Direct observation of the nanoscale dynamics of membrane lipids in a living cell C Eggeling, C Ringemann, R Medda, G Schwarzmann, K Sandhoff, ... Nature 457 (7233), 1159-1162, 2009 | 1745 | 2009 |
CD95 signaling via ceramide-rich membrane rafts H Grassmé, A Jekle, A Riehle, H Schwarz, J Berger, K Sandhoff, ... Journal of Biological Chemistry 276 (23), 20589-20596, 2001 | 799 | 2001 |
Enhanced insulin sensitivity in mice lacking ganglioside GM3 T Yamashita, A Hashiramoto, M Haluzik, H Mizukami, S Beck, A Norton, ... Proceedings of the National Academy of Sciences 100 (6), 3445-3449, 2003 | 618 | 2003 |
A vital role for glycosphingolipid synthesis during development and differentiation T Yamashita, R Wada, T Sasaki, C Deng, U Bierfreund, K Sandhoff, ... Proceedings of the National Academy of Sciences 96 (16), 9142-9147, 1999 | 604 | 1999 |
Principles of lysosomal membrane digestion: stimulation of sphingolipid degradation by sphingolipid activator proteins and anionic lysosomal lipids T Kolter, K Sandhoff Annu. Rev. Cell Dev. Biol. 21, 81-103, 2005 | 569 | 2005 |
Acid sphingomyelinase deficient mice: a model of types A and B Niemann–Pick disease K Horinouchi, S Erlich, DP Perl, K Ferlinz, CL Bisgaier, K Sandhoff, ... Nature genetics 10 (3), 288-293, 1995 | 569 | 1995 |
Physiology and pathophysiology of sphingolipid metabolism and signaling A Huwiler, T Kolter, J Pfeilschifter, K Sandhoff BBA-Molecular and Cell Biology of Lipids 2 (1485), 63-99, 2000 | 561 | 2000 |
Hsp70 stabilizes lysosomes and reverts Niemann–Pick disease-associated lysosomal pathology T Kirkegaard, AG Roth, NHT Petersen, AK Mahalka, OD Olsen, I Moilanen, ... Nature 463 (7280), 549-553, 2010 | 560 | 2010 |
Apoptotic vesicles crossprime CD8 T cells and protect against tuberculosis F Winau, S Weber, S Sad, J De Diego, SL Hoops, B Breiden, K Sandhoff, ... Immunity 24 (1), 105-117, 2006 | 514 | 2006 |
Sphingolipids—their metabolic pathways and the pathobiochemistry of neurodegenerative diseases T Kolter, K Sandhoff Angewandte Chemie International Edition 38 (11), 1532-1568, 1999 | 504 | 1999 |
Mouse models of Tay–Sachs and Sandhoff diseases differ in neurologic phenotype and ganglioside metabolism K Sango, S Yamanaka, A Hoffmann, Y Okuda, A Grinberg, H Westphal, ... Nature genetics 11 (2), 170-176, 1995 | 497 | 1995 |
Deficient hexosaminidase activity in an exceptional case of Tay-Sachs disease with additional storage of kidney globoside in visceral organs K Sandhoff, U Andreae, H Jatzkewitz Life sciences 7 (6), 283-288, 1968 | 457 | 1968 |
Sphingolipid metabolism diseases T Kolter, K Sandhoff Biochimica et Biophysica Acta (BBA)-Biomembranes 1758 (12), 2057-2079, 2006 | 454 | 2006 |
Subcellular localization and membrane topology of serine palmitoyltransferase, 3-dehydrosphinganine reductase, and sphinganine N-acyltransferase in mouse liver. EC Mandon, I Ehses, J Rother, G van Echten, K Sandhoff Journal of Biological Chemistry 267 (16), 11144-11148, 1992 | 446 | 1992 |
Fumonisin B1 inhibits sphingosine (sphinganine) N-acyltransferase and de novo sphingolipid biosynthesis in cultured neurons in situ. AH Merrill Jr, G Van Echten, E Wang, K Sandhoff Journal of Biological Chemistry 268 (36), 27299-27306, 1993 | 440 | 1993 |
Combinatorial ganglioside biosynthesis T Kolter, RL Proia, K Sandhoff Journal of Biological Chemistry 277 (29), 25859-25862, 2002 | 420 | 2002 |
Acidic sphingomyelinase mediates entry of N. gonorrhoeae into nonphagocytic cells H Grassmé, E Gulbins, B Brenner, K Ferlinz, K Sandhoff, K Harzer, F Lang, ... Cell 91 (5), 605-615, 1997 | 410 | 1997 |
Ganglioside metabolism. Enzymology, topology, and regulation G Van Echten, K Sandhoff The Journal of biological chemistry 268 (8), 5341-5344, 1993 | 405 | 1993 |
Characterization of ceramide synthesis: a dihydroceramide desaturase introduces the 4, 5-trans-double bond of sphingosine at the level of dihydroceramide C Michel, G van Echten-Deckert, J Rother, K Sandhoff, E Wang, AH Merrill Journal of Biological Chemistry 272 (36), 22432-22437, 1997 | 384 | 1997 |
Activator proteins and topology of lysosomal sphingolipid catabolism W Fürst, K Sandhoff Biochimica et Biophysica Acta (BBA)-Lipids and Lipid Metabolism 1126 (1), 1-16, 1992 | 358 | 1992 |