Stephen A Whelan, Ph.D.
Stephen A Whelan, Ph.D.
Biomedical Scientist, Cedars-Sinai, Precision Biomarker Laboratories
Потвърден имейл адрес: cshs.org - Начална страница
The metabolite α-ketoglutarate extends lifespan by inhibiting ATP synthase and TOR
RM Chin, X Fu, MY Pai, L Vergnes, H Hwang, G Deng, S Diep, ...
Nature 510 (7505), 397-401, 2014
O-GlcNAc: a regulatory post-translational modification
L Wells, SA Whelan, GW Hart
Biochemical and biophysical research communications 302 (3), 435-441, 2003
Regulation of the O-linked β-N-acetylglucosamine transferase by insulin signaling
SA Whelan, MD Lane, GW Hart
Journal of Biological Chemistry 283 (31), 21411-21417, 2008
Regulation of insulin receptor substrate 1 (IRS-1)/AKT kinase-mediated insulin signaling by O-linked β-N-acetylglucosamine in 3T3-L1 adipocytes
SA Whelan, WB Dias, L Thiruneelakantapillai, MD Lane, GW Hart
Journal of biological chemistry 285 (8), 5204-5211, 2010
Proteomic approaches to analyze the dynamic relationships between nucleocytoplasmic protein glycosylation and phosphorylation
SA Whelan, GW Hart
Circulation research 93 (11), 1047-1058, 2003
Biosynthetic machinery involved in aberrant glycosylation: promising targets for developing of drugs against cancer
A Vasconcelos-dos-Santos, IA Oliveira, MC Lucena, NR Mantuano, ...
Frontiers in oncology 5, 138, 2015
Epithelial mesenchymal transition induces aberrant glycosylation through hexosamine biosynthetic pathway activation
MC Lucena, P Carvalho-Cruz, JL Donadio, IA Oliveira, RM de Queiroz, ...
Journal of Biological Chemistry 291 (25), 12917-12929, 2016
Mass spectrometry (LC-MS/MS) site-mapping of N-glycosylated membrane proteins for breast cancer biomarkers
SA Whelan, M Lu, J He, W Yan, RE Saxton, KF Faull, JP Whitelegge, ...
Journal of proteome research 8 (8), 4151-4160, 2009
Comparative proteomics reveals dysregulated mitochondrial O-GlcNAcylation in diabetic hearts
J Ma, P Banerjee, SA Whelan, T Liu, AC Wei, G Ramirez-Correa, ...
Journal of proteome research 15 (7), 2254-2264, 2016
Mass spectrometry (LC–MS/MS) identified proteomic biosignatures of breast cancer in proximal fluid
SA Whelan, J He, M Lu, P Souda, RE Saxton, KF Faull, JP Whitelegge, ...
Journal of proteome research 11 (10), 5034-5045, 2012
Identification of O‐GlcNAc sites on proteins
SA Whelan, GW Hart
Methods in enzymology 415, 113-133, 2006
Proteomic-based biosignatures in breast cancer classification and prediction of therapeutic response
J He, SA Whelan, M Lu, D Shen, DU Chung, RE Saxton, KF Faull, ...
International journal of proteomics 2011, 2011
Characterization of the human NEK7 interactome suggests catalytic and regulatory properties distinct from those of NEK6
EE de Souza, GV Meirelles, BB Godoy, AM Perez, JHC Smetana, ...
Journal of proteome research 13 (9), 4074-4090, 2014
Does reversible cysteine oxidation link the Western diet to cardiac dysfunction?
JB Behring, V Kumar, SA Whelan, P Chauhan, DA Siwik, CE Costello, ...
The FASEB Journal 28 (5), 1975, 2014
Human glioma PKC‐ι and PKC‐βII phosphorylate cyclin‐dependent kinase activating kinase during the cell cycle
M Acevedo‐Duncan, R Patel, S Whelan, E Bicaku
Cell proliferation 35 (1), 23-36, 2002
Overexpression of catalase diminishes oxidative cysteine modifications of cardiac proteins
C Yao, JB Behring, D Shao, AL Sverdlov, SA Whelan, A Elezaby, X Yin, ...
PLoS One 10 (12), e0144025, 2015
In vitro hemocompatibility of thin film nitinol in stenotic flow conditions
CP Kealey, SA Whelan, YJ Chun, CH Soojung, AW Tulloch, ...
Biomaterials 31 (34), 8864-8871, 2010
Programmable gene regulation for metabolic engineering using decoy transcription factor binding sites
T Wang, N Tague, SA Whelan, MJ Dunlop
Nucleic Acids Research 49 (2), 1163-1172, 2021
Tryptophan metabolites suppress the Wnt pathway and promote adverse limb events in chronic kidney disease
NV Arinze, W Yin, S Lotfollahzadeh, MA Napoleon, S Richards, JA Walker, ...
The Journal of Clinical Investigation 132 (1), 2022
Metabolites in a mouse cancer model enhance venous thrombogenicity through the aryl hydrocarbon receptor–tissue factor axis
M Belghasem, D Roth, S Richards, MA Napolene, J Walker, W Yin, ...
Blood, The Journal of the American Society of Hematology 134 (26), 2399-2413, 2019
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Статии 1–20