|QuPath: Open source software for digital pathology image analysis|
P Bankhead, MB Loughrey, JA Fernández, Y Dombrowski, DG McArt, ...
Scientific reports 7 (1), 1-7, 2017
|Digital pathology and image analysis in tissue biomarker research|
PW Hamilton, P Bankhead, Y Wang, R Hutchinson, D Kieran, DG McArt, ...
Methods 70 (1), 59-73, 2014
|Validation of next generation sequencing technologies in comparison to current diagnostic gold standards for BRAF, EGFR and KRAS mutational analysis|
CM McCourt, DG McArt, K Mills, MA Catherwood, P Maxwell, DJ Waugh, ...
PLoS One 8 (7), e69604, 2013
|Challenging the cancer molecular stratification dogma: intratumoral heterogeneity undermines consensus molecular subtypes and potential diagnostic value in colorectal cancer|
PD Dunne, DG McArt, CA Bradley, PG O'Reilly, HL Barrett, R Cummins, ...
Clinical Cancer Research 22 (16), 4095-4104, 2016
|AXL is a key regulator of inherent and chemotherapy-induced invasion and predicts a poor clinical outcome in early-stage colon cancer|
PD Dunne, DG McArt, JK Blayney, M Kalimutho, S Greer, T Wang, ...
Clinical Cancer Research 20 (1), 164-175, 2014
|EphA2 expression is a key driver of migration and invasion and a poor prognostic marker in colorectal cancer|
PD Dunne, S Dasgupta, JK Blayney, DG McArt, KL Redmond, JA Weir, ...
Clinical Cancer Research 22 (1), 230-242, 2016
|Development and validation of a 28-gene hypoxia-related prognostic signature for localized prostate cancer|
L Yang, D Roberts, M Takhar, N Erho, BAS Bibby, N Thiruthaneeswaran, ...
EBioMedicine 31, 182-189, 2018
|Prognostic and therapeutic relevance of FLIP and procaspase-8 overexpression in non-small cell lung cancer|
JS Riley, R Hutchinson, DG McArt, N Crawford, C Holohan, I Paul, ...
Cell death & disease 4 (12), e951-e951, 2013
|The prognostic significance of the aberrant extremes of p53 immunophenotypes in breast cancer|
DP Boyle, DG McArt, G Irwin, CS Wilhelm‐Benartzi, TF Lioe, E Sebastian, ...
Histopathology 65 (3), 340-352, 2014
|Integrated tumor identification and automated scoring minimizes pathologist involvement and provides new insights to key biomarkers in breast cancer|
P Bankhead, JA Fernández, DG McArt, DP Boyle, G Li, MB Loughrey, ...
Laboratory investigation 98 (1), 15-26, 2018
|Cancer-cell intrinsic gene expression signatures overcome intratumoural heterogeneity bias in colorectal cancer patient classification|
PD Dunne, M Alderdice, PG O'Reilly, AC Roddy, AMB McCorry, ...
Nature communications 8 (1), 1-12, 2017
|Modelling the comet assay|
DG McArt, G McKerr, CV Howard, K Saetzler, GR Wasson
Biochemical Society Transactions 37 (4), 914-917, 2009
|Identification of candidate small-molecule therapeutics to cancer by gene-signature perturbation in connectivity mapping|
DG McArt, SD Zhang
PloS one 6 (1), e16382, 2011
|Transcriptional subtyping and CD8 immunohistochemistry identifies patients with stage II and III colorectal cancer with poor prognosis who benefit from adjuvant chemotherapy|
WL Allen, PD Dunne, S McDade, E Scanlon, M Loughrey, HG Coleman, ...
JCO precision oncology 2, 1-15, 2018
|Prospective patient stratification into robust cancer‐cell intrinsic subtypes from colorectal cancer biopsies|
M Alderdice, SD Richman, S Gollins, JP Stewart, C Hurt, R Adams, ...
The Journal of pathology 245 (1), 19-28, 2018
|Epidermal growth factor receptor immunohistochemistry: new opportunities in metastatic colorectal cancer|
RA Hutchinson, RA Adams, DG McArt, M Salto-Tellez, B Jasani, ...
Journal of translational medicine 13 (1), 1-11, 2015
|Automated tumor analysis for molecular profiling in lung cancer|
PW Hamilton, Y Wang, C Boyd, JA James, MB Loughrey, JP Hougton, ...
Oncotarget 6 (29), 27938, 2015
|Quantification of HER2 heterogeneity in breast cancer–implications for identification of sub-dominant clones for personalised treatment|
NE Buckley, C Forde, DG McArt, DP Boyle, PB Mullan, JA James, ...
Scientific reports 6 (1), 1-8, 2016
|Comprehensive molecular pathology analysis of small bowel adenocarcinoma reveals novel targets with potential for clinical utility|
MA Alvi, DG McArt, P Kelly, MA Fuchs, M Alderdice, CM McCabe, ...
Oncotarget 6 (25), 20863, 2015
|TBX2 represses CST6 resulting in uncontrolled legumain activity to sustain breast cancer proliferation: a novel cancer-selective target pathway with therapeutic opportunities.|
ZC D'Costa, C Higgins, CW Ong, GW Irwin, D Boyle, DG McArt, ...
Oncotarget 5 (6), 1609, 2014