| PRMT5 inhibition disrupts splicing and stemness in glioblastoma P Sachamitr, JC Ho, FE Ciamponi, W Ba-Alawi, FJ Coutinho, ... Nature communications 12 (1), 979, 2021 | 86 | 2021 |
| Hypoxia is a key driver of alternative splicing in human breast cancer cells J Han, J Li, JC Ho, GS Chia, H Kato, S Jha, H Yang, L Poellinger, KL Lee Scientific reports 7 (1), 4108, 2017 | 77 | 2017 |
| Dual inhibition of Src and GSK3 maintains mouse embryonic stem cells, whose differentiation is mechanically regulated by Src signaling T Shimizu, J Ueda, JC Ho, K Iwasaki, L Poellinger, I Harada, Y Sawada Stem cells 30 (7), 1394-1404, 2012 | 76 | 2012 |
| A molecular mechanism to switch the aryl hydrocarbon receptor from a transcription factor to an E3 ubiquitin ligase S Luecke-Johansson, M Gralla, H Rundqvist, JC Ho, RS Johnson, ... Molecular and cellular biology 37 (13), e00630-16, 2017 | 63 | 2017 |
| The hypoxia-inducible epigenetic regulators Jmjd1a and G9a provide a mechanistic link between angiogenesis and tumor growth J Ueda, JC Ho, KL Lee, S Kitajima, H Yang, W Sun, N Fukuhara, N Zaiden, ... Molecular and cellular biology 34 (19), 3702-3720, 2014 | 60 | 2014 |
| Structural insights into trans-histone regulation of H3K4 methylation by unique histone H4 binding of MLL3/4 Y Liu, S Qin, TY Chen, M Lei, SS Dhar, JC Ho, A Dong, P Loppnau, Y Li, ... Nature communications 10 (1), 36, 2019 | 35 | 2019 |
| Design and characterization of mutant and wildtype huntingtin proteins produced from a toolkit of scalable eukaryotic expression systems RJ Harding, P Loppnau, S Ackloo, A Lemak, A Hutchinson, B Hunt, ... Journal of Biological Chemistry 294 (17), 6986-7001, 2019 | 28 | 2019 |
| Inhibition of the H3K9 methyltransferase G9A attenuates oncogenicity and activates the hypoxia signaling pathway JC Ho, LN Abdullah, QY Pang, S Jha, EKH Chow, H Yang, H Kato, ... PLoS One 12 (11), e0188051, 2017 | 27 | 2017 |
| The impact of mechanical stress on stem cell properties: The link between cell shape and pluripotency JC Ho, J Ueda, T Shimizu Histol Histopathol 31 (1), 41-50, 2016 | 9 | 2016 |
| A KDM6 inhibitor potently induces ATF4 and its target gene expression through HRI activation and by UTX inhibition S Kitajima, W Sun, KL Lee, JC Ho, S Oyadomari, T Okamoto, H Masai, ... Scientific Reports 11 (1), 4538, 2021 | 4 | 2021 |
| Deletion breakpoint sequencing in patients with chromosomal rearrangements involving Xp22-p21 provides mechanistic insights ZH Zhang, JC Ho, BL Huang, LL McCabe, ERB McCabe Pediatric Research 53 (4), 257A-257A, 2003 | 1 | 2003 |
| PRMT5 is required for full-length HTT expression by repressing multiple proximal intronic polyadenylation sites M ALQAZZAZ, FE Ciamponi Sr, JC Ho, MI Maron, M Yadav, AM Sababi, ... bioRxiv, 2024.03. 14.584861, 2024 | | 2024 |
| PrePrint Journal Club Review: Small-molecule targeting of MUSASHI RNA-binding activity in acute myeloid leukemia D Dilworth, R Harding, K Hart, J Ho, D Ivanochko, G Luciani, M Mann, ... Authorea Preprints, 2018 | | 2018 |
| Molecular mechanisms in Xp22-p21 deletions among patients with complex glycerol kinase deficiency (GKD). YH Zhang, JC Ho, BL Huang, LL McCabe, KM Dipple, EB McCabe AMERICAN JOURNAL OF HUMAN GENETICS 73 (5), 319-319, 2003 | | 2003 |
| One year of ABHD2–Where are we now? A Ramsey, CUNCC Hill, C Arrowsmith, CMD Oxford, M Taylor, NG EBI, ... | | |
| A systematic review of drug-like ligands bound to helicases in the PDB A Ramsey, CUNCC Hill, C Arrowsmith, CMD Oxford, M Taylor, NG EBI, ... | | |
| A promising target for non-hormonal contraception–The α/β Hydrolase Domain 2 A Ramsey, CUNCC Hill, C Arrowsmith, CMD Oxford, M Taylor, NG EBI, ... | | |
| An Introduction to developing assays for HDACs A Ramsey, CUNCC Hill, C Arrowsmith, CMD Oxford, M Taylor, NG EBI, ... | | |
| Structure-Based PROTAC Design: Project Overview A Ramsey, CUNCC Hill, C Arrowsmith, CMD Oxford, M Taylor, NG EBI, ... | | |
| Interrogating PR/SET domains for the ability to bind SAH A Ramsey, CUNCC Hill, C Arrowsmith, CMD Oxford, M Taylor, NG EBI, ... | | |
