S Paradise, J Grutzendler, ...
Proceedings of the National Academy of Sciences 112 (28), E3699-E3708, 2015
CX3CR1 in microglia regulates brain amyloid deposition through selective protofibrillar amyloid-β phagocytosis
Z Liu, C Condello, A Schain, R Harb, J Grutzendler
Journal of Neuroscience 30 (50), 17091-17101, 2010
Embolus extravasation is an alternative mechanism for cerebral microvascular recanalization
CK Lam, T Yoo, B Hiner, Z Liu, J Grutzendler
Nature 465 (7297), 478-482, 2010
Various dendritic abnormalities are associated with fibrillar amyloid deposits in Alzheimer's disease
J Grutzendler, K Helmin, J Tsai, WENB GAN
Annals of the New York Academy of Sciences 1097 (1), 30-39, 2007
Astrocytes and microglia play orchestrated roles and respect phagocytic territories during neuronal corpse removal in vivo
EC Damisah, RA Hill, A Rai, F Chen, CV Rothlin, S Ghosh, J Grutzendler
Science Advances 6 (26), eaba3239, 2020
In Vivo Imaging of Cerebral Microvascular Plasticity from Birth to Death
R Harb, C Whiteus, C Freitas, J Grutzendler
Journal of Cerebral Blood Flow & Metabolism 33 (1), 146-156, 2013
Label-free in vivo imaging of myelinated axons in health and disease with spectral confocal reflectance microscopy
AJ Schain, RA Hill, J Grutzendler
Nature medicine 20 (4), 443-449, 2014
Modulation of oligodendrocyte generation during a critical temporal window after NG2 cell division
RA Hill, KD Patel, CM Goncalves, J Grutzendler, A Nishiyama
Nature neuroscience 17 (11), 1518-1527, 2014
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