Multi-step organic synthesis using solid-supported reagents and scavengers: a new paradigm in chemical library generation SV Ley, IR Baxendale, RN Bream, PS Jackson, AG Leach, ... Journal of the Chemical Society, Perkin Transactions 1, 3815-4195, 2000 | 958 | 2000 |
Enantioselective organocatalytic reductive amination RI Storer, DE Carrera, Y Ni, DWC MacMillan Journal of the American Chemical Society 128 (1), 84-86, 2006 | 853 | 2006 |
Squaramides: physical properties, synthesis and applications RI Storer, C Aciro, LH Jones Chemical Society Reviews 40 (5), 2330-2346, 2011 | 605 | 2011 |
Enantioselective Brønsted Acid-Catalyzed N-Acyliminium Cyclization Cascades ME Muratore, CA Holloway, AW Pilling, RI Storer, G Trevitt, DJ Dixon Journal of the American Chemical Society 131 (31), 10796-10797, 2009 | 437 | 2009 |
Ion channels as therapeutic targets: a drug discovery perspective SK Bagal, AD Brown, PJ Cox, K Omoto, RM Owen, DC Pryde, B Sidders, ... Journal of medicinal chemistry 56 (3), 593-624, 2013 | 318 | 2013 |
Physiology of hyperuricemia and urate-lowering treatments CL Benn, P Dua, R Gurrell, P Loudon, A Pike, RI Storer, C Vangjeli Frontiers in medicine 5, 160, 2018 | 281 | 2018 |
Put a ring on it: application of small aliphatic rings in medicinal chemistry MR Bauer, P Di Fruscia, SCC Lucas, IN Michaelides, JE Nelson, RI Storer, ... RSC Medicinal Chemistry 12 (4), 448-471, 2021 | 184 | 2021 |
Recent progress in sodium channel modulators for pain SK Bagal, ML Chapman, BE Marron, R Prime, RI Storer, NA Swain Bioorganic & medicinal chemistry letters 24 (16), 3690-3699, 2014 | 179 | 2014 |
Subtype-selective small molecule inhibitors reveal a fundamental role for Nav1. 7 in nociceptor electrogenesis, axonal conduction and presynaptic release AJ Alexandrou, AR Brown, ML Chapman, M Estacion, J Turner, MA Mis, ... PloS one 11 (4), e0152405, 2016 | 177 | 2016 |
A polymer-supported thionating reagent SV Ley, AG Leach, RI Storer Journal of the Chemical Society, Perkin Transactions 1, 358-361, 2001 | 158 | 2001 |
Voltage gated sodium channels as drug discovery targets SK Bagal, BE Marron, RM Owen, RI Storer, NA Swain Channels 9 (6), 360-366, 2015 | 139 | 2015 |
Multi‐step application of immobilized reagents and scavengers: a total synthesis of epothilone C RI Storer, T Takemoto, PS Jackson, DS Brown, IR Baxendale, SV Ley Chemistry–A European Journal 10 (10), 2529-2547, 2004 | 127 | 2004 |
Enantioselective organocatalytic aldehyde–aldehyde cross-aldol couplings. The broad utility of α-thioacetal aldehydes RI Storer, DWC MacMillan Tetrahedron 60 (35), 7705-7714, 2004 | 120 | 2004 |
A Total Synthesis of Epothilones Using Solid‐Supported Reagents and Scavengers RI Storer, T Takemoto, PS Jackson, SV Ley Angewandte Chemie International Edition 42 (22), 2521-2525, 2003 | 89 | 2003 |
Discovery of Clinical Candidate 4-[2-(5-Amino-1H-pyrazol-4-yl)-4-chlorophenoxy]-5-chloro-2-fluoro-N-1,3-thiazol-4-ylbenzenesulfonamide (PF-05089771): Design and … NA Swain, D Batchelor, S Beaudoin, BM Bechle, PA Bradley, AD Brown, ... Journal of Medicinal Chemistry 60 (16), 7029-7042, 2017 | 76 | 2017 |
Metabolism, pharmacokinetics and toxicity of functional groups: impact of chemical building blocks on ADMET DA Smith Royal Society of Chemistry, 2010 | 70 | 2010 |
Design and synthesis of a pan-Janus kinase inhibitor clinical candidate (PF-06263276) suitable for inhaled and topical delivery for the treatment of inflammatory diseases of … P Jones, RI Storer, YA Sabnis, FM Wakenhut, GA Whitlock, KS England, ... Journal of Medicinal Chemistry 60 (2), 767-786, 2017 | 52 | 2017 |
Sulfonamide derivatives S Beaudoin, MC Laufersweiler, CJ Markworth, BE Marron, DS Millan, ... US Patent 8,153,814, 2012 | 48 | 2012 |
GPCR structure, function, drug discovery and crystallography: report from academia-industry international conference (UK Royal Society) Chicheley Hall, 1–2 September 2014 A Heifetz, GFX Schertler, R Seifert, CG Tate, PM Sexton, VV Gurevich, ... Naunyn-Schmiedeberg's archives of pharmacology 388, 883-903, 2015 | 47 | 2015 |
Mild and Direct C–H Arylation of Quinoxalin-2 (1H)-ones with Aryldiazonium Salts under Metal-Free Conditions K Yin, R Zhang Synlett 29 (05), 597-602, 2018 | 44 | 2018 |