Adam Mead
Adam Mead
Потвърден имейл адрес: imm.ox.ac.uk - Начална страница
The impact of FLT3 internal tandem duplication mutant level, number, size, and interaction with NPM1 mutations in a large cohort of young adult patients with acute …
RE Gale, C Green, C Allen, AJ Mead, AK Burnett, RK Hills, DC Linch
Blood, The Journal of the American Society of Hematology 111 (5), 2776-2784, 2008
Coexistence of LMPP-like and GMP-like leukemia stem cells in acute myeloid leukemia
N Goardon, E Marchi, A Atzberger, L Quek, A Schuh, S Soneji, P Woll, ...
Cancer cell 19 (1), 138-152, 2011
Platelet-biased stem cells reside at the apex of the haematopoietic stem-cell hierarchy
A Sanjuan-Pla, IC Macaulay, CT Jensen, PS Woll, TC Luis, A Mead, ...
Nature 502 (7470), 232-236, 2013
FLT3 tyrosine kinase domain mutations are biologically distinct from and have a significantly more favorable prognosis than FLT3 internal tandem duplications in patients with …
AJ Mead, DC Linch, RK Hills, K Wheatley, AK Burnett, RE Gale
Blood, The Journal of the American Society of Hematology 110 (4), 1262-1270, 2007
Single-cell transcriptomics uncovers distinct molecular signatures of stem cells in chronic myeloid leukemia
A Giustacchini, S Thongjuea, N Barkas, PS Woll, BJ Povinelli, CAG Booth, ...
Nature medicine 23 (6), 692-702, 2017
Myelodysplastic syndromes are propagated by rare and distinct human cancer stem cells in vivo
PS Woll, U Kjällquist, O Chowdhury, H Doolittle, DC Wedge, S Thongjuea, ...
Cancer cell 25 (6), 794-808, 2014
Persistent malignant stem cells in del (5q) myelodysplasia in remission
R Tehranchi, PS Woll, K Anderson, N Buza-Vidas, T Mizukami, AJ Mead, ...
New England Journal of Medicine 363 (11), 1025-1037, 2010
Lymphomyeloid contribution of an immune-restricted progenitor emerging prior to definitive hematopoietic stem cells
C Böiers, J Carrelha, M Lutteropp, S Luc, JCA Green, E Azzoni, PS Woll, ...
Cell stem cell 13 (5), 535-548, 2013
Whole-genome sequencing of patients with rare diseases in a national health system
E Turro, WJ Astle, K Megy, S Gräf, D Greene, O Shamardina, HL Allen, ...
Nature 583 (7814), 96-102, 2020
Single-cell RNA sequencing reveals molecular and functional platelet bias of aged haematopoietic stem cells
A Grover, A Sanjuan-Pla, S Thongjuea, J Carrelha, A Giustacchini, ...
Nature communications 7 (1), 1-12, 2016
Distinct myeloid progenitor–differentiation pathways identified through single-cell RNA sequencing
R Drissen, N Buza-Vidas, P Woll, S Thongjuea, A Gambardella, ...
Nature immunology 17 (6), 666-676, 2016
Pacritinib versus best available therapy for the treatment of myelofibrosis irrespective of baseline cytopenias (PERSIST-1): an international, randomised, phase 3 trial
RA Mesa, AM Vannucchi, A Mead, M Egyed, A Szoke, A Suvorov, ...
The Lancet Haematology 4 (5), e225-e236, 2017
Genetic variation at MECOM, TERT, JAK2 and HBS1L-MYB predisposes to myeloproliferative neoplasms
W Tapper, AV Jones, R Kralovics, AS Harutyunyan, K Zoi, W Leung, ...
Nature communications 6 (1), 1-11, 2015
The earliest thymic T cell progenitors sustain B cell and myeloid lineage potential
S Luc, TC Luis, H Boukarabila, IC Macaulay, N Buza-Vidas, ...
Nature immunology 13 (4), 412-419, 2012
Perturbation of fetal liver hematopoietic stem and progenitor cell development by trisomy 21
A Roy, G Cowan, AJ Mead, S Filippi, G Bohn, A Chaidos, O Tunstall, ...
Proceedings of the National Academy of Sciences 109 (43), 17579-17584, 2012
Unravelling intratumoral heterogeneity through high-sensitivity single-cell mutational analysis and parallel RNA sequencing
A Rodriguez-Meira, G Buck, SA Clark, BJ Povinelli, V Alcolea, E Louka, ...
Molecular cell 73 (6), 1292-1305. e8, 2019
Erythropoietin guides multipotent hematopoietic progenitor cells toward an erythroid fate
A Grover, E Mancini, S Moore, AJ Mead, D Atkinson, KD Rasmussen, ...
Journal of Experimental Medicine 211 (2), 181-188, 2014
Germline selection shapes human mitochondrial DNA diversity
W Wei, S Tuna, MJ Keogh, KR Smith, TJ Aitman, PL Beales, DL Bennett, ...
Science 364 (6442), eaau6520, 2019
Ruxolitinib vs best available therapy for ET intolerant or resistant to hydroxycarbamide
CN Harrison, AJ Mead, A Panchal, S Fox, C Yap, E Gbandi, A Houlton, ...
Blood, The Journal of the American Society of Hematology 130 (17), 1889-1897, 2017
Genetically distinct leukemic stem cells in human CD34 acute myeloid leukemia are arrested at a hemopoietic precursor-like stage
L Quek, GW Otto, C Garnett, L Lhermitte, D Karamitros, B Stoilova, IJ Lau, ...
Journal of Experimental Medicine 213 (8), 1513-1535, 2016
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