Directed differentiation of human pluripotent stem cells into intestinal tissue in vitro JR Spence, CN Mayhew, SA Rankin, MF Kuhar, JE Vallance, K Tolle, ... Nature 470 (7332), 105-109, 2011 | 2134 | 2011 |
Modelling human development and disease in pluripotent stem-cell-derived gastric organoids KW McCracken, EM Catá, CM Crawford, KL Sinagoga, M Schumacher, ... Nature 516 (7531), 400-404, 2014 | 1077 | 2014 |
In vitro generation of human pluripotent stem cell derived lung organoids BR Dye, DR Hill, MAH Ferguson, YH Tsai, MS Nagy, R Dyal, JM Wells, ... elife 4, e05098, 2015 | 845 | 2015 |
An in vivo model of human small intestine using pluripotent stem cells CL Watson, MM Mahe, J Múnera, JC Howell, N Sundaram, HM Poling, ... Nature medicine 20 (11), 1310-1314, 2014 | 610 | 2014 |
Modeling steatohepatitis in humans with pluripotent stem cell-derived organoids R Ouchi, S Togo, M Kimura, T Shinozawa, M Koido, H Koike, ... Cell metabolism 30 (2), 374-384. e6, 2019 | 467 | 2019 |
Regulation of heat shock transcription factor 1 by stress-induced SUMO-1 modification Y Hong, R Rogers, MJ Matunis, CN Mayhew, M Goodson, OK Park-Sarge, ... Journal of Biological Chemistry 276 (43), 40263-40267, 2001 | 345 | 2001 |
Mechanism of hsp70i gene bookmarking H Xing, DC Wilkerson, CN Mayhew, EJ Lubert, HS Skaggs, ML Goodson, ... Science 307 (5708), 421-423, 2005 | 212 | 2005 |
E2F1 uses the ATM signaling pathway to induce p53 and Chk2 phosphorylation and apoptosis JT Powers, SK Hong, CN Mayhew, PM Rogers, ES Knudsen, DG Johnson Molecular Cancer Research 2 (4), 203-214, 2004 | 204 | 2004 |
Paracrine signals regulate human liver organoid maturation from induced pluripotent stem cells A Asai, E Aihara, C Watson, R Mourya, T Mizuochi, P Shivakumar, ... Development 144 (6), 1056-1064, 2017 | 171 | 2017 |
Proliferative suppression by CDK4/6 inhibition: complex function of the retinoblastoma pathway in liver tissue and hepatoma cells DB Rivadeneira, CN Mayhew, C Thangavel, E Sotillo, CA Reed, X Graña, ... Gastroenterology 138 (5), 1920-1930. e2, 2010 | 152 | 2010 |
Integrated genomic analysis of diverse induced pluripotent stem cells from the progenitor cell biology consortium N Salomonis, PJ Dexheimer, L Omberg, R Schroll, S Bush, J Huo, ... Stem cell reports 7 (1), 110-125, 2016 | 131 | 2016 |
Liver-specific pRB loss results in ectopic cell cycle entry and aberrant ploidy CN Mayhew, EE Bosco, SR Fox, T Okaya, P Tarapore, SJ Schwemberger, ... Cancer research 65 (11), 4568-4577, 2005 | 128 | 2005 |
RB signaling prevents replication‐dependent DNA double‐strand breaks following genotoxic insult EE Bosco, CN Mayhew, RF Hennigan, J Sage, T Jacks, ES Knudsen Nucleic acids research 32 (1), 25-34, 2004 | 111 | 2004 |
RB loss abrogates cell cycle control and genome integrity to promote liver tumorigenesis CN Mayhew, SL Carter, SR Fox, CR Sexton, CA Reed, SV Srinivasan, ... Gastroenterology 133 (3), 976-984, 2007 | 101 | 2007 |
HSF1 modulation of Hsp70 mRNA polyadenylation via interaction with symplekin H Xing, CN Mayhew, KE Cullen, OK Park-Sarge, KD Sarge Journal of Biological Chemistry 279 (11), 10551-10555, 2004 | 91 | 2004 |
Converting human pluripotent stem cells into β-cells: recent advances and future challenges CN Mayhew, JM Wells Current opinion in organ transplantation 15 (1), 54-60, 2010 | 86 | 2010 |
Wnt11/5a complex formation caused by tyrosine sulfation increases canonical signaling activity SW Cha, E Tadjuidje, J White, J Wells, C Mayhew, C Wylie, J Heasman Current biology 19 (18), 1573-1580, 2009 | 86 | 2009 |
Loss of the retinoblastoma tumor suppressor: differential action on transcriptional programs related to cell cycle control and immune function MP Markey, J Bergseid, EE Bosco, K Stengel, H Xu, CN Mayhew, ... Oncogene 26 (43), 6307-6318, 2007 | 85 | 2007 |
Activated STAT5 confers resistance to intestinal injury by increasing intestinal stem cell proliferation and regeneration S Gilbert, H Nivarthi, CN Mayhew, YH Lo, TK Noah, J Vallance, T Rülicke, ... Stem cell reports 4 (2), 209-225, 2015 | 73 | 2015 |
Molecular, phenotypic, and sample-associated data to describe pluripotent stem cell lines and derivatives K Daily, SJ Ho Sui, LM Schriml, PJ Dexheimer, N Salomonis, R Schroll, ... Scientific data 4 (1), 1-10, 2017 | 69 | 2017 |