| Innovative development and validation of an HPLC/DAD method for the qualitative and quantitative determination of major cannabinoids in cannabis plant material B De Backer, B Debrus, P Lebrun, L Theunis, N Dubois, L Decock, ... Journal of Chromatography B 877 (32), 4115-4124, 2009 | 301 | 2009 |
| Design spaces for analytical methods E Rozet, P Lebrun, P Hubert, B Debrus, B Boulanger TrAC Trends in Analytical Chemistry 42, 157-167, 2013 | 235 | 2013 |
| Design space approach in the optimization of the spray-drying process P Lebrun, F Krier, J Mantanus, H Grohganz, M Yang, E Rozet, ... European Journal of Pharmaceutics and Biopharmaceutics 80 (1), 226-234, 2012 | 163 | 2012 |
| Moisture content determination of pharmaceutical pellets by near infrared spectroscopy: method development and validation J Mantanus, E Ziémons, P Lebrun, E Rozet, R Klinkenberg, B Streel, ... Analytica chimica acta 642 (1), 186-192, 2009 | 113 | 2009 |
| Development of a new predictive modelling technique to find with confidence equivalence zone and design space of chromatographic analytical methods P Lebrun, B Govaerts, B Debrus, A Ceccato, G Caliaro, P Hubert, ... Chemometrics and Intelligent Laboratory Systems 91 (1), 4-16, 2008 | 112 | 2008 |
| Innovative high-performance liquid chromatography method development for the screening of 19 antimalarial drugs based on a generic approach, using design of experiments … B Debrus, P Lebrun, JM Kindenge, F Lecomte, A Ceccato, G Caliaro, ... Journal of Chromatography A 1218 (31), 5205-5215, 2011 | 106 | 2011 |
| ‘Quality by Design’approach for the analysis of impurities in pharmaceutical drug products and drug substances A Dispas, HT Avohou, P Lebrun, P Hubert, C Hubert TrAC Trends in Analytical Chemistry 101, 24-33, 2018 | 93 | 2018 |
| Application of new methodologies based on design of experiments, independent component analysis and design space for robust optimization in liquid chromatography B Debrus, P Lebrun, A Ceccato, G Caliaro, E Rozet, I Nistor, R Oprean, ... Analytica chimica acta 691 (1-2), 33-42, 2011 | 90 | 2011 |
| Acetaminophen determination in low-dose pharmaceutical syrup by NIR spectroscopy E Ziémons, J Mantanus, P Lebrun, E Rozet, B Evrard, P Hubert Journal of pharmaceutical and biomedical analysis 53 (3), 510-516, 2010 | 87 | 2010 |
| Improvement of a stability-indicating method by Quality-by-Design versus Quality-by-Testing: A case of a learning process C Hubert, P Lebrun, S Houari, E Ziemons, E Rozet, P Hubert Journal of pharmaceutical and biomedical analysis 88, 401-409, 2014 | 79 | 2014 |
| Active content determination of non-coated pharmaceutical pellets by near infrared spectroscopy: Method development, validation and reliability evaluation J Mantanus, E Ziemons, P Lebrun, E Rozet, R Klinkenberg, B Streel, ... Talanta 80 (5), 1750-1757, 2010 | 72 | 2010 |
| Continuous production of itraconazole-based solid dispersions by hot melt extrusion: preformulation, optimization and design space determination J Thiry, P Lebrun, C Vinassa, M Adam, L Netchacovitch, E Ziemons, ... International journal of pharmaceutics 515 (1-2), 114-124, 2016 | 63 | 2016 |
| Towards a full integration of optimization and validation phases: An analytical-quality-by-design approach C Hubert, S Houari, E Rozet, P Lebrun, P Hubert Journal of Chromatography A 1395, 88-98, 2015 | 59 | 2015 |
| A new criterion to assess distributional homogeneity in hyperspectral images of solid pharmaceutical dosage forms PY Sacré, P Lebrun, PF Chavez, CD Bleye, L Netchacovitch, E Rozet, ... Analytica chimica acta 818, 7-14, 2014 | 55 | 2014 |
| Quantitative determination of salbutamol sulfate impurities using achiral supercritical fluid chromatography A Dispas, V Desfontaine, B Andri, P Lebrun, D Kotoni, A Clarke, ... Journal of Pharmaceutical and Biomedical Analysis 134, 170-180, 2017 | 54 | 2017 |
| Evaluation of the quantitative performances of supercritical fluid chromatography: from method development to validation A Dispas, P Lebrun, E Ziemons, R Marini, E Rozet, P Hubert Journal of Chromatography A 1353, 78-88, 2014 | 50 | 2014 |
| Optimization of a PGSS process for a fenofibrate lipid-based solid dispersion formulation A Pestieau, F Krier, P Lebrun, B Evrard 18th Forum of Pharmaceutical Sciences, 2015 | 49* | 2015 |
| Optimization of a PGSS (particles from gas saturated solutions) process for a fenofibrate lipid-based solid dispersion formulation A Pestieau, F Krier, P Lebrun, A Brouwers, B Streel, B Evrard International journal of pharmaceutics 485 (1-2), 295-305, 2015 | 49 | 2015 |
| Robust method optimization strategy—A useful tool for method transfer: The case of SFC A Dispas, P Lebrun, B Andri, E Rozet, P Hubert Journal of pharmaceutical and biomedical analysis 88, 519-524, 2014 | 47 | 2014 |
| Application of an innovative design space optimization strategy to the development of liquid chromatographic methods to combat potentially counterfeit nonsteroidal anti … JK Mbinze, P Lebrun, B Debrus, A Dispas, N Kalenda, JMT Mbay, ... Journal of Chromatography A 1263, 113-124, 2012 | 46 | 2012 |
Ph HUBERTProfesseur Chimie analytique pharmaceutique, Université de LiègeПотвърден имейл адрес: Uliege.be
