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Brian J. Cafferty
Brian J. Cafferty
Director, Beam Therapeutics
Verified email at beamtx.com - Homepage
Title
Cited by
Cited by
Year
The origin of RNA and “my grandfather’s axe”
NV Hud, BJ Cafferty, R Krishnamurthy, LD Williams
Chemistry & biology 20 (4), 466-474, 2013
2412013
The synthesis of cyclic poly (ethylene imine) and exact linear analogues: an evaluation of gene delivery comparing polymer architectures
MA Cortez, WT Godbey, Y Fang, ME Payne, BJ Cafferty, KA Kosakowska, ...
Journal of the american chemical society 137 (20), 6541-6549, 2015
2072015
Efficient self-assembly in water of long noncovalent polymers by nucleobase analogues
BJ Cafferty, I Gállego, MC Chen, KI Farley, R Eritja, NV Hud
Journal of the American Chemical Society 135 (7), 2447-2450, 2013
1852013
Darwin's warm little pond: a one‐pot reaction for prebiotic phosphorylation and the mobilization of phosphate from minerals in a urea‐based solvent
B Burcar, M Pasek, M Gull, BJ Cafferty, F Velasco, NV Hud, ...
Angewandte Chemie International Edition 55 (42), 13249-13253, 2016
1402016
Spontaneous formation and base pairing of plausible prebiotic nucleotides in water
BJ Cafferty, DM Fialho, J Khanam, R Krishnamurthy, NV Hud
Nature communications 7 (1), 11328, 2016
1312016
Spontaneous Prebiotic Formation of a β-Ribofuranoside That Self-Assembles with a Complementary Heterocycle
MC Chen, BJ Cafferty, I Mamajanov, I Gállego, J Khanam, ...
Journal of the American Chemical Society 136 (15), 5640–5646, 2014
982014
Abiotic synthesis of RNA in water: a common goal of prebiotic chemistry and bottom-up synthetic biology
BJ Cafferty, NV Hud
Current opinion in chemical biology 22, 146-157, 2014
942014
Storage of information using small organic molecules
BJ Cafferty, AS Ten, MJ Fink, S Morey, DJ Preston, M Mrksich, ...
ACS central science 5 (5), 911-916, 2019
892019
Spontaneous symmetry breaking in the formation of supramolecular polymers: implications for the origin of biological homochirality
SC Karunakaran, BJ Cafferty, A Weigert‐Muñoz, GB Schuster, NV Hud
Angewandte Chemie 131 (5), 1467-1471, 2019
682019
Was a Pyrimidine‐Pyrimidine Base Pair the Ancestor of Watson‐Crick Base Pairs? Insights from a Systematic Approach to the Origin of RNA
BJ Cafferty, NV Hud
Israel Journal of Chemistry 55 (8), 891-905, 2015
622015
Autocatalytic Cycles in a Copper-Catalyzed Azide–Alkyne Cycloaddition Reaction
SN Semenov, L Belding, BJ Cafferty, MPS Mousavi, AM Finogenova, ...
Journal of the American Chemical Society 140 (32), 10221-10232, 2018
552018
Robustness, entrainment, and hybridization in dissipative molecular networks, and the origin of life
BJ Cafferty, ASY Wong, SN Semenov, L Belding, S Gmur, WTS Huck, ...
Journal of the American Chemical Society 141 (20), 8289-8295, 2019
502019
Ultra-sensitive pH control of supramolecular polymers and hydrogels: p K a matching of biomimetic monomers
BJ Cafferty, RR Avirah, GB Schuster, NV Hud
Chemical Science 5 (12), 4681-4686, 2014
442014
Fabricating 3D structures by combining 2D printing and relaxation of strain
BJ Cafferty, VE Campbell, P Rothemund, DJ Preston, A Ainla, ...
Advanced Materials Technologies 4 (1), 1800299, 2019
432019
Improved CRISPR genome editing using small highly active and specific engineered RNA-guided nucleases
MJ Schmidt, A Gupta, C Bednarski, S Gehrig-Giannini, F Richter, C Pitzler, ...
Nature communications 12 (1), 4219, 2021
372021
Storing and reading information in mixtures of fluorescent molecules
AA Nagarkar, SE Root, MJ Fink, AS Ten, BJ Cafferty, DS Richardson, ...
ACS Central Science 7 (10), 1728-1735, 2021
362021
Formation of supramolecular assemblies and liquid crystals by purine nucleobases and cyanuric acid in water: Implications for the possible origins of RNA
C Li, BJ Cafferty, SC Karunakaran, GB Schuster, NV Hud
Physical Chemistry Chemical Physics 18 (30), 20091-20096, 2016
362016
Silicate-promoted phosphorylation of glycerol in non-aqueous solvents: a prebiotically plausible route to organophosphates
M Gull, BJ Cafferty, NV Hud, MA Pasek
Life 7 (3), 29, 2017
292017
Water-soluble supramolecular polymers of paired and stacked heterocycles: Assembly, structure, properties, and a possible path to pre-RNA
GB Schuster, BJ Cafferty, SC Karunakaran, NV Hud
Journal of the American Chemical Society 143 (25), 9279-9296, 2021
272021
Using a chitosan nanolayer as an efficient pH buffer to protect pH-sensitive supramolecular assemblies
DV Andreeva, A Kollath, N Brezhneva, DV Sviridov, BJ Cafferty, ...
Physical Chemistry Chemical Physics 19 (35), 23843-23848, 2017
192017
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