| Accelerated aging and failure to segregate damaged proteins in Sir2 mutants can be suppressed by overproducing the protein aggregation-remodeling factor Hsp104p N Erjavec, L Larsson, J Grantham, T Nyström Genes & development 21 (19), 2410-2421, 2007 | 430 | 2007 |
| The polarisome is required for segregation and retrograde transport of protein aggregates B Liu, L Larsson, A Caballero, X Hao, D Öling, J Grantham, T Nyström Cell 140 (2), 257-267, 2010 | 382 | 2010 |
| Eukaryotic type II chaperonin CCT interacts with actin through specific subunits O Llorca, EA McCormack, G Hynes, J Grantham, J Cordell, JL Carrascosa, ... Nature 402 (6762), 693-696, 1999 | 318 | 1999 |
| Eukaryotic chaperonin CCT stabilizes actin and tubulin folding intermediates in open quasi‐native conformations O Llorca, J Martín‐Benito, M Ritco‐Vonsovici, J Grantham, GM Hynes, ... The EMBO journal, 2000 | 253 | 2000 |
| Activities of the chaperonin containing TCP-1 (CCT): implications for cell cycle progression and cytoskeletal organisation. KI Brackley, J Grantham Cell Stress and Chaperones 14 (1), 23-31, 2009 | 178 | 2009 |
| The ‘sequential allosteric ring’mechanism in the eukaryotic chaperonin‐assisted folding of actin and tubulin O Llorca, J Martín‐Benito, J Grantham, M Ritco‐Vonsovici, KR Willison, ... The EMBO journal, 2001 | 167 | 2001 |
| Substantial CCT activity is required for cell cycle progression and cytoskeletal organization in mammalian cells J Grantham, KI Brackley, KR Willison Experimental cell research 312 (12), 2309-2324, 2006 | 141 | 2006 |
| Segregation of protein aggregates involves actin and the polarity machinery B Liu, L Larsson, V Franssens, X Hao, SM Hill, V Andersson, D Höglund, ... Cell 147 (5), 959-961, 2011 | 102 | 2011 |
| Essential Genetic Interactors of SIR2 Required for Spatial Sequestration and Asymmetrical Inheritance of Protein Aggregates J Song, Q Yang, J Yang, L Larsson, X Hao, X Zhu, S Malmgren-Hill, ... PLoS genetics 10 (7), e1004539, 2014 | 90 | 2014 |
| The role of the molecular chaperone CCT in protein folding and mediation of cytoskeleton-associated processes: implications for cancer cell biology J Vallin, J Grantham Cell Stress and Chaperones 24 (1), 17-27, 2019 | 83 | 2019 |
| Subunits of the chaperonin CCT interact with F-actin and influence cell shape and cytoskeletal assembly KI Brackley, J Grantham Experimental cell research 316 (4), 543-553, 2010 | 82 | 2010 |
| Electron microscopy and 3D reconstructions reveal that human ATM kinase uses an arm-like domain to clamp around double-stranded DNA O Llorca, A Rivera-Calzada, J Grantham, KR Willison Oncogene 22 (25), 3867-3874, 2003 | 82 | 2003 |
| The molecular chaperone CCT/TRiC: an essential component of proteostasis and a potential modulator of protein aggregation J Grantham Frontiers in Genetics 11, 506143, 2020 | 78 | 2020 |
| Eukaryotic chaperonin containing T-complex polypeptide 1 interacts with filamentous actin and reduces the initial rate of actin polymerization in vitro J Grantham, LW Ruddock, A Roobol, MJ Carden Cell Stress & Chaperones 7 (3), 235, 2002 | 58 | 2002 |
| The inter‐ring arrangement of the cytosolic chaperonin CCT J Martín‐Benito, J Grantham, J Boskovic, KI Brackley, JL Carrascosa, ... EMBO reports 8 (3), 252-257, 2007 | 52 | 2007 |
| Partial occlusion of both cavities of the eukaryotic chaperonin with antibody has no effect upon the rates of β-actin or α-tubulin folding J Grantham, O Llorca, JM Valpuesta, KR Willison Journal of Biological Chemistry 275 (7), 4587-4591, 2000 | 45 | 2000 |
| Disassembly of the cytosolic chaperonin in mammalian cell extracts at intracellular levels of K+ and ATP A Roobol, J Grantham, HC Whitaker, MJ Carden Journal of Biological Chemistry 274 (27), 19220-19227, 1999 | 41 | 1999 |
| A novel function of the monomeric CCTε subunit connects the serum response factor pathway to chaperone-mediated actin folding KL Elliott, A Svanström, M Spiess, R Karlsson, J Grantham Molecular biology of the cell 26 (15), 2801-2809, 2015 | 31 | 2015 |
| Over-expression analysis of all eight subunits of the molecular chaperone CCT in mammalian cells reveals a novel function for CCTdelta M Spiess, M Echbarthi, A Svanström, R Karlsson, J Grantham Journal of molecular biology 427 (17), 2757-2764, 2015 | 30 | 2015 |
| Interactions between monomeric CCTδ and p150Glued: a novel function for CCTδ at the cell periphery distinct from the protein folding activity of the molecular chaperone CCT M Echbarthi, J Vallin, J Grantham Experimental cell research 370 (1), 137-149, 2018 | 27 | 2018 |
