Следене
John Dominy
John Dominy
Novartis Institute of Biomedical Research
Потвърден имейл адрес: novartis.com
Заглавие
Позовавания
Позовавания
Година
Mammalian cysteine metabolism: new insights into regulation of cysteine metabolism
MH Stipanuk, JE Dominy Jr, JI Lee, RM Coloso
The Journal of nutrition 136 (6), 1652S-1659S, 2006
5572006
The cAMP/PKA pathway rapidly activates SIRT1 to promote fatty acid oxidation independently of changes in NAD+
Z Gerhart-Hines, JE Dominy, SM Blättler, MP Jedrychowski, AS Banks, ...
Molecular cell 44 (6), 851-863, 2011
3612011
The deacetylase Sirt6 activates the acetyltransferase GCN5 and suppresses hepatic gluconeogenesis
JE Dominy, Y Lee, MP Jedrychowski, H Chim, MJ Jurczak, JP Camporez, ...
Molecular cell 48 (6), 900-913, 2012
3052012
Mitochondrial biogenesis through activation of nuclear signaling proteins
JE Dominy, P Puigserver
Cold Spring Harbor perspectives in biology 5 (7), a015008, 2013
2832013
The sirtuin family’s role in aging and age-associated pathologies
JA Hall, JE Dominy, Y Lee, P Puigserver
The Journal of clinical investigation 123 (3), 973-979, 2013
2702013
Cyclin D1–Cdk4 controls glucose metabolism independently of cell cycle progression
Y Lee, JE Dominy, YJ Choi, M Jurczak, N Tolliday, JP Camporez, H Chim, ...
Nature 510 (7506), 547-551, 2014
2502014
Cysteine dioxygenase: a robust system for regulation of cellular cysteine levels
MH Stipanuk, I Ueki, JE Dominy, CR Simmons, LL Hirschberger
Amino acids 37, 55-63, 2009
2362009
Oleic acid stimulates complete oxidation of fatty acids through protein kinase A-dependent activation of SIRT1-PGC1α complex
JH Lim, Z Gerhart-Hines, JE Dominy, Y Lee, S Kim, M Tabata, YK Xiang, ...
Journal of Biological Chemistry 288 (10), 7117-7126, 2013
2302013
Nutrient-dependent regulation of PGC-1α's acetylation state and metabolic function through the enzymatic activities of Sirt1/GCN5
JE Dominy Jr, Y Lee, Z Gerhart-Hines, P Puigserver
Biochimica et biophysica acta (BBA)-proteins and proteomics 1804 (8), 1676-1683, 2010
2212010
The cytoprotective role of taurine in exercise-induced muscle injury
R Dawson, Jr, M Biasetti, S Messina, J Dominy
Amino acids 22 (4), 309-324, 2002
2202002
Discovery and characterization of a second mammalian thiol dioxygenase, cysteamine dioxygenase
JE Dominy, CR Simmons, LL Hirschberger, J Hwang, RM Coloso, ...
Journal of Biological Chemistry 282 (35), 25189-25198, 2007
1792007
Selective chemical inhibition of PGC-1α gluconeogenic activity ameliorates type 2 diabetes
K Sharabi, H Lin, CDJ Tavares, JE Dominy, JP Camporez, RJ Perry, ...
Cell 169 (1), 148-160. e15, 2017
1742017
Synthesis of amino acid cofactor in cysteine dioxygenase is regulated by substrate and represents a novel post-translational regulation of activity
JE Dominy, J Hwang, S Guo, LL Hirschberger, S Zhang, MH Stipanuk
Journal of Biological Chemistry 283 (18), 12188-12201, 2008
1422008
New Roles for Cysteine and Transsulfuration Enzymes: Production of H2S, a Neuromodulator and Smooth Muscle Relaxant
JE Dominy, MH Stipanuk
Nutrition reviews 62 (9), 348-353, 2004
1242004
Thiol dioxygenases: unique families of cupin proteins
MH Stipanuk, CR Simmons, P Andrew Karplus, JE Dominy
Amino acids 41, 91-102, 2011
1232011
Identification and characterization of bacterial cysteine dioxygenases: a new route of cysteine degradation for eubacteria
JE Dominy Jr, CR Simmons, PA Karplus, AM Gehring, MH Stipanuk
Journal of bacteriology 188 (15), 5561-5569, 2006
1192006
HepG2/C3A cells respond to cysteine deprivation by induction of the amino acid deprivation/integrated stress response pathway
JI Lee, JE Dominy Jr, AK Sikalidis, LL Hirschberger, W Wang, ...
Physiological genomics 33 (2), 218-229, 2008
1162008
Genetic inhibition of hepatic acetyl-CoA carboxylase activity increases liver fat and alters global protein acetylation
JDY Chow, RT Lawrence, ME Healy, JE Dominy, JA Liao, DS Breen, ...
Molecular metabolism 3 (4), 419-431, 2014
1132014
Regulation of cysteine dioxygenase degradation is mediated by intracellular cysteine levels and the ubiquitin–26 S proteasome system in the living rat
JE Dominy Jr, LL Hirschberger, RM Coloso, MH Stipanuk
Biochemical Journal 394 (1), 267-273, 2006
982006
A Putative Fe2+-Bound Persulfenate Intermediate in Cysteine Dioxygenase
CR Simmons, K Krishnamoorthy, SL Granett, DJ Schuller, JE Dominy Jr, ...
Biochemistry 47 (44), 11390-11392, 2008
962008
Системата не може да изпълни операцията сега. Опитайте отново по-късно.
Статии 1–20