| 5′–3′ exonucleases in phosphorothioate-based oligonucleotide-directed mutagenesis JR Sayers, W Schmidt, F Eckstein Nucleic Acids Research 16 (3), 791-802, 1988 | 512 | 1988 |
| The evolution of pathways for aromatic hydrocarbon oxidation inPseudomonas PA Williams, JR Sayers Biodegradation 5, 195-217, 1994 | 278 | 1994 |
| Schistosoma mansoni worms induce anergy of T cells via selective up-regulation of programmed death ligand 1 on macrophages P Smith, CM Walsh, NE Mangan, RE Fallon, JR Sayers, ANJ McKenzie, ... The Journal of Immunology 173 (2), 1240-1248, 2004 | 244 | 2004 |
| A helical arch allowing single-stranded DNA to thread through T5 5'-exonuclease TA Ceska, JR Sayers, G Stier, D Suck Nature 382 (6586), 90-93, 1996 | 235 | 1996 |
| Schistosoma mansoni secretes a chemokine binding protein with antiinflammatory activity P Smith, RE Fallon, NE Mangan, CM Walsh, M Saraiva, JR Sayers, ... The Journal of experimental medicine 202 (10), 1319-1325, 2005 | 204 | 2005 |
| Investigating the interaction between osteoprotegerin and receptor activator of NF-κB or tumor necrosis factor-related apoptosis-inducing ligand: evidence for a pivotal role … S Vitovski, JS Phillips, J Sayers, PI Croucher Journal of Biological Chemistry 282 (43), 31601-31609, 2007 | 152 | 2007 |
| Synthesis and antiviral properties of (E)-5-(2-bromovinyl)-2'-deoxycytidine-related compounds AS Jones, JR Sayers, RT Walker, E De Clercq Journal of medicinal chemistry 31 (1), 268-271, 1988 | 121 | 1988 |
| Strand specific cleavage of phosphorothioate-containing DNA by reaction with restriction endonucleases in the presence of ethidium bromide JR Sayers, W Schmidt, A Wendler, F Eckstein Nucleic acids research 16 (3), 803-814, 1988 | 107 | 1988 |
| Rapid high-efficiency site-directed mutagenesis by the phosphorothioate approach. JR Sayers, C Krekel, F Eckstein BioTechniques 13 (4), 592-596, 1992 | 93 | 1992 |
| Nontypeable Haemophilus influenzae in carriage and disease: a difference in IgA1 protease activity levels S Vitovski, KT Dunkin, AJ Howard, JR Sayers Jama 287 (13), 1699-1705, 2002 | 91 | 2002 |
| Structure-specific DNA cleavage by 5′ nucleases TA Ceska, JR Sayers Trends in biochemical sciences 23 (9), 331-336, 1998 | 79 | 1998 |
| Roles of divalent metal ions in flap endonuclease–substrate interactions M Feng, D Patel, JJ Dervan, T Ceska, D Suck, I Haq, JR Sayers Nature structural & molecular biology 11 (5), 450-456, 2004 | 76 | 2004 |
| Designer proteases GW Duff, JR Sayers, S Vitovski US Patent 6,383,775, 2002 | 75 | 2002 |
| Bacteriophage collagen MCM Smith, N Burns, JR Sayers, JA Sorrell, SR Casjens, RW Hendrix, ... Science 279 (5358), 1831-1831, 1998 | 73 | 1998 |
| Invasive isolates of Neisseria meningitidis possess enhanced immunoglobulin A1 protease activity compared to colonizing strains S VITOVSKI, RC READ, JONR SAYERS The FASEB journal 13 (2), 331-337, 1999 | 72 | 1999 |
| Properties of overexpressed phage T5 D15 exonuclease. Similarities with Escherichia coli DNA polymerase I 5 ‘-3 ‘exonuclease. JR Sayers, F Eckstein Journal of Biological Chemistry 265 (30), 18311-18317, 1990 | 70 | 1990 |
| A single-strand specific endonuclease activity copurifies with overexpressed T5 D15 exonuclease JR Sayers, F Eckstein Nucleic acids research 19 (15), 4127-4132, 1991 | 60 | 1991 |
| Dynamic evidence for metal ion catalysis in the reaction mediated by a flap endonuclease MR Tock, E Frary, JR Sayers, JA Grasby The EMBO journal, 2003 | 59 | 2003 |
| A ligand-receptor fusion of growth hormone forms a dimer and is a potent long-acting agonist IR Wilkinson, E Ferrandis, PJ Artymiuk, M Teillot, C Soulard, C Touvay, ... Nature medicine 13 (9), 1108-1113, 2007 | 57 | 2007 |
| The synthesis and antiviral properties of (E)-5-(2-bromovinyl)-2'-deoxyuridine-related compounds M Ashwell, AS Jones, A Kumar, JR Sayers, RT Walker, T Sakuma, ... Tetrahedron 43 (20), 4601-4608, 1987 | 56 | 1987 |
