Cysteine depletion induces pancreatic tumor ferroptosis in mice MA Badgley, DM Kremer, HC Maurer, KE DelGiorno, HJ Lee, V Purohit, ... Science 368 (6486), 85-89, 2020 | 914 | 2020 |
MUC1 and HIF-1alpha signaling crosstalk induces anabolic glucose metabolism to impart gemcitabine resistance to pancreatic cancer SK Shukla, V Purohit, K Mehla, V Gunda, NV Chaika, E Vernucci, RJ King, ... Cancer cell 32 (1), 71-87. e7, 2017 | 496 | 2017 |
Metabolic reprogramming induced by ketone bodies diminishes pancreatic cancer cachexia SK Shukla, T Gebregiworgis, V Purohit, NV Chaika, V Gunda, ... Cancer & metabolism 2, 1-19, 2014 | 260 | 2014 |
Graviola: a novel promising natural-derived drug that inhibits tumorigenicity and metastasis of pancreatic cancer cells in vitro and in vivo through altering cell metabolism MP Torres, S Rachagani, V Purohit, P Pandey, S Joshi, ED Moore, ... Cancer letters 323 (1), 29-40, 2012 | 259 | 2012 |
MUC1 mucin stabilizes and activates hypoxia-inducible factor 1 alpha to regulate metabolism in pancreatic cancer NV Chaika, T Gebregiworgis, ME Lewallen, V Purohit, P Radhakrishnan, ... Proceedings of the National Academy of Sciences 109 (34), 13787-13792, 2012 | 234 | 2012 |
Differential expression of metabolic genes in tumor and stromal components of primary and metastatic loci in pancreatic adenocarcinoma NV Chaika, F Yu, V Purohit, K Mehla, AJ Lazenby, D DiMaio, ... PloS one 7 (3), e32996, 2012 | 111 | 2012 |
Active YAP promotes pancreatic cancer cell motility, invasion and tumorigenesis in a mitotic phosphorylation-dependent manner through LPAR3 S Yang, L Zhang, V Purohit, SK Shukla, X Chen, F Yu, K Fu, Y Chen, ... Oncotarget 6 (34), 36019, 2015 | 106 | 2015 |
Metabolic regulation of redox balance in cancer V Purohit, DM Simeone, CA Lyssiotis Cancers 11 (7), 955, 2019 | 105 | 2019 |
High-content fluorescence imaging with the metabolic flux assay reveals insights into mitochondrial properties and functions AC Little, I Kovalenko, LE Goo, HS Hong, SA Kerk, JA Yates, V Purohit, ... Communications biology 3 (1), 271, 2020 | 69 | 2020 |
MUC1 facilitates metabolomic reprogramming in triple-negative breast cancer G Goode, V Gunda, NV Chaika, V Purohit, F Yu, PK Singh PloS one 12 (5), e0176820, 2017 | 48 | 2017 |
Systems-based approaches to study immunometabolism V Purohit, A Wagner, N Yosef, VK Kuchroo Cellular & molecular immunology 19 (3), 409-420, 2022 | 37 | 2022 |
Tim-3 adapter protein Bat3 acts as an endogenous regulator of tolerogenic dendritic cell function R Tang, N Acharya, A Subramanian, V Purohit, M Tabaka, Y Hou, D He, ... Science immunology 7 (69), eabm0631, 2022 | 32 | 2022 |
ATDC binds to KEAP1 to drive NRF2-mediated tumorigenesis and chemoresistance in pancreatic cancer V Purohit, L Wang, H Yang, J Li, GM Ney, ER Gumkowski, AJ Vaidya, ... Genes & Development, 2021 | 30 | 2021 |
Insights into gemcitabine resistance and the potential for therapeutic monitoring T Gebregiworgis, F Bhinderwala, V Purohit, NV Chaika, PK Singh, ... Metabolomics 14, 1-7, 2018 | 30 | 2018 |
Glucose limitation alters glutamine metabolism in MUC1-overexpressing pancreatic cancer cells T Gebregiworgis, V Purohit, SK Shukla, S Tadros, NV Chaika, J Abrego, ... Journal of proteome research 16 (10), 3536-3546, 2017 | 30 | 2017 |
ATDC is required for the initiation of KRAS-induced pancreatic tumorigenesis L Wang, H Yang, A Zamperone, D Diolaiti, PL Palmbos, EV Abel, ... Genes & Development 33 (11-12), 641-655, 2019 | 23 | 2019 |
Correction: MUC1 facilitates metabolomic reprogramming in triple-negative breast cancer G Goode, V Gunda, NV Chaika, V Purohit, F Yu, PK Singh Plos one 12 (6), e0179098, 2017 | 4 | 2017 |
Graviola:-Novel promising natural derived drug that inhibits tumorigenicity and metastasis of pancreatic cancer cell in vitro and in vivo through alternating cell metabolism … MP Torves, S Rachagani, V Purohit, P Pandey, S Joshi, ED Moore, ... Cancer cell, Letters 323, 29-40, 2012 | 3 | 2012 |
Induction of pancreatic tumor-selective ferroptosis through modulation of cystine import MA Badgley, D Kremer, HC Maurer, KE DelGiorno, HJ Lee, V Purohit, ... BioRxiv, 827972, 2019 | 2 | 2019 |
Möglichkeiten und Grenzen der ketogenen Ernährung in der Krebstherapie U Kämmerer, RJ Klement Zeitschrift für Orthomolekulare Medizin 15 (02), 20-24, 2017 | 2 | 2017 |