The metabolite α-ketoglutarate extends lifespan by inhibiting ATP synthase and TOR RM Chin, X Fu, MY Pai, L Vergnes, H Hwang, G Deng, S Diep, ... Nature 510 (7505), 397-401, 2014 | 571 | 2014 |
O-GlcNAc: a regulatory post-translational modification L Wells, SA Whelan, GW Hart Biochemical and biophysical research communications 302 (3), 435-441, 2003 | 250 | 2003 |
Regulation of the O-linked β-N-acetylglucosamine transferase by insulin signaling SA Whelan, MD Lane, GW Hart Journal of Biological Chemistry 283 (31), 21411-21417, 2008 | 208 | 2008 |
Regulation of insulin receptor substrate 1 (IRS-1)/AKT kinase-mediated insulin signaling by O-linked β-N-acetylglucosamine in 3T3-L1 adipocytes SA Whelan, WB Dias, L Thiruneelakantapillai, MD Lane, GW Hart Journal of biological chemistry 285 (8), 5204-5211, 2010 | 190 | 2010 |
Proteomic approaches to analyze the dynamic relationships between nucleocytoplasmic protein glycosylation and phosphorylation SA Whelan, GW Hart Circulation research 93 (11), 1047-1058, 2003 | 175 | 2003 |
Biosynthetic machinery involved in aberrant glycosylation: promising targets for developing of drugs against cancer A Vasconcelos-dos-Santos, IA Oliveira, MC Lucena, NR Mantuano, ... Frontiers in oncology 5, 138, 2015 | 146 | 2015 |
Epithelial mesenchymal transition induces aberrant glycosylation through hexosamine biosynthetic pathway activation MC Lucena, P Carvalho-Cruz, JL Donadio, IA Oliveira, RM de Queiroz, ... Journal of Biological Chemistry 291 (25), 12917-12929, 2016 | 105 | 2016 |
Mass spectrometry (LC-MS/MS) site-mapping of N-glycosylated membrane proteins for breast cancer biomarkers SA Whelan, M Lu, J He, W Yan, RE Saxton, KF Faull, JP Whitelegge, ... Journal of proteome research 8 (8), 4151-4160, 2009 | 100 | 2009 |
Comparative proteomics reveals dysregulated mitochondrial O-GlcNAcylation in diabetic hearts J Ma, P Banerjee, SA Whelan, T Liu, AC Wei, G Ramirez-Correa, ... Journal of proteome research 15 (7), 2254-2264, 2016 | 69 | 2016 |
Mass spectrometry (LC–MS/MS) identified proteomic biosignatures of breast cancer in proximal fluid SA Whelan, J He, M Lu, P Souda, RE Saxton, KF Faull, JP Whitelegge, ... Journal of proteome research 11 (10), 5034-5045, 2012 | 62 | 2012 |
Identification of O‐GlcNAc sites on proteins SA Whelan, GW Hart Methods in enzymology 415, 113-133, 2006 | 52 | 2006 |
Proteomic-based biosignatures in breast cancer classification and prediction of therapeutic response J He, SA Whelan, M Lu, D Shen, DU Chung, RE Saxton, KF Faull, ... International journal of proteomics 2011, 2011 | 47 | 2011 |
Characterization of the human NEK7 interactome suggests catalytic and regulatory properties distinct from those of NEK6 EE de Souza, GV Meirelles, BB Godoy, AM Perez, JHC Smetana, ... Journal of proteome research 13 (9), 4074-4090, 2014 | 44 | 2014 |
Does reversible cysteine oxidation link the Western diet to cardiac dysfunction? JB Behring, V Kumar, SA Whelan, P Chauhan, DA Siwik, CE Costello, ... The FASEB Journal 28 (5), 1975, 2014 | 42 | 2014 |
Human glioma PKC‐ι and PKC‐βII phosphorylate cyclin‐dependent kinase activating kinase during the cell cycle M Acevedo‐Duncan, R Patel, S Whelan, E Bicaku Cell proliferation 35 (1), 23-36, 2002 | 40 | 2002 |
Overexpression of catalase diminishes oxidative cysteine modifications of cardiac proteins C Yao, JB Behring, D Shao, AL Sverdlov, SA Whelan, A Elezaby, X Yin, ... PLoS One 10 (12), e0144025, 2015 | 37 | 2015 |
In vitro hemocompatibility of thin film nitinol in stenotic flow conditions CP Kealey, SA Whelan, YJ Chun, CH Soojung, AW Tulloch, ... Biomaterials 31 (34), 8864-8871, 2010 | 37 | 2010 |
Programmable gene regulation for metabolic engineering using decoy transcription factor binding sites T Wang, N Tague, SA Whelan, MJ Dunlop Nucleic Acids Research 49 (2), 1163-1172, 2021 | 31 | 2021 |
Tryptophan metabolites suppress the Wnt pathway and promote adverse limb events in chronic kidney disease NV Arinze, W Yin, S Lotfollahzadeh, MA Napoleon, S Richards, JA Walker, ... The Journal of Clinical Investigation 132 (1), 2022 | 29 | 2022 |
Metabolites in a mouse cancer model enhance venous thrombogenicity through the aryl hydrocarbon receptor–tissue factor axis M Belghasem, D Roth, S Richards, MA Napolene, J Walker, W Yin, ... Blood, The Journal of the American Society of Hematology 134 (26), 2399-2413, 2019 | 29 | 2019 |