Cancer stem cells: targeting the roots of cancer, seeds of metastasis, and sources of therapy resistance V Adorno-Cruz, G Kibria, X Liu, M Doherty, DJ Junk, D Guan, C Hubert, ... Cancer research 75 (6), 924-929, 2015 | 246 | 2015 |
Cancer stem cell-specific scavenger receptor CD36 drives glioblastoma progression JS Hale, B Otvos, M Sinyuk, AG Alvarado, M Hitomi, K Stoltz, Q Wu, ... Stem cells 32 (7), 1746-1758, 2014 | 235 | 2014 |
Cancer stem cell-secreted macrophage migration inhibitory factor stimulates myeloid derived suppressor cell function and facilitates glioblastoma immune evasion B Otvos, DJ Silver, EE Mulkearns-Hubert, AG Alvarado, SM Turaga, ... Stem cells 34 (8), 2026-2039, 2016 | 224 | 2016 |
Glioblastoma cancer stem cells evade innate immune suppression of self-renewal through reduced TLR4 expression AG Alvarado, PS Thiagarajan, EE Mulkearns-Hubert, DJ Silver, JS Hale, ... Cell stem cell 20 (4), 450-461. e4, 2017 | 174 | 2017 |
Global immune fingerprinting in glioblastoma patient peripheral blood reveals immune-suppression signatures associated with prognosis TJ Alban, AG Alvarado, MD Sorensen, D Bayik, J Volovetz, E Serbinowski, ... JCI insight 3 (21), 2018 | 172 | 2018 |
Conservation and divergence of vulnerability and responses to stressors between human and mouse astrocytes J Li, L Pan, WG Pembroke, JE Rexach, MI Godoy, MC Condro, ... Nature communications 12 (1), 3958, 2021 | 126 | 2021 |
Differential connexin function enhances self-renewal in glioblastoma M Hitomi, LP Deleyrolle, EE Mulkearns-Hubert, A Jarrar, M Li, M Sinyuk, ... Cell reports 11 (7), 1031-1042, 2015 | 118 | 2015 |
A tumor suppressor function for notch signaling in forebrain tumor subtypes C Giachino, JL Boulay, R Ivanek, A Alvarado, C Tostado, S Lugert, ... Cancer cell 28 (6), 730-742, 2015 | 108 | 2015 |
Metronomic capecitabine as an immune modulator in glioblastoma patients reduces myeloid-derived suppressor cells DM Peereboom, TJ Alban, MM Grabowski, AG Alvarado, B Otvos, D Bayik, ... JCI insight 4 (22), 2019 | 92 | 2019 |
High-throughput flow cytometry screening reveals a role for junctional adhesion molecule a as a cancer stem cell maintenance factor JD Lathia, M Li, M Sinyuk, AG Alvarado, WA Flavahan, K Stoltz, ... Cell reports 6 (1), 117-129, 2014 | 88 | 2014 |
Development of a fluorescent reporter system to delineate cancer stem cells in triple-negative breast cancer PS Thiagarajan, M Hitomi, JS Hale, AG Alvarado, B Otvos, M Sinyuk, ... Stem cells 33 (7), 2114-2125, 2015 | 82 | 2015 |
Cx26 drives self-renewal in triple-negative breast cancer via interaction with NANOG and focal adhesion kinase PS Thiagarajan, M Sinyuk, SM Turaga, EE Mulkearns-Hubert, JS Hale, ... Nature communications 9 (1), 578, 2018 | 72 | 2018 |
Coordination of self-renewal in glioblastoma by integration of adhesion and microRNA signaling AG Alvarado, SM Turaga, P Sathyan, EE Mulkearns-Hubert, B Otvos, ... Neuro-oncology 18 (5), 656-666, 2016 | 40 | 2016 |
Discovery of a dual inhibitor of NQO1 and GSTP1 for treating glioblastoma K Lei, X Gu, AG Alvarado, Y Du, S Luo, EH Ahn, SS Kang, B Ji, X Liu, ... Journal of hematology & oncology 13, 1-21, 2020 | 38 | 2020 |
Taking a toll on self-renewal: TLR-mediated innate immune signaling in stem cells AG Alvarado, JD Lathia Trends in Neurosciences 39 (7), 463-471, 2016 | 26 | 2016 |
A molecular cascade modulates MAP1B and confers resistance to mTOR inhibition in human glioblastoma DR Laks, JA Oses-Prieto, AG Alvarado, J Nakashima, S Chand, ... Neuro-oncology 20 (6), 764-775, 2018 | 24 | 2018 |
A 4-miRNA signature to predict survival in glioblastomas SK Hermansen, MD Sørensen, A Hansen, S Knudsen, AG Alvarado, ... PloS one 12 (11), e0188090, 2017 | 23 | 2017 |
Cx25 contributes to leukemia cell communication and chemosensitivity M Sinyuk, AG Alvarado, P Nesmiyanov, J Shaw, EE Mulkearns-Hubert, ... Oncotarget 6 (31), 31508, 2015 | 21 | 2015 |
P300 promotes tumor recurrence by regulating radiation-induced conversion of glioma stem cells to vascular-like cells SD Muthukrishnan, R Kawaguchi, P Nair, R Prasad, Y Qin, M Johnson, ... Nature communications 13 (1), 6202, 2022 | 16 | 2022 |
Building bonds: cancer stem cells depend on their progeny to drive tumor progression SD Muthukrishnan, AG Alvarado, HI Kornblum Cell stem cell 22 (4), 473-474, 2018 | 5 | 2018 |