Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants AT Dinkova-Kostova, WD Holtzclaw, RN Cole, K Itoh, N Wakabayashi, ... Proceedings of the National Academy of Sciences 99 (18), 11908-11913, 2002 | 2295 | 2002 |
Pyruvate kinase M2 is a PHD3-stimulated coactivator for hypoxia-inducible factor 1 W Luo, H Hu, R Chang, J Zhong, M Knabel, R O'Meally, RN Cole, ... Cell 145 (5), 732-744, 2011 | 1543 | 2011 |
Sir2-dependent activation of acetyl-CoA synthetase by deacetylation of active lysine VJ Starai, I Celic, RN Cole, JD Boeke, JC Escalante-Semerena Science 298 (5602), 2390-2392, 2002 | 669 | 2002 |
RACK1 competes with HSP90 for binding to HIF-1α and is required for O2-independent and HSP90 inhibitor-induced degradation of HIF-1α YV Liu, JH Baek, H Zhang, R Diez, RN Cole, GL Semenza Molecular cell 25 (2), 207-217, 2007 | 626 | 2007 |
Phosphorylation of the FUS low‐complexity domain disrupts phase separation, aggregation, and toxicity Z Monahan, VH Ryan, AM Janke, KA Burke, SN Rhoads, GH Zerze, ... The EMBO journal 36 (20), 2951-2967, 2017 | 624 | 2017 |
Mapping sites of O-GlcNAc modification using affinity tags for serine and threonine post-translational modifications L Wells, K Vosseller, RN Cole, JM Cronshaw, MJ Matunis, GW Hart Molecular & Cellular Proteomics 1 (10), 791-804, 2002 | 531 | 2002 |
Induced pluripotent stem cells from patients with Huntington's disease show CAG-repeat-expansion-associated phenotypes Hd iPsc Consortium Cell stem cell 11 (2), 264-278, 2012 | 498 | 2012 |
The microtubule-associated protein tau is extensively modified with O-linked N-acetylglucosamine CS Arnold, GVW Johnson, RN Cole, DLY Dong, M Lee, GW Hart Journal of Biological Chemistry 271 (46), 28741-28744, 1996 | 458 | 1996 |
Detecting significant changes in protein abundance K Kammers, RN Cole, C Tiengwe, I Ruczinski EuPA open proteomics 7, 11-19, 2015 | 294 | 2015 |
Astrocyte-shed extracellular vesicles regulate the peripheral leukocyte response to inflammatory brain lesions AM Dickens, LB Tovar-y-Romo, SW Yoo, AL Trout, M Bae, M Kanmogne, ... Science signaling 10 (473), eaai7696, 2017 | 251 | 2017 |
Alternative O-glycosylation/O-phosphorylation of the murine estrogen receptor β X Cheng, RN Cole, J Zaia, GW Hart Biochemistry 39 (38), 11609-11620, 2000 | 251 | 2000 |
Cytosolic O‐glycosylation is abundant in nerve terminals RN Cole, GW Hart Journal of neurochemistry 79 (5), 1080-1089, 2001 | 239 | 2001 |
The coactivator of transcription CREB-binding protein interacts preferentially with the glycosylated form of Stat5 C Gewinner, G Hart, N Zachara, R Cole, C Beisenherz-Huss, B Groner Journal of Biological Chemistry 279 (5), 3563-3572, 2004 | 219 | 2004 |
A comprehensive map of the human urinary proteome A Marimuthu, RN O’Meally, R Chaerkady, Y Subbannayya, V Nanjappa, ... Journal of proteome research 10 (6), 2734-2743, 2011 | 218 | 2011 |
Low concentrations of metformin suppress glucose production in hepatocytes through AMP-activated protein kinase (AMPK)*♦ J Cao, S Meng, E Chang, K Beckwith-Fickas, L Xiong, RN Cole, ... Journal of Biological Chemistry 289 (30), 20435-20446, 2014 | 203 | 2014 |
Electrophilic tuning of the chemoprotective natural product sulforaphane YH Ahn, Y Hwang, H Liu, XJ Wang, Y Zhang, KK Stephenson, ... Proceedings of the National Academy of Sciences 107 (21), 9590-9595, 2010 | 203 | 2010 |
Proteomic analysis of Chinese hamster ovary cells D Baycin-Hizal, DL Tabb, R Chaerkady, L Chen, NE Lewis, H Nagarajan, ... Journal of proteome research 11 (11), 5265-5276, 2012 | 198 | 2012 |
The nonlesional skin surface distinguishes atopic dermatitis with food allergy as a unique endotype DYM Leung, A Calatroni, LS Zaramela, PK LeBeau, N Dyjack, K Brar, ... Science translational medicine 11 (480), eaav2685, 2019 | 197 | 2019 |
Identification and quantification of S-nitrosylation by cysteine reactive tandem mass tag switch assay CI Murray, H Uhrigshardt, RN O’Meally, RN Cole, JE Van Eyk Molecular & Cellular Proteomics 11 (2), 2012 | 192 | 2012 |
Calcineurin promotes hypoxia-inducible factor 1α expression by dephosphorylating RACK1 and blocking RACK1 dimerization YV Liu, ME Hubbi, F Pan, KR McDonald, M Mansharamani, RN Cole, ... Journal of Biological Chemistry 282 (51), 37064-37073, 2007 | 191 | 2007 |