IFI16 and cGAS cooperate in the activation of STING during DNA sensing in human keratinocytes JF Almine, CAJ O’Hare, G Dunphy, IR Haga, RJ Naik, A Atrih, ... Nature communications 8 (1), 14392, 2017 | 314 | 2017 |
Two distinct types of E3 ligases work in unison to regulate substrate ubiquitylation DC Scott, DY Rhee, DM Duda, IR Kelsall, JL Olszewski, JA Paulo, ... Cell 166 (5), 1198-1214. e24, 2016 | 207 | 2016 |
The E3 ligase HOIL-1 catalyses ester bond formation between ubiquitin and components of the Myddosome in mammalian cells IR Kelsall, J Zhang, A Knebel, JSC Arthur, P Cohen Proceedings of the National Academy of Sciences 116 (27), 13293-13298, 2019 | 121 | 2019 |
Ppm1E is an in cellulo AMP-activated protein kinase phosphatase M Voss, J Paterson, IR Kelsall, C Martín-Granados, CJ Hastie, MW Peggie, ... Cellular signalling 23 (1), 114-124, 2011 | 112 | 2011 |
Roles of the TRAF6 and Pellino E3 ligases in MyD88 and RANKL signaling S Strickson, CH Emmerich, ETH Goh, J Zhang, IR Kelsall, T Macartney, ... Proceedings of the National Academy of Sciences 114 (17), E3481-E3489, 2017 | 109 | 2017 |
TRIAD1 and HHARI bind to and are activated by distinct neddylated Cullin‐RING ligase complexes IR Kelsall, DM Duda, JL Olszewski, K Hofmann, A Knebel, F Langevin, ... The EMBO journal 32 (21), 2848-2860, 2013 | 106 | 2013 |
Blocking an N-terminal acetylation–dependent protein interaction inhibits an E3 ligase DC Scott, JT Hammill, J Min, DY Rhee, M Connelly, VO Sviderskiy, ... Nature chemical biology 13 (8), 850-857, 2017 | 92 | 2017 |
Lys63/Met1-hybrid ubiquitin chains are commonly formed during the activation of innate immune signalling CH Emmerich, S Bakshi, IR Kelsall, J Ortiz-Guerrero, N Shpiro, P Cohen Biochemical and biophysical research communications 474 (3), 452-461, 2016 | 92 | 2016 |
HOIL‐1 ubiquitin ligase activity targets unbranched glucosaccharides and is required to prevent polyglucosan accumulation IR Kelsall, EH McCrory, Y Xu, CL Scudamore, SK Nanda, ... The EMBO Journal 41 (8), e109700, 2022 | 49 | 2022 |
Disruption of the allosteric phosphorylase a regulation of the hepatic glycogen-targeted protein phosphatase 1 improves glucose tolerance in vivo IR Kelsall, D Rosenzweig, PTW Cohen Cellular signalling 21 (7), 1123-1134, 2009 | 45 | 2009 |
The Fanconi anaemia components UBE2T and FANCM are functionally linked to nucleotide excision repair IR Kelsall, J Langenick, C MacKay, KJ Patel, AF Alpi PLoS One 7 (5), e36970, 2012 | 41 | 2012 |
The hepatic PP1 glycogen-targeting subunit interaction with phosphorylase a can be blocked by C-terminal tyrosine deletion or an indole drug IR Kelsall, S Munro, I Hallyburton, JL Treadway, PTW Cohen FEBS letters 581 (24), 4749-4753, 2007 | 36 | 2007 |
Non-lysine ubiquitylation: Doing things differently IR Kelsall Frontiers in Molecular Biosciences 9, 1008175, 2022 | 30 | 2022 |
R3F, a novel membrane‐associated glycogen targeting subunit of protein phosphatase 1 regulates glycogen synthase in astrocytoma cells in response to glucose and extracellular … IR Kelsall, M Voss, S Munro, DJR Cuthbertson, PTW Cohen Journal of neurochemistry 118 (4), 596-610, 2011 | 28 | 2011 |
Coupled monoubiquitylation of the co-E3 ligase DCNL1 by Ariadne-RBR E3 ubiquitin ligases promotes cullin-RING ligase complex remodeling IR Kelsall, YA Kristariyanto, A Knebel, NT Wood, Y Kulathu, AF Alpi Journal of Biological Chemistry 294 (8), 2651-5314, 2019 | 19 | 2019 |
HOIL-1, an atypical E3 ligase that controls MyD88 signalling by forming ester bonds between ubiquitin and components of the Myddosome P Cohen, IR Kelsall, SK Nanda, J Zhang Advances in Biological Regulation 75, 100666, 2020 | 16 | 2020 |
IFI16 and cGAS cooperate in the activation of STING during DNA sensing in human keratinocytes. Nat Commun 8: 14392 JF Almine, CA O’Hare, G Dunphy, IR Haga, RJ Naik, A Atrih, DJ Connolly, ... | 12 | 2017 |
Disruption of the striated muscle glycogen-targeting subunit of protein phosphatase 1: influence of the genetic background J Paterson, IR Kelsall, PTW Cohen Journal of molecular endocrinology 40 (2), 47-59, 2008 | 10 | 2008 |
HOIL-1-catalysed ubiquitylation of unbranched glucosaccharides and its activation by ubiquitin oligomers IR Kelsall, EH McCrory, Y Xu, CL Scudamore, SK Nanda, ... BioRxiv, 2021.09. 10.459791, 2021 | 6 | 2021 |
Erratum to “Ppm1E is an in cellulo AMP-activated protein kinase phosphatase”[Cell. Signalling 23 (2011) 114–124] M Voss, J Paterson, IR Kelsall, C Martín-Granados, CJ Hastie, MW Peggie, ... Cellular Signalling 5 (23), 947, 2011 | 1 | 2011 |