Следене
Leila Dorling
Leila Dorling
Centre for Cancer Genetic Epidemiology, University of Cambridge
Потвърден имейл адрес: medschl.cam.ac.uk
Заглавие
Позовавания
Позовавания
Година
Breast cancer risk genes—association analysis in more than 113,000 women
Breast Cancer Association Consortium
New England Journal of Medicine 384 (5), 428-439, 2021
6192021
Cancer Risks Associated With Germline PALB2 Pathogenic Variants: An International Study of 524 Families
X Yang, G Leslie, A Doroszuk, S Schneider, J Allen, B Decker, ...
Journal of clinical oncology 38 (7), 674-685, 2020
3512020
Randomized controlled trial of intensity-modulated radiotherapy for early breast cancer: 5-year results confirm superior overall cosmesis
MB Mukesh, GC Barnett, JS Wilkinson, AM Moody, C Wilson, L Dorling, ...
Journal of clinical oncology 31 (36), 4488-4495, 2013
2482013
A genome wide association study (GWAS) providing evidence of an association between common genetic variants and late radiotherapy toxicity
GC Barnett, D Thompson, L Fachal, S Kerns, C Talbot, RM Elliott, ...
Radiotherapy and Oncology 111 (2), 178-185, 2014
1772014
A three-stage genome-wide association study identifies a susceptibility locus for late radiotherapy toxicity at 2q24. 1
L Fachal, A Gomez-Caamano, GC Barnett, P Peleteiro, AM Carballo, ...
Nature genetics 46 (8), 891-894, 2014
1652014
Individual patient data meta-analysis shows a significant association between the ATM rs1801516 SNP and toxicity after radiotherapy in 5456 breast and prostate cancer patients
CN Andreassen, BS Rosenstein, SL Kerns, H Ostrer, D De Ruysscher, ...
Radiotherapy and Oncology 121 (3), 431-439, 2016
1262016
Replication of genetic polymorphisms reported to be associated with taxane-related sensory neuropathy in patients with early breast cancer treated with Paclitaxel
JE Abraham, Q Guo, L Dorling, J Tyrer, S Ingle, R Hardy, AL Vallier, ...
Clinical Cancer Research 20 (9), 2466-2475, 2014
1162014
Meta-analysis of genome wide association studies identifies genetic markers of late toxicity following radiotherapy for prostate cancer
SL Kerns, L Dorling, L Fachal, S Bentzen, PDP Pharoah, DR Barnes, ...
EBioMedicine 10, 150-163, 2016
912016
Radiogenomics consortium genome-wide association study meta-analysis of late toxicity after prostate cancer radiotherapy
SL Kerns, L Fachal, L Dorling, GC Barnett, A Baran, DR Peterson, ...
JNCI: Journal of the National Cancer Institute 112 (2), 179-190, 2020
882020
Pathology of tumors associated with pathogenic germline variants in 9 breast cancer susceptibility genes
N Mavaddat, L Dorling, S Carvalho, J Allen, A Gonzalez-Neira, R Keeman, ...
JAMA oncology 8 (3), e216744-e216744, 2022
602022
Prevalence of BRCA1 and BRCA2 pathogenic variants in a large, unselected breast cancer cohort
J Li, WX Wen, M Eklund, A Kvist, M Eriksson, HN Christensen, ...
International journal of cancer 144 (5), 1195-1204, 2019
482019
Patient reported outcome measures (PROMs) following forward planned field-in field IMRT: results from the Cambridge Breast IMRT trial
MB Mukesh, W Qian, JS Wilkinson, L Dorling, GC Barnett, AM Moody, ...
Radiotherapy and Oncology 111 (2), 270-275, 2014
462014
Inherited mutations in BRCA1 and BRCA2 in an unselected multiethnic cohort of Asian patients with breast cancer and healthy controls from Malaysia
WX Wen, J Allen, KN Lai, S Mariapun, SN Hasan, PS Ng, DSC Lee, ...
Journal of medical genetics 55 (2), 97-103, 2018
422018
A nested cohort study of 6,248 early breast cancer patients treated in neoadjuvant and adjuvant chemotherapy trials investigating the prognostic value of chemotherapy-related …
JE Abraham, L Hiller, L Dorling, AL Vallier, J Dunn, S Bowden, S Ingle, ...
BMC medicine 13, 1-9, 2015
372015
Prospective validation of the BOADICEA multifactorial breast cancer risk prediction model in a large prospective cohort study
X Yang, M Eriksson, K Czene, A Lee, G Leslie, M Lush, J Wang, J Dennis, ...
Journal of medical genetics 59 (12), 1196-1205, 2022
362022
Differential burden of rare and common variants on tumor characteristics, survival, and mode of detection in breast cancer
J Li, E Ugalde-Morales, WX Wen, B Decker, M Eriksson, A Torstensson, ...
Cancer research 78 (21), 6329-6338, 2018
252018
Patients with a high polygenic risk of breast cancer do not have an increased risk of radiotherapy toxicity
L Dorling, GC Barnett, K Michailidou, CE Coles, NG Burnet, J Yarnold, ...
Clinical Cancer Research 22 (6), 1413-1420, 2016
242016
Breast cancer risks associated with missense variants in breast cancer susceptibility genes
L Dorling, S Carvalho, J Allen, MT Parsons, C Fortuno, A González-Neira, ...
Genome medicine 14 (1), 51, 2022
222022
Splicing predictions, minigene analyses, and ACMG‐AMP clinical classification of 42 germline PALB2 splice‐site variants
A Valenzuela‐Palomo, E Bueno‐Martínez, L Sanoguera‐Miralles, ...
The Journal of Pathology 256 (3), 321-334, 2022
202022
Common genetic variation associated with increased susceptibility to prostate cancer does not increase risk of radiotherapy toxicity
M Ahmed, L Dorling, S Kerns, L Fachal, R Elliott, M Partliament, ...
British Journal of Cancer 114 (10), 1165-1174, 2016
182016
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Статии 1–20