| A molecular grammar governing the driving forces for phase separation of prion-like RNA binding proteins J Wang, JM Choi, AS Holehouse, HO Lee, X Zhang, M Jahnel, ... Cell 174 (3), 688-699. e16, 2018 | 1157 | 2018 |
| Sequence determinants of intracellular phase separation by complex coacervation of a disordered protein CW Pak, M Kosno, AS Holehouse, SB Padrick, A Mittal, R Ali, AA Yunus, ... Molecular Cell 63 (1), 72-85, 2016 | 565 | 2016 |
| Phase separation of a yeast prion protein promotes cellular fitness TM Franzmann, M Jahnel, A Pozniakovsky, J Mahamid, AS Holehouse, ... Science 359 (6371), eaao5654, 2018 | 530 | 2018 |
| Valence and patterning of aromatic residues determine the phase behavior of prion-like domains EW Martin*, AS Holehouse*, I Peran*, M Farag, JJ Incicco, A Bremer, ... Science 367 (6478), 694-699, 2020 | 481 | 2020 |
| RNA-induced conformational switching and clustering of G3BP drive stress granule assembly by condensation J Guillén-Boixet*, A Kopach*, AS Holehouse, S Wittmann, M Jahnel, ... Cell 181 (2), 346-361. e17, 2020 | 449 | 2020 |
| Intrinsically disordered linkers determine the interplay between phase separation and gelation in multivalent proteins TS Harmon, AS Holehouse, MK Rosen, RV Pappu elife 6, e30294, 2017 | 442 | 2017 |
| Physical principles underlying the complex biology of intracellular phase transitions JM Choi-✝, AS Holehouse-✝, RV Pappu-✝ Annual Review of Biophysics 49, 107-133, 2020 | 405 | 2020 |
| Phase behaviour of disordered proteins underlying low density and high permeability of liquid organelles MT Wei*, S Elbaum-Garfinkle*, AS Holehouse*, CCH Chen, M Feric, ... Nature Chemistry 9, 1118–1125, 2017 | 397 | 2017 |
| CIDER: resources to analyze sequence-ensemble relationships of intrinsically disordered proteins AS Holehouse, RK Das, JN Ahad, MOG Richardson, RV Pappu Biophysical journal 112 (1), 16-21, 2017 | 326* | 2017 |
| The SARS-CoV-2 nucleocapsid protein is dynamic, disordered, and phase separates with RNA J Cubuk, JJ Alston, J Jeremías Incicco, S Singh, MD Stuchell-Brereton, ... Nature Communications 12 (1), 1–17, 2021 | 324 | 2021 |
| Spontaneous driving forces give rise to protein− RNA condensates with coexisting phases and complex material properties S Boeynaems, AS Holehouse, V Weinhardt, D Kovacs, J Van Lindt, ... Proceedings of the National Academy of Sciences 116 (16), 7889-7898, 2019 | 299 | 2019 |
| Sequence determinants of the conformational properties of an intrinsically disordered protein prior to and upon multisite phosphorylation EW Martin*, AS Holehouse*, CR Grace, A Hughes, RV Pappu, T Mittag Journal of the American Chemical Society 138 (47), 15323-15335, 2016 | 197 | 2016 |
| Quantitative analysis of multilayer organization of proteins and RNA in nuclear speckles at super resolution J Fei, M Jadaliha, TS Harmon, ITS Li, B Hua, Q Hao, AS Holehouse, ... Journal of cell science 130 (24), 4180-4192, 2017 | 194 | 2017 |
| Functional implications of intracellular phase transitions AS Holehouse, RV Pappu Biochemistry 57 (17), 2415-2423, 2018 | 167 | 2018 |
| Nucleo-cytoplasmic partitioning of ARF proteins controls auxin responses in Arabidopsis thaliana SK Powers, AS Holehouse, DA Korasick, KH Schreiber, NM Clark, H Jing, ... Molecular cell 76 (1), 177-190. e5, 2019 | 133 | 2019 |
| Phase Separation of Intrinsically Disordered Proteins AE Posey*, AS Holehouse*, RV Pappu Methods in Enzymology, 2018 | 132 | 2018 |
| SARS-CoV-2 requires cholesterol for viral entry and pathological syncytia formation DW Sanders, CC Jumper, PJ Ackerman, D Bracha, A Donlic, H Kim, ... Elife 10, e65962, 2021 | 131 | 2021 |
| Intrinsically disordered protein regions and phase separation: sequence determinants of assembly or lack thereof EW Martin, AS Holehouse Emerging topics in life sciences 4 (3), 307-329, 2020 | 114 | 2020 |
| A high-throughput mutational scan of an intrinsically disordered acidic transcriptional activation domain MV Staller, AS Holehouse, D Swain-Lenz, RK Das, RV Pappu, BA Cohen Cell Systems 6 (4), 444-455. e6, 2018 | 109 | 2018 |
| Collapse Transitions of Proteins and the Interplay Among Backbone, Sidechain, and Solvent Interactions AS Holehouse, RV Pappu Annual review of Biophysics, 2018 | 95 | 2018 |
Rohit V. PappuGene K. Beare Distinguished Professor of Biomedical Engineering, Washington University in St. LouisVerified email at wustl.edu
