Dionicio Siegel
Dionicio Siegel
Потвърден имейл адрес: ucsd.edu - Начална страница
A convergent enantioselective route to structurally diverse 6-deoxytetracycline antibiotics
MG Charest, CD Lerner, JD Brubaker, DR Siegel, AG Myers
Science 308 (5720), 395-398, 2005
Global chemical effects of the microbiome include new bile-acid conjugations
RA Quinn, AV Melnik, A Vrbanac, T Fu, KA Patras, MP Christy, Z Bodai, ...
Nature 579 (7797), 123-129, 2020
Facile, novel methodology for the synthesis of spiro [pyrrolidin‐3, 3′‐oxindoles]: catalyzed ring expansion reactions of cyclopropanes by aldimines
PB Alper, C Meyers, A Lerchner, DR Siegel, EM Carreira
Angewandte Chemie International Edition 38 (21), 3186-3189, 1999
Mapping the malaria parasite druggable genome by using in vitro evolution and chemogenomics
AN Cowell, ES Istvan, AK Lukens, MG Gomez-Lorenzo, M Vanaerschot, ...
Science 359 (6372), 191-199, 2018
Caenorhabditis elegans selects distinct crawling and swimming gaits via dopamine and serotonin
A Vidal-Gadea, S Topper, L Young, A Crisp, L Kressin, E Elbel, T Maples, ...
Proceedings of the National Academy of Sciences 108 (42), 17504-17509, 2011
Metal-free oxidation of aromatic carbon–hydrogen bonds through a reverse-rebound mechanism
C Yuan, Y Liang, T Hernandez, A Berriochoa, KN Houk, D Siegel
Nature 499 (7457), 192-196, 2013
Synthesis of (+)-complanadine A, an inducer of neurotrophic factor excretion
C Yuan, CT Chang, A Axelrod, D Siegel
Journal of the American Chemical Society 132 (17), 5924-5925, 2010
Synthesis of (−)-tetracycline
MG Charest, DR Siegel, AG Myers
Journal of the American Chemical Society 127 (23), 8292-8293, 2005
Palmitic acid hydroxystearic acids activate GPR40, which is involved in their beneficial effects on glucose homeostasis
I Syed, J Lee, PM Moraes-Vieira, CJ Donaldson, A Sontheimer, P Aryal, ...
Cell metabolism 27 (2), 419-427. e4, 2018
Total synthesis of garsubellin A
DR Siegel, SJ Danishefsky
Journal of the American Chemical Society 128 (4), 1048-1049, 2006
A robust platform for the synthesis of new tetracycline antibiotics
C Sun, Q Wang, JD Brubaker, PM Wright, CD Lerner, K Noson, M Charest, ...
Journal of the American Chemical Society 130 (52), 17913-17927, 2008
Differentiation of nonconventional “carbanions”—the total synthesis of nemorosone and clusianone
C Tsukano, DR Siegel, SJ Danishefsky
Angewandte Chemie 119 (46), 8996-9000, 2007
Open-source discovery of chemical leads for next-generation chemoprotective antimalarials
Y Antonova-Koch, S Meister, M Abraham, MR Luth, S Ottilie, AK Lukens, ...
Science 362 (6419), eaat9446, 2018
Employing modular polyketide synthase ketoreductases as biocatalysts in the preparative chemoenzymatic syntheses of diketide chiral building blocks
SK Piasecki, CA Taylor, JF Detelich, J Liu, J Zheng, A Komsoukaniants, ...
Chemistry & biology 18 (10), 1331-1340, 2011
Synthesis of a broad array of highly functionalized, enantiomerically pure cyclohexanecarboxylic acid derivatives by microbial dihydroxylation of benzoic acid and subsequent …
AG Myers, DR Siegel, DJ Buzard, MG Charest
Organic Letters 3 (18), 2923-2926, 2001
Linoleic acid esters of hydroxy linoleic acids are anti-inflammatory lipids found in plants and mammals
MJ Kolar, S Konduri, T Chang, H Wang, C McNerlin, L Ohlsson, M Härröd, ...
Journal of Biological Chemistry 294 (27), 10698-10707, 2019
Semaphorin3a promotes advanced diabetic nephropathy
PK Aggarwal, D Veron, DB Thomas, D Siegel, G Moeckel, M Kashgarian, ...
Diabetes 64 (5), 1743-1759, 2015
PAHSAs enhance hepatic and systemic insulin sensitivity through direct and indirect mechanisms
P Zhou, A Santoro, OD Peroni, AT Nelson, A Saghatelian, D Siegel, ...
The Journal of clinical investigation 129 (10), 4138-4150, 2019
Gut bacteria responding to dietary change encode sialidases that exhibit preference for red meat-associated carbohydrates
LS Zaramela, C Martino, F Alisson-Silva, SD Rees, SL Diaz, L Chuzel, ...
Nature microbiology 4 (12), 2082-2089, 2019
Discovery of FAHFA-containing triacylglycerols and their metabolic regulation
D Tan, ME Ertunc, S Konduri, J Zhang, AM Pinto, Q Chu, BB Kahn, ...
Journal of the American Chemical Society 141 (22), 8798-8806, 2019
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