Mathew Garnett
Mathew Garnett
Wellcome Sanger Institute
Потвърден имейл адрес: sanger.ac.uk - Начална страница
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Позовавания
Позовавания
Година
Mutations of the BRAF gene in human cancer
H Davies, GR Bignell, C Cox, P Stephens, S Edkins, S Clegg, J Teague, ...
Nature 417 (6892), 949-954, 2002
111122002
Mechanism of activation of the RAF-ERK signaling pathway by oncogenic mutations of B-RAF
PTC Wan, MJ Garnett, SM Roe, S Lee, D Niculescu-Duvaz, VM Good, ...
Cell 116 (6), 855-867, 2004
28172004
Systematic identification of genomic markers of drug sensitivity in cancer cells
MJ Garnett, EJ Edelman, SJ Heidorn, CD Greenman, A Dastur, KW Lau, ...
Nature 483 (7391), 570-575, 2012
21182012
Prospective derivation of a living organoid biobank of colorectal cancer patients
M van de Wetering, HE Francies, JM Francis, G Bounova, F Iorio, A Pronk, ...
Cell 161 (4), 933-945, 2015
13352015
Genomics of Drug Sensitivity in Cancer (GDSC): a resource for therapeutic biomarker discovery in cancer cells
W Yang, J Soares, P Greninger, EJ Edelman, H Lightfoot, S Forbes, ...
Nucleic acids research 41 (D1), D955-D961, 2012
13222012
A landscape of pharmacogenomic interactions in cancer
F Iorio, TA Knijnenburg, DJ Vis, GR Bignell, MP Menden, M Schubert, ...
Cell 166 (3), 740-754, 2016
10452016
Guilty as charged: B-RAF is a human oncogene
MJ Garnett, R Marais
Cancer cell 6 (4), 313-319, 2004
10372004
Human primary liver cancer–derived organoid cultures for disease modeling and drug screening
L Broutier, G Mastrogiovanni, MMA Verstegen, HE Francies, LM Gavarró, ...
Nature medicine 23 (12), 1424-1435, 2017
5582017
Prioritization of cancer therapeutic targets using CRISPR–Cas9 screens
FM Behan, F Iorio, G Picco, E Gonçalves, CM Beaver, G Migliardi, ...
Nature 568 (7753), 511-516, 2019
4652019
Wild-type and mutant B-RAF activate C-RAF through distinct mechanisms involving heterodimerization
MJ Garnett, S Rana, H Paterson, D Barford, R Marais
Molecular cell 20 (6), 963-969, 2005
4342005
MED12 controls the response to multiple cancer drugs through regulation of TGF-β receptor signaling
S Huang, M Hölzel, T Knijnenburg, A Schlicker, P Roepman, U McDermott, ...
Cell 151 (5), 937-950, 2012
3972012
Machine learning prediction of cancer cell sensitivity to drugs based on genomic and chemical properties
MP Menden, F Iorio, M Garnett, U McDermott, CH Benes, PJ Ballester, ...
PLoS one 8 (4), e61318, 2013
3792013
ETV6-NTRK3 gene fusions and trisomy 11 establish a histogenetic link between mesoblastic nephroma and congenital fibrosarcoma
SR Knezevich, MJ Garnett, TJ Pysher, JB Beckwith, PE Grundy, ...
Cancer research 58 (22), 5046-5048, 1998
3631998
A biobank of breast cancer explants with preserved intra-tumor heterogeneity to screen anticancer compounds
A Bruna, OM Rueda, W Greenwood, AS Batra, M Callari, RN Batra, ...
Cell 167 (1), 260-274. e22, 2016
3122016
UBE2S elongates ubiquitin chains on APC/C substrates to promote mitotic exit
MJ Garnett, J Mansfeld, C Godwin, T Matsusaka, J Wu, P Russell, J Pines, ...
Nature cell biology 11 (11), 1363-1369, 2009
2492009
Mutations of C-RAF are rare in human cancer because C-RAF has a low basal kinase activity compared with B-RAF
V Emuss, M Garnett, C Mason, R Marais
Cancer research 65 (21), 9719-9726, 2005
2222005
Characterizing mutational signatures in human cancer cell lines reveals episodic APOBEC mutagenesis
M Petljak, LB Alexandrov, JS Brammeld, S Price, DC Wedge, ...
Cell 176 (6), 1282-1294. e20, 2019
1762019
Perturbation-response genes reveal signaling footprints in cancer gene expression
M Schubert, B Klinger, M Klünemann, A Sieber, F Uhlitz, S Sauer, ...
Nature communications 9 (1), 1-11, 2018
1482018
Targeting the RB-E2F pathway in breast cancer
J Johnson, B Thijssen, U McDermott, M Garnett, LFA Wessels, R Bernards
Oncogene 35 (37), 4829-4835, 2016
1472016
Integration of genomic, transcriptomic and proteomic data identifies two biologically distinct subtypes of invasive lobular breast cancer
M Michaut, SF Chin, I Majewski, TM Severson, T Bismeijer, L De Koning, ...
Scientific reports 6 (1), 1-13, 2016
1462016
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