| Inhibition of ceramide synthesis ameliorates glucocorticoid-, saturated-fat-, and obesity-induced insulin resistance WL Holland, JT Brozinick, LP Wang, ED Hawkins, KM Sargent, Y Liu, ... Cell metabolism 5 (3), 167-179, 2007 | 1406 | 2007 |
| Excess lipid availability increases mitochondrial fatty acid oxidative capacity in muscle: evidence against a role for reduced fatty acid oxidation in lipid-induced insulin … N Turner, CR Bruce, SM Beale, KL Hoehn, T So, MS Rolph, GJ Cooney Diabetes 56 (8), 2085-2092, 2007 | 654 | 2007 |
| Erk2 phosphorylation of Drp1 promotes mitochondrial fission and MAPK-driven tumor growth JA Kashatus, A Nascimento, LJ Myers, A Sher, FL Byrne, KL Hoehn, ... Molecular cell 57 (3), 537-551, 2015 | 651 | 2015 |
| Insulin resistance is a cellular antioxidant defense mechanism KL Hoehn, AB Salmon, C Hohnen-Behrens, N Turner, AJ Hoy, ... Proceedings of the National Academy of Sciences 106 (42), 17787-17792, 2009 | 618 | 2009 |
| Autophagy is required for exercise training-induced skeletal muscle adaptation and improvement of physical performance VA Lira, M Okutsu, M Zhang, NP Greene, RC Laker, DS Breen, KL Hoehn, ... The FASEB Journal 27 (10), 4184, 2013 | 528 | 2013 |
| Regulation of insulin action by ceramide: dual mechanisms linking ceramide accumulation to the inhibition of Akt/protein kinase B S Stratford, KL Hoehn, F Liu, SA Summers Journal of Biological Chemistry 279 (35), 36608-36615, 2004 | 526 | 2004 |
| Mitochondrial division is requisite to RAS-induced transformation and targeted by oncogenic MAPK pathway inhibitors MN Serasinghe, SY Wieder, TT Renault, R Elkholi, JJ Asciolla, JL Yao, ... Molecular cell 57 (3), 521-536, 2015 | 380 | 2015 |
| Lipid mediators of insulin resistance WL Holland, TA Knotts, JA Chavez, LP Wang, KL Hoehn, SA Summers Nutrition reviews 65 (suppl_1), S39-S46, 2007 | 374 | 2007 |
| IRS1-independent defects define major nodes of insulin resistance KL Hoehn, C Hohnen-Behrens, A Cederberg, LE Wu, N Turner, T Yuasa, ... Cell metabolism 7 (5), 421-433, 2008 | 354 | 2008 |
| Continued clearance of apoptotic cells critically depends on the phagocyte Ucp2 protein D Park, CZ Han, MR Elliott, JM Kinchen, PC Trampont, S Das, S Collins, ... Nature 477 (7363), 220-224, 2011 | 270 | 2011 |
| Identification of a novel mitochondrial uncoupler that does not depolarize the plasma membrane BM Kenwood, JL Weaver, A Bajwa, IK Poon, FL Byrne, BA Murrow, ... Molecular metabolism 3 (2), 114-123, 2014 | 260 | 2014 |
| A novel MitoTimer reporter gene for mitochondrial content, structure, stress, and damage in vivo RC Laker, P Xu, KA Ryall, A Sujkowski, BM Kenwood, KH Chain, ... Journal of Biological Chemistry 289 (17), 12005-12015, 2014 | 252 | 2014 |
| Exercise prevents maternal high-fat diet–induced hypermethylation of the Pgc-1α gene and age-dependent metabolic dysfunction in the offspring RC Laker, TS Lillard, M Okutsu, M Zhang, KL Hoehn, JJ Connelly, Z Yan Diabetes 63 (5), 1605-1611, 2014 | 245 | 2014 |
| Pigment epithelium-derived factor contributes to insulin resistance in obesity S Crowe, LE Wu, C Economou, SM Turpin, M Matzaris, KL Hoehn, ... Cell metabolism 10 (1), 40-47, 2009 | 222 | 2009 |
| Regulator of fatty acid metabolism, acetyl coenzyme a carboxylase 1, controls T cell immunity JE Lee, MC Walsh, KL Hoehn, DE James, EJ Wherry, Y Choi The Journal of Immunology 192 (7), 3190-3199, 2014 | 196 | 2014 |
| Acute or chronic upregulation of mitochondrial fatty acid oxidation has no net effect on whole-body energy expenditure or adiposity KL Hoehn, N Turner, MM Swarbrick, D Wilks, E Preston, Y Phua, H Joshi, ... Cell metabolism 11 (1), 70-76, 2010 | 196 | 2010 |
| Small molecule mitochondrial uncouplers and their therapeutic potential: miniperspective ES Childress, SJ Alexopoulos, KL Hoehn, WL Santos Journal of Medicinal Chemistry 61 (11), 4641-4655, 2017 | 143 | 2017 |
| CaMKII-mediated phosphorylation of the myosin motor Myo1c is required for insulin-stimulated GLUT4 translocation in adipocytes MF Yip, G Ramm, M Larance, KL Hoehn, MC Wagner, M Guilhaus, ... Cell metabolism 8 (5), 384-398, 2008 | 140 | 2008 |
| Impaired enolase 1 glycolytic activity restrains effector functions of tumor-infiltrating CD8+ T cells LF Gemta, PJ Siska, ME Nelson, X Gao, X Liu, JW Locasale, H Yagita, ... Science Immunology 4 (31), eaap9520, 2019 | 129 | 2019 |
| A selective inhibitor of ceramide synthase 1 reveals a novel role in fat metabolism N Turner, XY Lim, HD Toop, B Osborne, AE Brandon, EN Taylor, ... Nature communications 9 (1), 3165, 2018 | 129 | 2018 |
