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Krushna Chandra Patra
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The pentose phosphate pathway and cancer
KC Patra, N Hay
Trends in biochemical sciences 39 (8), 347-354, 2014
13292014
Hexokinase 2 is required for tumor initiation and maintenance and its systemic deletion is therapeutic in mouse models of cancer
KC Patra, Q Wang, PT Bhaskar, L Miller, Z Wang, W Wheaton, N Chandel, ...
Cancer cell 24 (2), 213-228, 2013
8122013
Hexokinase-2 depletion inhibits glycolysis and induces oxidative phosphorylation in hepatocellular carcinoma and sensitizes to metformin
D DeWaal, V Nogueira, AR Terry, KC Patra, SM Jeon, G Guzman, J Au, ...
Nature communications 9 (1), 446, 2018
3942018
TAS-120 overcomes resistance to ATP-competitive FGFR inhibitors in patients with FGFR2 fusion–positive intrahepatic cholangiocarcinoma
L Goyal, L Shi, LY Liu, F Fece de la Cruz, JK Lennerz, S Raghavan, ...
Cancer discovery 9 (8), 1064-1079, 2019
2792019
Mutant GNAS drives pancreatic tumourigenesis by inducing PKA-mediated SIK suppression and reprogramming lipid metabolism
KC Patra, Y Kato, Y Mizukami, S Widholz, M Boukhali, I Revenco, ...
Nature cell biology 20 (7), 811-822, 2018
1442018
Diversity of precursor lesions for pancreatic cancer: the genetics and biology of intraductal papillary mucinous neoplasm
KC Patra, N Bardeesy, Y Mizukami
Clinical and translational gastroenterology 8 (4), e86, 2017
1162017
Microbial transformation of tannin-rich substrate to gallic acid through co-culture method
R Banerjee, G Mukherjee, KC Patra
Bioresource Technology 96 (8), 949-953, 2005
1072005
Kras and Tp53 mutations cause cholangiocyte-and hepatocyte-derived cholangiocarcinoma
MA Hill, WB Alexander, B Guo, Y Kato, K Patra, MR O'Dell, MN McCall, ...
Cancer research 78 (16), 4445-4451, 2018
902018
mTORC1 hyperactivity inhibits serum deprivation-induced apoptosis via increased hexokinase II and GLUT1 expression, sustained Mcl-1 expression, and glycogen synthase kinase 3β …
PT Bhaskar, V Nogueira, KC Patra, SM Jeon, Y Park, RB Robey, N Hay
Molecular and cellular biology 29 (18), 5136-5147, 2009
642009
DDB2 suppresses epithelial-to-mesenchymal transition in colon cancer
N Roy, PV Bommi, UG Bhat, S Bhattacharjee, I Elangovan, J Li, KC Patra, ...
Cancer research 73 (12), 3771-3782, 2013
592013
Hexokinase 2 as oncotarget
KC Patra, N Hay
Oncotarget 4 (11), 1862, 2013
582013
Selective eradication of cancer displaying hyperactive Akt by exploiting the metabolic consequences of Akt activation
V Nogueira, KC Patra, N Hay
Elife 7, e32213, 2018
402018
A non-catalytic scaffolding activity of hexokinase 2 contributes to EMT and metastasis
CS Blaha, G Ramakrishnan, SM Jeon, V Nogueira, H Rho, S Kang, ...
Nature Communications 13 (1), 899, 2022
382022
REDD1 loss reprograms lipid metabolism to drive progression of RAS mutant tumors
S Qiao, SB Koh, V Vivekanandan, D Salunke, KC Patra, E Zaganjor, ...
Genes & development 34 (11-12), 751-766, 2020
342020
AMPK-mediated lysosome biogenesis in lung cancer growth
KC Patra, VK Weerasekara, N Bardeesy
Cell metabolism 29 (2), 238-240, 2019
162019
Oncogenic PKA signaling increases c-MYC protein expression through multiple targetable mechanisms
GKL Chan, S Maisel, YC Hwang, BC Pascual, RRB Wolber, P Vu, ...
Elife 12, e69521, 2023
132023
Author Correction: Hexokinase-2 depletion inhibits glycolysis and induces oxidative phosphorylation in hepatocellular carcinoma and sensitizes to metformin
D DeWaal, V Nogueira, AR Terry, KC Patra, SM Jeon, G Guzman, J Au, ...
Nature Communications 9, 2018
132018
Systemic Akt1 deletion after tumor onset in p53−/− mice increases lifespan and regresses thymic lymphoma emulating p53 restoration
WN Yu, V Nogueira, A Sobhakumari, KC Patra, PT Bhaskar, N Hay
Cell reports 12 (4), 610-621, 2015
112015
EGFR Pathway links amino acid levels and induction of macropinocytosis
VK Weerasekara, KC Patra, N Bardeesy
Developmental Cell 50 (3), 261-263, 2019
92019
A cell size theory of aging
KC Patra, N Bardeesy
Developmental Cell 45 (6), 665-666, 2018
42018
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