| Activation of the Protein Deacetylase SIRT6 by Long-chain Fatty Acids and Widespread Deacylation by Mammalian Sirtuins*♦ JL Feldman, J Baeza, JM Denu Journal of Biological Chemistry 288 (43), 31350-31356, 2013 | 650 | 2013 |
| Metabolic regulation of histone post-translational modifications J Fan, KA Krautkramer, JL Feldman, JM Denu ACS chemical biology 10 (1), 95-108, 2015 | 321 | 2015 |
| Structure and biochemical functions of SIRT6 PW Pan, JL Feldman, MK Devries, A Dong, AM Edwards, JM Denu Journal of Biological Chemistry 286 (16), 14575-14587, 2011 | 312 | 2011 |
| The deacetylase Sirt6 activates the acetyltransferase GCN5 and suppresses hepatic gluconeogenesis JE Dominy, Y Lee, MP Jedrychowski, H Chim, MJ Jurczak, JP Camporez, ... Molecular cell 48 (6), 900-913, 2012 | 306 | 2012 |
| Sirtuin catalysis and regulation JL Feldman, KE Dittenhafer-Reed, JM Denu Journal of Biological Chemistry 287 (51), 42419-42427, 2012 | 278 | 2012 |
| Kinetic and Structural Basis for Acyl-Group Selectivity and NAD+ Dependence in Sirtuin-Catalyzed Deacylation JL Feldman, KE Dittenhafer-Reed, N Kudo, JN Thelen, A Ito, M Yoshida, ... Biochemistry 54 (19), 3037-3050, 2015 | 186 | 2015 |
| Nitration of Hsp90 induces cell death MC Franco, Y Ye, CA Refakis, JL Feldman, AL Stokes, M Basso, ... Proceedings of the National Academy of Sciences 110 (12), E1102-E1111, 2013 | 158 | 2013 |
| Identification of and molecular basis for SIRT6 loss-of-function point mutations in cancer S Kugel, JL Feldman, MA Klein, DM Silberman, C Sebastián, C Mermel, ... Cell reports 13 (3), 479-488, 2015 | 79 | 2015 |
| Structural basis of improved second-generation 3-nitro-tyrosine tRNA synthetases RB Cooley, JL Feldman, CM Driggers, TA Bundy, AL Stokes, PA Karplus, ... Biochemistry 53 (12), 1916-1924, 2014 | 68 | 2014 |
| Catalysis and mechanistic insights into sirtuin activation KE Dittenhafer‐Reed, JL Feldman, JM Denu Chembiochem 12 (2), 281-289, 2011 | 48 | 2011 |
| Multivalent interactions drive nucleosome binding and efficient chromatin deacetylation by SIRT6 WH Liu, J Zheng, JL Feldman, MA Klein, VI Kuznetsov, CL Peterson, ... Nature Communications 11 (1), 5244, 2020 | 30 | 2020 |
| Yeast sirtuin family members maintain transcription homeostasis to ensure genome stability JL Feldman, CL Peterson Cell reports 27 (10), 2978-2989. e5, 2019 | 25 | 2019 |
| Cryo-EM structure of the human Sirtuin 6–nucleosome complex US Chio, O Rechiche, AR Bryll, J Zhu, EM Leith, JL Feldman, CL Peterson, ... Science Advances 9 (15), eadf7586, 2023 | 12 | 2023 |
| Scalable and purification-free synthesis of a myristoylated fluorogenic sirtuin substrate I Galleano, J Nielsen, AS Madsen, CA Olsen Synlett 28 (16), 2169-2173, 2017 | 7 | 2017 |
| SWI/SNF antagonizes SIR heterochromatin to promote transcription of genes expressed during mitotic exit in Saccharomyces cerevisiae M Rege, JL Feldman, NL Adkins, CL Peterson bioRxiv, 2020.03. 24.006205, 2020 | | 2020 |
