| Tracking cancer drugs in living cells by thermal profiling of the proteome MM Savitski, FBM Reinhard, H Franken, T Werner, MF Savitski, ... Science 346 (6205), 1255784, 2014 | 976 | 2014 |
| Thermal proteome profiling for unbiased identification of direct and indirect drug targets using multiplexed quantitative mass spectrometry H Franken, T Mathieson, D Childs, GMA Sweetman, T Werner, I Tögel, ... Nature protocols 10 (10), 1567-1593, 2015 | 541 | 2015 |
| Systematic analysis of protein turnover in primary cells T Mathieson, H Franken, J Kosinski, N Kurzawa, N Zinn, G Sweetman, ... Nature communications 9 (1), 689, 2018 | 314 | 2018 |
| Preanalytical aspects and sample quality assessment in metabolomics studies of human blood P Yin, A Peter, H Franken, X Zhao, SS Neukamm, L Rosenbaum, M Lucio, ... Clinical chemistry 59 (5), 833-845, 2013 | 302 | 2013 |
| Thermal proteome profiling monitors ligand interactions with cellular membrane proteins FBM Reinhard, D Eberhard, T Werner, H Franken, D Childs, C Doce, ... Nature methods 12 (12), 1129-1131, 2015 | 285 | 2015 |
| Multiplexed proteome dynamics profiling reveals mechanisms controlling protein homeostasis MM Savitski, N Zinn, M Faelth-Savitski, D Poeckel, S Gade, I Becher, ... Cell 173 (1), 260-274. e25, 2018 | 200 | 2018 |
| Circulating lysophosphatidylcholines are markers of a metabolically benign nonalcoholic fatty liver R Lehmann, H Franken, S Dammeier, L Rosenbaum, K Kantartzis, ... Diabetes care 36 (8), 2331-2338, 2013 | 127 | 2013 |
| Identifying drug targets in tissues and whole blood with thermal-shift profiling J Perrin, T Werner, N Kurzawa, A Rutkowska, DD Childs, M Kalxdorf, ... Nature Biotechnology 38 (3), 303-308, 2020 | 124 | 2020 |
| Automated label-free quantification of metabolites from liquid chromatography–mass spectrometry data E Kenar, H Franken, S Forcisi, K Wörmann, HU Häring, R Lehmann, ... Molecular & Cellular Proteomics 13 (1), 348-359, 2014 | 93 | 2014 |
| Nonparametric analysis of thermal proteome profiles reveals novel drug-binding proteins D Childs, K Bach, H Franken, S Anders, N Kurzawa, M Bantscheff, ... Molecular & Cellular Proteomics 18 (12), 2506-2515, 2019 | 92 | 2019 |
| Activation of the mitogen-activated protein kinase (MAPK) signalling pathway in the liver of mice is related to plasma glucose levels after acute exercise M Hoene, H Franken, L Fritsche, R Lehmann, AK Pohl, HU Häring, A Zell, ... Diabetologia 53, 1131-1141, 2010 | 50 | 2010 |
| A computational method for detection of ligand-binding proteins from dose range thermal proteome profiles N Kurzawa, I Becher, S Sridharan, H Franken, A Mateus, S Anders, ... Nature communications 11 (1), 5783, 2020 | 36 | 2020 |
| TPP: Analyze thermal proteome profiling (TPP) experiments D Childs, N Kurzawa, H Franken, C Doce, M Savitski, W Huber R package version 3 (0), 0, 2023 | 20 | 2023 |
| Wrapper-and ensemble-based feature subset selection methods for biomarker discovery in targeted metabolomics H Franken, R Lehmann, HU Häring, A Fritsche, N Stefan, A Zell Pattern Recognition in Bioinformatics: 6th IAPR International Conference …, 2011 | 9 | 2011 |
| Inferring disease-related metabolite dependencies with a Bayesian optimization algorithm H Franken, A Seitz, R Lehmann, HU Häring, N Stefan, A Zell Evolutionary Computation, Machine Learning and Data Mining in Bioinformatics …, 2012 | 6 | 2012 |
| Computational analysis of ligand dose range thermal proteome profiles N Kurzawa, I Becher, S Sridharan, H Franken, A Mateus, S Anders, ... bioRxiv, 2020.05. 08.083709, 2020 | 2 | 2020 |
| Proteome thermal stability reflects organ physiology and identifies drug-target engagement in vivo J Perrin, T Werner, N Kurzawa, DD Childs, M Kalxdorf, A Rutkowska, ... bioRxiv, 500306, 2018 | 2 | 2018 |
| Metabolomics in diabetes research K Wörmann, M Lucio, S Forcisi, SS Heinzmann, E Kenar, H Franken, ... Der Diabetologe 8, 42-48, 2012 | 1 | 2012 |
| A computational method for detection of ligand-binding proteins from dose range thermal proteome profiles (Nov, 10.1038/s41467-020-19529-8, 2020) N Kurzawa, I Becher, S Sridharan, H Franken, A Mateus, S Anders, ... NATURE COMMUNICATIONS 12 (1), 2021 | | 2021 |
| Author Correction: A computational method for detection of ligand-binding proteins from dose range thermal proteome profiles N Kurzawa, I Becher, S Sridharan, H Franken, A Mateus, S Anders, ... Nature Communications 12, 2021 | | 2021 |
Marcus BantscheffCellzome, a GSK companyПотвърден имейл адрес: gsk.com
