Thomas Hartung
Thomas Hartung
Chair for Evidence-based Toxicology, Johns Hopkins University
Verified email at - Homepage
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CD36 is a sensor of diacylglycerides
K Hoebe, P Georgel, S Rutschmann, X Du, S Mudd, K Crozat, S Sovath, ...
Nature 433 (7025), 523-527, 2005
Toll-like receptor 2 suppresses immunity against Candida albicans through induction of IL-10 and regulatory T cells
MG Netea, R Sutmuller, C Hermann, CAA Van der Graaf, ...
The Journal of Immunology 172 (6), 3712-3718, 2004
Lipoteichoic acid (LTA) of Streptococcus pneumoniaeand Staphylococcus aureus activates immune cells via Toll-like receptor (TLR)-2, lipopolysaccharide-binding protein (LBP …
NWJ Schröder, S Morath, C Alexander, L Hamann, T Hartung, ...
Journal of biological chemistry 278 (18), 15587-15594, 2003
Innate immunity in Arabidopsis thaliana: lipopolysaccharides activate nitric oxide synthase (NOS) and induce defense genes
D Zeidler, U Zähringer, I Gerber, I Dubery, T Hartung, W Bors, P Hutzler, ...
Proceedings of the National Academy of Sciences 101 (44), 15811-15816, 2004
Toxicology for the twenty-first century
T Hartung
Nature 460 (7252), 208-212, 2009
Structure–Function Relationship of Cytokine Induction by Lipoteichoic Acid fromStaphylococcus aureus
S Morath, A Geyer, T Hartung
The Journal of experimental medicine 193 (3), 393-398, 2001
Membrane sorting of toll-like receptor (TLR)-2/6 and TLR2/1 heterodimers at the cell surface determines heterotypic associations with CD36 and intracellular targeting
M Triantafilou, FGJ Gamper, RM Haston, MA Mouratis, S Morath, ...
Journal of Biological Chemistry 281 (41), 31002-31011, 2006
Enhanced antiinflammatory capacity of a Lactobacillus plantarum mutant synthesizing modified teichoic acids
C Grangette, S Nutten, E Palumbo, S Morath, C Hermann, J Dewulf, B Pot, ...
Proceedings of the National Academy of Sciences 102 (29), 10321-10326, 2005
Prevalence of Borrelia burgdorferi Sensu Lato Genospecies in Ixodes ricinus Ticks in Europe: a Metaanalysis
C Rauter, T Hartung
Applied and environmental microbiology 71 (11), 7203-7216, 2005
Guidance on good cell culture practice: a report of the second ECVAM task force on good cell culture practice
S Coecke, M Balls, G Bowe, J Davis, G Gstraunthaler, T Hartung, R Hay, ...
Alternatives to Laboratory Animals 33 (3), 261-287, 2005
Interleukin-10 counterregulates proinflammatory cytokine-induced inhibition of neutrophil apoptosis during severe sepsis
M Keel, U Ungethüm, U Steckholzer, E Niederer, T Hartung, O Trentz, ...
Blood, The Journal of the American Society of Hematology 90 (9), 3356-3363, 1997
Lipopolysaccharide and ceramide docking to CD14 provokes ligand‐specific receptor clustering in rafts
A Pfeiffer, A Böttcher, E Orsó, M Kapinsky, P Nagy, A Bodnár, I Spreitzer, ...
European journal of immunology 31 (11), 3153-3164, 2001
The role of toll-like receptors (TLRs) in bacteria-induced maturation of murine dendritic cells (DCS): peptidoglycan and lipoteichoic acid are inducers of DC maturation and …
KS Michelsen, A Aicher, M Mohaupt, T Hartung, S Dimmeler, ...
Journal of Biological Chemistry 276 (28), 25680-25686, 2001
Induction of cross-tolerance by lipopolysaccharide and highly purified lipoteichoic acid via different Toll-like receptors independent of paracrine mediators
MD Lehner, S Morath, KS Michelsen, RR Schumann, T Hartung
The Journal of Immunology 166 (8), 5161-5167, 2001
A modular approach to the ECVAM principles on test validity
T Hartung, S Bremer, S Casati, S Coecke, R Corvi, S Fortaner, L Gribaldo, ...
Alternatives to Laboratory Animals 32 (5), 467-472, 2004
Multi-tissue interactions in an integrated three-tissue organ-on-a-chip platform
A Skardal, SV Murphy, M Devarasetty, I Mead, HW Kang, YJ Seol, ...
Scientific reports 7 (1), 1-16, 2017
Outcome prediction by traditional and new markers of inflammation in patients with sepsis
M Oberhoffer, H Vogelsang, S Rußwurm, T Hartung, K Reinhart
Walter de Gruyter 37 (3), 363-368, 1999
L-ficolin specifically binds to lipoteichoic acid, a cell wall constituent of Gram-positive bacteria, and activates the lectin pathway of complement
NJ Lynch, S Roscher, T Hartung, S Morath, M Matsushita, DN Maennel, ...
The Journal of Immunology 172 (2), 1198-1202, 2004
Synthetic Lipoteichoic Acid from Staphylococcus aureus Is a Potent Stimulus of Cytokine Release
S Morath, A Stadelmaier, A Geyer, RR Schmidt, T Hartung
The Journal of experimental medicine 195 (12), 1635-1640, 2002
Effect of granulocyte colony-stimulating factor treatment on ex vivo blood cytokine response in human volunteers
T Hartung, WD Docke, F Gantner, G Krieger, A Sauer, P Stevens, HD Volk, ...
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