Alister Funnell
Alister Funnell
Altius Institute for Biomedical Sciences
Потвърден имейл адрес: altius.org - Начална страница
Transcription factors LRF and BCL11A independently repress expression of fetal hemoglobin
T Masuda, X Wang, M Maeda, MC Canver, F Sher, APW Funnell, C Fisher, ...
Science 351 (6270), 285-289, 2016
Natural regulatory mutations elevate the fetal globin gene via disruption of BCL11A or ZBTB7A binding
GE Martyn, B Wienert, L Yang, M Shah, LJ Norton, J Burdach, R Kurita, ...
Nature genetics 50 (4), 498-503, 2018
Targeted Disruption of the Basic Krüppel-Like Factor Gene (Klf3) Reveals a Role in Adipogenesis
N Sue, BHA Jack, SA Eaton, RCM Pearson, APW Funnell, J Turner, ...
Molecular and cellular biology 28 (12), 3967-3978, 2008
Holding tight: cell junctions and cancer spread
AJ Knights, APW Funnell, M Crossley, RCM Pearson
Trends in cancer research 8, 61, 2012
A Network of Krüppel-like Factors (Klfs): Klf8 is repressed by Klf3 and activated by Klf1 in vivo
SA Eaton, APW Funnell, N Sue, H Nicholas, RCM Pearson, M Crossley
Journal of Biological Chemistry 283 (40), 26937-26947, 2008
Positively selected enhancer elements endow osteosarcoma cells with metastatic competence
JJ Morrow, I Bayles, APW Funnell, TE Miller, A Saiakhova, MM Lizardo, ...
Nature medicine 24 (2), 176-185, 2018
Editing the genome to introduce a beneficial naturally occurring mutation associated with increased fetal globin
B Wienert, APW Funnell, LJ Norton, RCM Pearson, LE Wilkinson-White, ...
Nature communications 6 (1), 7085, 2015
Erythroid Kruppel-like factor directly activates the basic Kruppel-like factor gene in erythroid cells
APW Funnell, CA Maloney, LJ Thompson, J Keys, M Tallack, AC Perkins, ...
Molecular and cellular biology 27 (7), 2777-2790, 2007
Multi-species, multi-transcription factor binding highlights conserved control of tissue-specific biological pathways
B Ballester, A Medina-Rivera, D Schmidt, M Gonzàlez-Porta, M Carlucci, ...
Elife 3, e02626, 2014
Adipokines and insulin action: A sensitive issue
AJ Knights, APW Funnell, RCM Pearson, M Crossley, KS Bell-Anderson
Adipocyte 3 (2), 88-96, 2014
Wake-up sleepy gene: reactivating fetal globin for β-hemoglobinopathies
B Wienert, GE Martyn, APW Funnell, KGR Quinlan, M Crossley
Trends in Genetics 34 (12), 927-940, 2018
PU. 1 and haematopoietic cell fate: dosage matters
KS Mak, APW Funnell, R Pearson, M Crossley
International journal of cell biology 2011, 2011
The mammalian zinc finger transcription factor Krüppel‐like factor 3 (KLF3/BKLF)
RCM Pearson, APW Funnell, M Crossley
IUBMB life 63 (2), 86-93, 2011
2p15-p16.1 microdeletions encompassing and proximal to BCL11A are associated with elevated HbF in addition to neurologic impairment
APW Funnell, P Prontera, V Ottaviani, M Piccione, A Giambona, A Maggio, ...
Blood, The Journal of the American Society of Hematology 126 (1), 89-93, 2015
Homo-and heterodimerization in transcriptional regulation
APW Funnell, M Crossley
Protein Dimerization and Oligomerization in Biology, 105-121, 2012
KLF1 directly activates expression of the novel fetal globin repressor ZBTB7A/LRF in erythroid cells
LJ Norton, APW Funnell, J Burdach, B Wienert, R Kurita, Y Nakamura, ...
Blood advances 1 (11), 685-692, 2017
The CACCC-Binding Protein KLF3/BKLF Represses a Subset of KLF1/EKLF Target Genes and Is Required for Proper Erythroid Maturation In Vivo
APW Funnell, LJ Norton, KS Mak, J Burdach, CM Artuz, NA Twine, ...
Molecular and cellular biology 32 (16), 3281-3292, 2012
Loss of Krüppel-like factor 3 (KLF3/BKLF) leads to upregulation of the insulin-sensitizing factor adipolin (FAM132A/CTRP12/C1qdc2)
KS Bell-Anderson, AP Funnell, H Williams, H Mat Jusoh, T Scully, WF Lim, ...
Diabetes 62 (8), 2728-2737, 2013
Generation of mice deficient in both KLF3/BKLF and KLF8 reveals a genetic interaction and a role for these factors in embryonic globin gene silencing
APW Funnell, KS Mak, NA Twine, GJ Pelka, LJ Norton, T Radziewic, ...
Molecular and cellular biology 33 (15), 2976-2987, 2013
Impaired B cell development in the absence of Krüppel-like factor 3
TT Vu, D Gatto, V Turner, APW Funnell, KS Mak, LJ Norton, W Kaplan, ...
The Journal of Immunology 187 (10), 5032-5042, 2011
Системата не може да изпълни операцията сега. Опитайте отново по-късно.
Статии 1–20