Isaac Kohane
Isaac Kohane
Harvard Medical School, Children's Hospital, Brigham and Women's Hospital
Verified email at hms.harvard.edu - Homepage
TitleCited byYear
Comprehensive genomic characterization defines human glioblastoma genes and core pathways
Cancer Genome Atlas Research Network
Nature 455 (7216), 1061, 2008
48612008
Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: Potential role of PGC1 and NRF1
ME Patti, AJ Butte, S Crunkhorn, K Cusi, R Berria, S Kashyap, Y Miyazaki, ...
Proceedings of the National Academy of Sciences 100 (14), 8466-8471, 2003
19612003
Gene regulation and DNA damage in the ageing human brain
T Lu, Y Pan, SY Kao, C Li, I Kohane, J Chan, BA Yankner
Nature 429 (6994), 883, 2004
16282004
Mutual information relevance networks: functional genomic clustering using pairwise entropy measurements
AJ Butte, IS Kohane
Biocomputing 2000, 418-429, 1999
11341999
A mega-analysis of genome-wide association studies for major depressive disorder
S Ripke, NR Wray, CM Lewis, SP Hamilton, MM Weissman, G Breen, ...
Molecular psychiatry 18 (4), 497, 2013
8722013
A signature of chromosomal instability inferred from gene expression profiles predicts clinical outcome in multiple human cancers
SL Carter, AC Eklund, IS Kohane, LN Harris, Z Szallasi
Nature genetics 38 (9), 1043, 2006
8562006
Discovering statistically significant pathways in expression profiling studies
L Tian, SA Greenberg, SW Kong, J Altschuler, IS Kohane, PJ Park
Proceedings of the National Academy of Sciences 102 (38), 13544-13549, 2005
7102005
Discovering functional relationships between RNA expression and chemotherapeutic susceptibility using relevance networks
AJ Butte, P Tamayo, D Slonim, TR Golub, IS Kohane
Proceedings of the National Academy of Sciences 97 (22), 12182-12186, 2000
6792000
Serving the enterprise and beyond with informatics for integrating biology and the bedside (i2b2)
SN Murphy, G Weber, M Mendis, V Gainer, HC Chueh, S Churchill, ...
Journal of the American Medical Informatics Association 17 (2), 124-130, 2010
6312010
Analysis of matched mRNA measurements from two different microarray technologies
WP Kuo, TK Jenssen, AJ Butte, L Ohno-Machado, IS Kohane
Bioinformatics 18 (3), 405-412, 2002
5782002
Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression
NR Wray, S Ripke, M Mattheisen, M Trzaskowski, EM Byrne, A Abdellaoui, ...
Nature genetics 50 (5), 668, 2018
5652018
Human disease classification in the postgenomic era: a complex systems approach to human pathobiology
J Loscalzo, I Kohane, AL Barabasi
Molecular systems biology 3 (1), 2007
5432007
Cluster analysis of gene expression dynamics
MF Ramoni, P Sebastiani, IS Kohane
Proceedings of the National Academy of Sciences 99 (14), 9121-9126, 2002
5072002
Distinctive patterns of microRNA expression in primary muscular disorders
I Eisenberg, A Eran, I Nishino, M Moggio, C Lamperti, AA Amato, ...
Proceedings of the National Academy of Sciences 104 (43), 17016-17021, 2007
4592007
Public standards and patients' control: how to keep electronic medical records accessible but privateMedical information: access and privacyDoctrines for developing electronic …
KD Mandl, D Markwell, R MacDonald, P Szolovits, IS Kohane
Bmj 322 (7281), 283-287, 2001
4282001
Managing incidental findings and research results in genomic research involving biobanks and archived data sets
SM Wolf, BN Crock, B Van Ness, F Lawrenz, JP Kahn, LM Beskow, ...
Genetics in Medicine 14 (4), 361, 2012
4002012
The co-morbidity burden of children and young adults with autism spectrum disorders
IS Kohane, A McMurry, G Weber, D MacFadden, L Rappaport, L Kunkel, ...
PloS one 7 (4), e33224, 2012
3602012
Electronic patient-physician communication: problems and promise
KD Mandl, IS Kohane, AM Brandt
American College of Physicians, 1998
3481998
The electronic medical records and genomics (eMERGE) network: past, present, and future
O Gottesman, H Kuivaniemi, G Tromp, WA Faucett, R Li, TA Manolio, ...
Genetics in Medicine 15 (10), 761, 2013
3462013
Quantifying the relationship between co-expression, co-regulation and gene function
DJ Allocco, IS Kohane, AJ Butte
BMC bioinformatics 5 (1), 18, 2004
3362004
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Articles 1–20