| Radiation and dual checkpoint blockade activate non-redundant immune mechanisms in cancer C Twyman-Saint Victor, AJ Rech, A Maity, R Rengan, KE Pauken, ... Nature 520 (7547), 373-377, 2015 | 2295 | 2015 |
| The diverse functions of the PD1 inhibitory pathway AH Sharpe, KE Pauken Nature Reviews Immunology 18 (3), 153-167, 2018 | 1582 | 2018 |
| T-cell invigoration to tumour burden ratio associated with anti-PD-1 response AC Huang, MA Postow, RJ Orlowski, R Mick, B Bengsch, S Manne, W Xu, ... Nature 545 (7652), 60-65, 2017 | 1473 | 2017 |
| Overcoming T cell exhaustion in infection and cancer KE Pauken, EJ Wherry Trends in immunology 36 (4), 265-276, 2015 | 1104 | 2015 |
| Epigenetic stability of exhausted T cells limits durability of reinvigoration by PD-1 blockade KE Pauken, MA Sammons, PM Odorizzi, S Manne, J Godec, O Khan, ... Science 354 (6316), 1160-1165, 2016 | 1098 | 2016 |
| Tumor interferon signaling regulates a multigenic resistance program to immune checkpoint blockade JL Benci, B Xu, Y Qiu, TJ Wu, H Dada, C Twyman-Saint Victor, L Cucolo, ... Cell 167 (6), 1540-1554. e12, 2016 | 1017 | 2016 |
| Interactions between PD-1 and PD-L1 promote tolerance by blocking the TCR–induced stop signal BT Fife, KE Pauken, TN Eagar, T Obu, J Wu, Q Tang, M Azuma, ... Nature immunology 10 (11), 1185-1192, 2009 | 861 | 2009 |
| Bioenergetic insufficiencies due to metabolic alterations regulated by the inhibitory receptor PD-1 are an early driver of CD8+ T cell exhaustion B Bengsch, AL Johnson, M Kurachi, PM Odorizzi, KE Pauken, J Attanasio, ... immunity 45 (2), 358-373, 2016 | 701 | 2016 |
| Resident memory CD8 T cells trigger protective innate and adaptive immune responses JM Schenkel, KA Fraser, LK Beura, KE Pauken, V Vezys, D Masopust Science 346 (6205), 98-101, 2014 | 698 | 2014 |
| The role of the PD‐1 pathway in autoimmunity and peripheral tolerance BT Fife, KE Pauken Annals of the New York Academy of Sciences 1217 (1), 45-59, 2011 | 459 | 2011 |
| Genetic absence of PD-1 promotes accumulation of terminally differentiated exhausted CD8+ T cells PM Odorizzi, KE Pauken, MA Paley, A Sharpe, EJ Wherry Journal of Experimental Medicine 212 (7), 1125-1137, 2015 | 440 | 2015 |
| CD39 Expression Identifies Terminally Exhausted CD8+ T Cells PK Gupta, J Godec, D Wolski, E Adland, K Yates, KE Pauken, C Cosgrove, ... PLoS pathogens 11 (10), e1005177, 2015 | 381 | 2015 |
| CD4+ T cell anergy prevents autoimmunity and generates regulatory T cell precursors LA Kalekar, SE Schmiel, SL Nandiwada, WY Lam, LO Barsness, N Zhang, ... Nature immunology 17 (3), 304-314, 2016 | 247 | 2016 |
| Adverse events following cancer immunotherapy: obstacles and opportunities KE Pauken, M Dougan, NR Rose, AH Lichtman, AH Sharpe Trends in immunology 40 (6), 511-523, 2019 | 221 | 2019 |
| IL-15–independent maintenance of tissue-resident and boosted effector memory CD8 T cells JM Schenkel, KA Fraser, KA Casey, LK Beura, KE Pauken, V Vezys, ... The Journal of Immunology 196 (9), 3920-3926, 2016 | 174 | 2016 |
| Not-so-opposite ends of the spectrum: CD8+ T cell dysfunction across chronic infection, cancer and autoimmunity JL Collier, SA Weiss, KE Pauken, DR Sen, AH Sharpe Nature immunology 22 (7), 809-819, 2021 | 136 | 2021 |
| Conventional type I dendritic cells maintain a reservoir of proliferative tumor-antigen specific TCF-1+ CD8+ T cells in tumor-draining lymph nodes JM Schenkel, RH Herbst, D Canner, A Li, M Hillman, SL Shanahan, ... Immunity 54 (10), 2338-2353. e6, 2021 | 131 | 2021 |
| TIGIT and CD226: tipping the balance between costimulatory and coinhibitory molecules to augment the cancer immunotherapy toolkit KE Pauken, EJ Wherry Cancer cell 26 (6), 785-787, 2014 | 121 | 2014 |
| Interferon-gamma drives programmed death-ligand 1 expression on islet β cells to limit T cell function during autoimmune diabetes KC Osum, AL Burrack, T Martinov, NL Sahli, JS Mitchell, CG Tucker, ... Scientific reports 8 (1), 8295, 2018 | 117 | 2018 |
| SnapShot: T cell exhaustion KE Pauken, EJ Wherry Cell 163 (4), 1038-1038. e1, 2015 | 112 | 2015 |
