Interleukin-23 promotes a distinct CD4 T cell activation state characterized by the production of interleukin-17 S Aggarwal, N Ghilardi, MH Xie, FJ de Sauvage, AL Gurney Journal of Biological Chemistry 278 (3), 1910-1914, 2003 | 2584 | 2003 |
Interleukin-22 mediates early host defense against attaching and effacing bacterial pathogens Y Zheng, PA Valdez, DM Danilenko, Y Hu, SM Sa, Q Gong, AR Abbas, ... Nature medicine 14 (3), 282-289, 2008 | 2211 | 2008 |
Interleukin 27 limits autoimmune encephalomyelitis by suppressing the development of interleukin 17–producing T cells M Batten, J Li, S Yi, NM Kljavin, DM Danilenko, S Lucas, J Lee, ... Nature immunology 7 (9), 929-936, 2006 | 1078 | 2006 |
Defective STAT signaling by the leptin receptor in diabetic mice. N Ghilardi, S Ziegler, A Wiestner, R Stoffel, MH Heim, RC Skoda Proceedings of the National Academy of Sciences 93 (13), 6231-6235, 1996 | 1061 | 1996 |
Leptin receptor immunoreactivity in chemically defined target neurons of the hypothalamus ML Håkansson, H Brown, N Ghilardi, RC Skoda, B Meister Journal of Neuroscience 18 (1), 559-572, 1998 | 915 | 1998 |
Divergent roles of IL-23 and IL-12 in host defense against Klebsiella pneumoniae KI Happel, PJ Dubin, M Zheng, N Ghilardi, C Lockhart, LJ Quinton, ... The Journal of experimental medicine 202 (6), 761-769, 2005 | 832 | 2005 |
CRIg: a macrophage complement receptor required for phagocytosis of circulating pathogens KY Helmy, KJ Katschke, NN Gorgani, NM Kljavin, JM Elliott, L Diehl, ... Cell 124 (5), 915-927, 2006 | 701 | 2006 |
IL-27 regulates IL-12 responsiveness of naive CD4+ T cells through Stat1-dependent and-independent mechanisms S Lucas, N Ghilardi, J Li, FJ de Sauvage Proceedings of the National Academy of Sciences 100 (25), 15047-15052, 2003 | 648 | 2003 |
IL-23 compensates for the absence of IL-12p70 and is essential for the IL-17 response during tuberculosis but is dispensable for protection and antigen-specific IFN-γ responses … SA Khader, JE Pearl, K Sakamoto, L Gilmartin, GK Bell, DM Jelley-Gibbs, ... The Journal of Immunology 175 (2), 788-795, 2005 | 616 | 2005 |
Development of Th1-type immune responses requires the type I cytokine receptor TCCR QI Chen, N Ghilardi, H Wang, T Baker, MH Xie, A Gurney, IS Grewal, ... Nature 407 (6806), 916-920, 2000 | 505 | 2000 |
The leptin receptor activates janus kinase 2 and signals for proliferation in a factor-dependent cell line N Ghilardi, RC Skoda Molecular endocrinology 11 (4), 393-399, 1997 | 481 | 1997 |
Interleukin 12p40 is required for dendritic cell migration and T cell priming after Mycobacterium tuberculosis infection SA Khader, S Partida-Sanchez, G Bell, DM Jelley-Gibbs, S Swain, ... The Journal of experimental medicine 203 (7), 1805-1815, 2006 | 420 | 2006 |
A mouse knockout library for secreted and transmembrane proteins T Tang, L Li, J Tang, Y Li, WY Lin, F Martin, D Grant, M Solloway, L Parker, ... Nature biotechnology 28 (7), 749-755, 2010 | 392 | 2010 |
Interleukin (IL)-23 mediates Toxoplasma gondii–induced immunopathology in the gut via matrixmetalloproteinase-2 and IL-22 but independent of IL-17 M Muñoz, MM Heimesaat, K Danker, D Struck, U Lohmann, R Plickert, ... Journal of Experimental Medicine 206 (13), 3047-3059, 2009 | 325 | 2009 |
The role of IL-22 in intestinal health and disease ME Keir, T Yi, TT Lu, N Ghilardi Journal of Experimental Medicine 217 (3), 2020 | 281 | 2020 |
Compromised humoral and delayed-type hypersensitivity responses in IL-23-deficient mice N Ghilardi, N Kljavin, Q Chen, S Lucas, AL Gurney, FJ De Sauvage The Journal of Immunology 172 (5), 2827-2833, 2004 | 265 | 2004 |
Oral-resident natural Th17 cells and γδ T cells control opportunistic Candida albicans infections HR Conti, AC Peterson, L Brane, AR Huppler, N Hernández-Santos, ... Journal of Experimental Medicine 211 (10), 2075-2084, 2014 | 261 | 2014 |
Cutting edge: IL-27 is a potent inducer of IL-10 but not FoxP3 in murine T cells M Batten, NM Kljavin, J Li, MJ Walter, FJ de Sauvage, N Ghilardi The Journal of Immunology 180 (5), 2752-2756, 2008 | 259 | 2008 |
IL-27 supports germinal center function by enhancing IL-21 production and the function of T follicular helper cells M Batten, N Ramamoorthi, NM Kljavin, CS Ma, JH Cox, HS Dengler, ... Journal of Experimental Medicine 207 (13), 2895-2906, 2010 | 245 | 2010 |
Type I IFN induces IL-10 production in an IL-27–independent manner and blocks responsiveness to IFN-γ for production of IL-12 and bacterial killing in Mycobacterium … FW McNab, J Ewbank, A Howes, L Moreira-Teixeira, A Martirosyan, ... The Journal of Immunology 193 (7), 3600-3612, 2014 | 221 | 2014 |