| Transcription factor achaete scute-like 2 controls intestinal stem cell fate LG van der Flier, ME van Gijn, P Hatzis, P Kujala, A Haegebarth, ... Cell 136 (5), 903-912, 2009 | 829 | 2009 |
| Wnt signalling induces maturation of Paneth cells in intestinal crypts JH van Es, P Jay, A Gregorieff, ME van Gijn, S Jonkheer, P Hatzis, ... Nature cell biology 7 (4), 381-386, 2005 | 763 | 2005 |
| Plasticity and expanding complexity of the hepatic transcription factor network during liver development I Kyrmizi, P Hatzis, N Katrakili, F Tronche, FJ Gonzalez, I Talianidis Genes & development 20 (16), 2293-2305, 2006 | 356 | 2006 |
| Dynamics of enhancer-promoter communication during differentiation-induced gene activation P Hatzis, I Talianidis Molecular cell 10 (6), 1467-1477, 2002 | 301 | 2002 |
| Ascl2 acts as an R-spondin/Wnt-responsive switch to control stemness in intestinal crypts J Schuijers, JP Junker, M Mokry, P Hatzis, BK Koo, V Sasselli, ... Cell stem cell 16 (2), 158-170, 2015 | 300 | 2015 |
| Genome-wide pattern of TCF7L2/TCF4 chromatin occupancy in colorectal cancer cells P Hatzis, LG van der Flier, MA van Driel, V Guryev, F Nielsen, S Denissov, ... Molecular and cellular biology, 2008 | 289 | 2008 |
| Diabetes risk gene and Wnt effector Tcf7l2/TCF4 controls hepatic response to perinatal and adult metabolic demand SF Boj, JH van Es, M Huch, VSW Li, A José, P Hatzis, M Mokry, ... Cell 151 (7), 1595-1607, 2012 | 257 | 2012 |
| Wnt‐induced transcriptional activation is exclusively mediated by TCF/LEF J Schuijers, M Mokry, P Hatzis, E Cuppen, H Clevers The EMBO journal 33 (2), 146-156, 2014 | 210 | 2014 |
| Regulatory mechanisms controlling human hepatocyte nuclear factor 4α gene expression P Hatzis, I Talianidis Molecular and cellular biology 21 (21), 7320-7330, 2001 | 197 | 2001 |
| Selection of personalized patient therapy through the use of knowledge-based computational models that identify tumor-driving signal transduction pathways W Verhaegh, H van Ooijen, MA Inda, P Hatzis, R Versteeg, M Smid, ... Cancer research 74 (11), 2936-2945, 2014 | 124 | 2014 |
| The intracellular localization of deoxycytidine kinase P Hatzis, AS Al-Madhoon, M Jullig, TG Petrakis, S Eriksson, I Talianidis Journal of Biological Chemistry 273 (46), 30239-30243, 1998 | 124 | 1998 |
| The Tup1-Cyc8 protein complex can shift from a transcriptional co-repressor to a transcriptional co-activator RS Conlan, N Gounalaki, P Hatzis, D Tzamarias Journal of Biological Chemistry 274 (1), 205-210, 1999 | 112 | 1999 |
| Application of human liver organoids as a patient-derived primary model for HBV infection and related hepatocellular carcinoma E De Crignis, T Hossain, S Romal, F Carofiglio, P Moulos, MM Khalid, ... Elife 10, e60747, 2021 | 109 | 2021 |
| Systematic integration of RNA-Seq statistical algorithms for accurate detection of differential gene expression patterns P Moulos, P Hatzis Nucleic acids research 43 (4), e25-e25, 2015 | 107 | 2015 |
| Cooperative Synergy between NFAT and MyoD Regulates Myogenin Expression and Myogenesis∗ AS Armand, M Bourajjaj, S Martínez-Martínez, H el Azzouzi, ... Journal of Biological Chemistry 283 (43), 29004-29010, 2008 | 103 | 2008 |
| TCF4 and CDX2, major transcription factors for intestinal function, converge on the same cis-regulatory regions MP Verzi, P Hatzis, R Sulahian, J Philips, J Schuijers, H Shin, E Freed, ... Proceedings of the National Academy of Sciences 107 (34), 15157-15162, 2010 | 93 | 2010 |
| The leukemia-associated Mllt10/Af10-Dot1l are Tcf4/β-catenin coactivators essential for intestinal homeostasis T Mahmoudi, SF Boj, P Hatzis, VSW Li, N Taouatas, RGJ Vries, ... PLoS biology 8 (11), e1000539, 2010 | 92 | 2010 |
| Integrated genome-wide analysis of transcription factor occupancy, RNA polymerase II binding and steady-state RNA levels identify differentially regulated functional gene classes M Mokry, P Hatzis, J Schuijers, N Lansu, FP Ruzius, H Clevers, E Cuppen Nucleic acids research 40 (1), 148-158, 2012 | 87 | 2012 |
| The E3 ligase RNF43 inhibits Wnt signaling downstream of mutated β-catenin by sequestering TCF4 to the nuclear membrane A Loregger, M Grandl, R Mejías-Luque, M Allgäuer, K Degenhart, ... Science signaling 8 (393), ra90-ra90, 2015 | 85 | 2015 |
| Mitogen-activated protein kinase-mediated disruption of enhancer-promoter communication inhibits hepatocyte nuclear factor 4α expression P Hatzis, I Kyrmizi, I Talianidis Molecular and cellular biology 26 (19), 7017-7029, 2006 | 73 | 2006 |
