Следене
David D. Weis
David D. Weis
Senior Principal Scientist, Bristol Myers Squibb
Потвърден имейл адрес: bms.com
Заглавие
Позовавания
Позовавания
Година
Recommendations for performing, interpreting and reporting hydrogen deuterium exchange mass spectrometry (HDX-MS) experiments
GR Masson, JE Burke, NG Ahn, GS Anand, C Borchers, S Brier, ...
Nature Methods 16 (7), 595, 2019
5272019
Semi-automated data processing of hydrogen exchange mass spectra using HX-Express
DD Weis, JR Engen, IJ Kass
Journal of the American Society for Mass Spectrometry 17, 1700-1703, 2006
2862006
Identification and characterization of EX1 kinetics in H/D exchange mass spectrometry by peak width analysis
DD Weis, TE Wales, JR Engen, M Hotchko, LF Ten Eyck
Journal of the American Society for Mass Spectrometry 17, 1498-1509, 2006
2512006
Water content and morphology of sodium chloride aerosol particles
DD Weis, GE Ewing
Journal of Geophysical Research: Atmospheres 104 (D17), 21275-21285, 1999
1701999
Analysis of overlapped and noisy hydrogen/deuterium exchange mass spectra
M Guttman, DD Weis, JR Engen, KK Lee
Journal of The American Society for Mass Spectrometry 24 (12), 1906-1912, 2013
1692013
Structural basis for activation of calcineurin by calmodulin
J Rumi-Masante, FI Rusinga, TE Lester, TB Dunlap, TD Williams, ...
Journal of molecular biology 415 (2), 307-317, 2012
1332012
Effects of salts from the Hofmeister series on the conformational stability, aggregation propensity, and local flexibility of an IgG1 monoclonal antibody
R Majumdar, P Manikwar, JM Hickey, HS Samra, HA Sathish, SM Bishop, ...
Biochemistry 52 (19), 3376-3389, 2013
1212013
Infrared spectroscopic signatures of (NH4) 2SO4 aerosols
DD Weis, GE Ewing
Journal of Geophysical Research: Atmospheres 101 (D13), 18709-18720, 1996
1141996
Correlating excipient effects on conformational and storage stability of an IgG1 monoclonal antibody with local dynamics as measured by hydrogen/deuterium‐exchange mass …
P Manikwar, R Majumdar, JM Hickey, SV Thakkar, HS Samra, HA Sathish, ...
Journal of pharmaceutical sciences 102 (7), 2136-2151, 2013
1022013
Mapping unstructured regions and synergistic folding in intrinsically disordered proteins with amide H/D exchange mass spectrometry
TR Keppel, BA Howard, DD Weis
Biochemistry 50 (40), 8722-8732, 2011
912011
Charge-mediated Fab-Fc interactions in an IgG1 antibody induce reversible self-association, cluster formation, and elevated viscosity
J Arora, Y Hu, R Esfandiary, HA Sathish, SM Bishop, SB Joshi, ...
mAbs 8 (8), 1561-1574, 2016
872016
Mapping Residual Structure in Intrinsically Disordered Proteins at Residue Resolution Using Millisecond Hydrogen/Deuterium Exchange and Residue Averaging
TR Keppel, DD Weis
Journal of The American Society for Mass Spectrometry 26 (4), 547-554, 2015
842015
The reaction of nitrogen dioxide with sea salt aerosol
DD Weis, GE Ewing
The Journal of Physical Chemistry A 103 (25), 4865-4873, 1999
841999
Reliable identification of significant differences in differential hydrogen exchange-mass spectrometry measurements using a hybrid significance testing approach
TS Hageman, DD Weis
Analytical chemistry 91 (13), 8008-8016, 2019
812019
Hydrogen-deuterium exchange mass spectrometry as an emerging analytical tool for stabilization and formulation development of therapeutic monoclonal antibodies
R Majumdar, CR Middaugh, DD Weis, DB Volkin
Journal of pharmaceutical sciences 104 (2), 327-345, 2015
802015
Hydrogen–deuterium exchange mass spectrometry as an emerging analytical tool for stabilization and formulation development of therapeutic monoclonal antibodies
R Majumdar, CR Middaugh, DD Weis, DB Volkin
Journal of pharmaceutical sciences 104 (2), 327-345, 2015
802015
Hydrogen Exchange Mass Spectrometry of Proteins
DD Weis
John Wiley & Sons, 2015
79*2015
Minimizing carry-over in an online pepsin digestion system used for the H/D exchange mass spectrometric analysis of an IgG1 monoclonal antibody
R Majumdar, P Manikwar, JM Hickey, J Arora, CR Middaugh, DB Volkin, ...
Journal of the American Society for Mass Spectrometry 23 (12), 2140-2148, 2012
772012
Hydrogen exchange mass spectrometry reveals protein interfaces and distant dynamic coupling effects during the reversible self-association of an IgG1 monoclonal antibody
J Arora, JM Hickey, R Majumdar, R Esfandiary, SM Bishop, HS Samra, ...
mAbs 7 (3), 525-539, 2015
752015
Correlations between changes in conformational dynamics and physical stability in a mutant IgG1 mAb engineered for extended serum half-life
R Majumdar, R Esfandiary, SM Bishop, HS Samra, CR Middaugh, ...
mAbs 7 (1), 84-95, 2015
692015
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