| Multiple causal variants underlie genetic associations in humans NS Abell, MK DeGorter, MJ Gloudemans, E Greenwald, KS Smith, Z He, ... Science 375 (6586), 1247-1254, 2022 | 92 | 2022 |
| FUN-LDA: a latent dirichlet allocation model for predicting tissue-specific functional effects of noncoding variation: methods and applications D Backenroth, Z He, K Kiryluk, V Boeva, L Petukhova, E Khurana, ... The American Journal of Human Genetics 102 (5), 920-942, 2018 | 87* | 2018 |
| Molecular signatures underlying neurofibrillary tangle susceptibility in Alzheimer’s disease M Otero-Garcia, SU Mahajani, D Wakhloo, W Tang, YQ Xue, S Morabito, ... Neuron 110 (18), 2929-2948. e8, 2022 | 62 | 2022 |
| Unified sequence-based association tests allowing for multiple functional annotations and meta-analysis of noncoding variation in metabochip data Z He, B Xu, S Lee, I Ionita-Laza The American Journal of Human Genetics 101 (3), 340-352, 2017 | 49 | 2017 |
| Association of rare APOE missense variants V236E and R251G with risk of Alzheimer disease Y Le Guen, ME Belloy, B Grenier-Boley, I De Rojas, A Castillo-Morales, ... JAMA neurology 79 (7), 652-663, 2022 | 43 | 2022 |
| A semi-supervised approach for predicting cell-type specific functional consequences of non-coding variation using MPRAs Z He, L Liu, K Wang, I Ionita-Laza Nature communications 9 (1), 5199, 2018 | 42 | 2018 |
| Organ aging signatures in the plasma proteome track health and disease HSH Oh, J Rutledge, D Nachun, R Pálovics, O Abiose, P Moran-Losada, ... Nature 624 (7990), 164-172, 2023 | 35 | 2023 |
| A genome-wide scan statistic framework for whole-genome sequence data analysis Z He, B Xu, J Buxbaum, I Ionita-Laza Nature communications 10 (1), 3018, 2019 | 35 | 2019 |
| Identification of putative causal loci in whole-genome sequencing data via knockoff statistics Z He, L Liu, C Wang, Y Le Guen, J Lee, S Gogarten, F Lu, S Montgomery, ... Nature communications 12 (1), 3152, 2021 | 26 | 2021 |
| An evolutionarily acquired microRNA shapes development of mammalian cortical projections JL Diaz, VB Siththanandan, V Lu, N Gonzalez-Nava, L Pasquina, ... Proceedings of the National Academy of Sciences 117 (46), 29113-29122, 2020 | 22 | 2020 |
| Set-based tests for the gene–environment interaction in longitudinal studies Z He, M Zhang, S Lee, JA Smith, SLR Kardia, VD Roux, B Mukherjee Journal of the American Statistical Association 112 (519), 966-978, 2017 | 22 | 2017 |
| Set-based tests for genetic association in longitudinal studies Z He, M Zhang, S Lee, JA Smith, X Guo, W Palmas, SLR Kardia, ... Biometrics 71 (3), 606-615, 2015 | 22 | 2015 |
| Modeling and testing for joint association using a genetic random field model Z He, M Zhang, X Zhan, Q Lu Biometrics 70 (3), 471-479, 2014 | 21 | 2014 |
| A novel age-informed approach for genetic association analysis in Alzheimer’s disease Y Le Guen, ME Belloy, V Napolioni, SJ Eger, G Kennedy, R Tao, Z He, ... Alzheimer's Research & Therapy 13, 1-14, 2021 | 20 | 2021 |
| Multitrait GWAS to connect disease variants and biological mechanisms H Julienne, V Laville, ZR McCaw, Z He, V Guillemot, C Lasry, A Ziyatdinov, ... PLoS genetics 17 (8), e1009713, 2021 | 19 | 2021 |
| Genome-wide analysis of common and rare variants via multiple knockoffs at biobank scale, with an application to Alzheimer disease genetics Z He, Y Le Guen, L Liu, J Lee, S Ma, AC Yang, X Liu, J Rutledge, ... The American Journal of Human Genetics 108 (12), 2336-2353, 2021 | 18 | 2021 |
| A generalized genetic random field method for the genetic association analysis of sequencing data M Li, Z He, M Zhang, X Zhan, C Wei, RC Elston, Q Lu Genetic epidemiology 38 (3), 242-253, 2014 | 18 | 2014 |
| Association of African Ancestry–Specific APOE Missense Variant R145C With Risk of Alzheimer Disease Y Le Guen, AC Raulin, MW Logue, R Sherva, ME Belloy, SJ Eger, A Chen, ... JAMA 329 (7), 551-560, 2023 | 15 | 2023 |
| Treatment practices and outcomes in continuous spike and wave during slow wave sleep: a multicenter collaboration FM Baumer, NA McNamara, AL Fine, E Pestana-Knight, RA Shellhaas, ... The Journal of pediatrics 232, 220-228. e3, 2021 | 13 | 2021 |
| KL∗ VS heterozygosity reduces brain amyloid in asymptomatic at-risk APOE∗ 4 carriers ME Belloy, SJ Eger, Y Le Guen, V Napolioni, KD Deters, HS Yang, ... Neurobiology of aging 101, 123-129, 2021 | 13 | 2021 |
Iuliana Ionita-LazaProfessor of Biostatistics, Columbia UniversityVerified email at columbia.edu
