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Ursula Germann
Ursula Germann
OnKognos Scientific Consulting & Services
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Title
Cited by
Cited by
Year
Expression of the human multidrug resistance cDNA in insect cells generates a high activity drug-stimulated membrane ATPase.
B Sarkadi, EM Price, RC Boucher, UA Germann, GA Scarborough
Journal of Biological Chemistry 267 (7), 4854-4858, 1992
7951992
Fluorescent cellular indicators are extruded by the multidrug resistance protein.
L Homolya, Z Holló, UA Germann, I Pastan, MM Gottesman, B Sarkadi
Journal of Biological Chemistry 268 (29), 21493-21496, 1993
6251993
Genetic analysis of the multidrug transporter
MM Gottesman, CA Hrycyna, PV Schoenlein, UA Germann, I Pastan
Annual review of genetics 29 (1), 607-649, 1995
6191995
P-glycoprotein—a mediator of multidrug resistance in tumour cells
UA Germann
European Journal of Cancer 32 (6), 927-944, 1996
5721996
Extracellular signal-regulated kinase 2 is necessary for mesoderm differentiation
Y Yao, W Li, J Wu, UA Germann, MSS Su, K Kuida, DM Boucher
Proceedings of the National Academy of Sciences 100 (22), 12759-12764, 2003
4292003
(S)-1-((S)-2-{[1-(4-amino-3-chloro-phenyl)-methanoyl]-amino}-3, 3-dimethyl-butanoyl)-pyrrolidine-2-carboxylic acid ((2R, 3S)-2-ethoxy-5-oxo-tetrahydro-furan-3-yl)-amide (VX-765 …
W Wannamaker, R Davies, M Namchuk, J Pollard, P Ford, G Ku, C Decker, ...
Journal of Pharmacology and Experimental Therapeutics 321 (2), 509-516, 2007
2812007
Two different regions of phosphoglycoprotein are photoaffinity-labeled by azidopine
EP Bruggemann, UA Germann, MM Gottesman, I Pastan
Journal of Biological Chemistry 264 (26), 15483-15488, 1989
2451989
Characterization of two allelic forms of Neurospora crassa laccase. Amino-and carboxyl-terminal processing of a precursor.
UA Germann, G Müller, PE Hunziker, K Lerch
Journal of Biological Chemistry 263 (2), 885-896, 1988
2381988
A single amino acid substitution makes ERK2 susceptible to pyridinyl imidazole inhibitors of p38 MAP kinase
T Fox, JT Coll, X Xie, PJ Ford, UA Germann, MD Porter, S Pazhanisamy, ...
Protein Science 7 (11), 2249-2255, 1998
2371998
Discovery of a novel, first-in-class, orally bioavailable azaindole inhibitor (VX-787) of influenza PB2
MP Clark, MW Ledeboer, I Davies, RA Byrn, SM Jones, E Perola, A Tsai, ...
Journal of medicinal chemistry 57 (15), 6668-6678, 2014
2202014
Targeting the MAPK signaling pathway in cancer: promising preclinical activity with the novel selective ERK1/2 inhibitor BVD-523 (ulixertinib)
UA Germann, BF Furey, W Markland, RR Hoover, AM Aronov, JJ Roix, ...
Molecular cancer therapeutics 16 (11), 2351-2363, 2017
2162017
Characterization of Phosphorylation-defective Mutants of Human P-glycoprotein Expressed in Mammalian Cells (∗)
UA Germann, TC Chambers, SV Ambudkar, T Licht, CO Cardarelli, ...
Journal of Biological Chemistry 271 (3), 1708-1716, 1996
2151996
P-glycoproteins: mediators of multidrug resistance
UA Germann, I Pastan, MM Gottesman
Seminars in cell biology 4 (1), 63-76, 1993
1951993
Altered drug-stimulated ATPase activity in mutants of the human multidrug resistance protein (∗)
M Müller, É Bakos, E Welker, A Váradi, UA Germann, MM Gottesman, ...
Journal of Biological Chemistry 271 (4), 1877-1883, 1996
1901996
Cellular and biochemical characterization of VX-710 as a chemosensitizer: reversal of P-glycoprotein-mediated multidrug resistance: in vitro
UA Germann, D Shlyakhter, VS Mason, RE Zelle, JP Duffy, V Galullo, ...
Anti-cancer drugs 8 (2), 125-140, 1997
1881997
Structure-guided design of potent and selective pyrimidylpyrrole inhibitors of extracellular signal-regulated kinase (ERK) using conformational control
AM Aronov, Q Tang, G Martinez-Botella, GW Bemis, J Cao, G Chen, ...
Journal of medicinal chemistry 52 (20), 6362-6368, 2009
1842009
Chemosensitization and drug accumulation effects of VX-710, verapamil, cyclosporin A, MS-209 and GF120918 in multidrug resistant HL60/ADR cells expressing the multidrug …
UA Germann, PJ Ford, D Shlyakhter, VS Mason, MW Harding
Anti-cancer drugs 8 (2), 141-155, 1997
1811997
c-Jun N-terminal kinases mediate reactivation of Akt and cardiomyocyte survival after hypoxic injury in vitro and in vivo
Z Shao, K Bhattacharya, E Hsich, L Park, B Walters, U Germann, ...
Circulation research 98 (1), 111-118, 2006
1792006
Both ATP sites of human P-glycoprotein are essential but not symmetric
CA Hrycyna, M Ramachandra, UA Germann, PW Cheng, I Pastan, ...
Biochemistry 38 (42), 13887-13899, 1999
1791999
Expression of the human multidrug transporter in insect cells by a recombinant baculovirus
UA Germann, MC Willingham, I Pastan, MM Gottesman
Biochemistry 29 (9), 2295-2303, 1990
1591990
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