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Chris Mayhew
Chris Mayhew
Assistant Professor of Pediatrics, Director Pluripotent Stem Cell Facility
Verified email at cchmc.org - Homepage
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Cited by
Year
Directed differentiation of human pluripotent stem cells into intestinal tissue in vitro
JR Spence, CN Mayhew, SA Rankin, MF Kuhar, JE Vallance, K Tolle, ...
Nature 470 (7332), 105-109, 2011
20202011
Modelling human development and disease in pluripotent stem-cell-derived gastric organoids
KW McCracken, EM Catá, CM Crawford, KL Sinagoga, M Schumacher, ...
Nature 516 (7531), 400-404, 2014
10182014
In vitro generation of human pluripotent stem cell derived lung organoids
BR Dye, DR Hill, MAH Ferguson, YH Tsai, MS Nagy, R Dyal, JM Wells, ...
elife 4, e05098, 2015
7902015
An in vivo model of human small intestine using pluripotent stem cells
CL Watson, MM Mahe, J Múnera, JC Howell, N Sundaram, HM Poling, ...
Nature medicine 20 (11), 1310-1314, 2014
5702014
Modeling steatohepatitis in humans with pluripotent stem cell-derived organoids
R Ouchi, S Togo, M Kimura, T Shinozawa, M Koido, H Koike, ...
Cell metabolism 30 (2), 374-384. e6, 2019
4032019
Regulation of heat shock transcription factor 1 by stress-induced SUMO-1 modification
Y Hong, R Rogers, MJ Matunis, CN Mayhew, M Goodson, OK Park-Sarge, ...
Journal of Biological Chemistry 276 (43), 40263-40267, 2001
3422001
Mechanism of hsp70i gene bookmarking
H Xing, DC Wilkerson, CN Mayhew, EJ Lubert, HS Skaggs, ML Goodson, ...
Science 307 (5708), 421-423, 2005
2072005
E2F1 uses the ATM signaling pathway to induce p53 and Chk2 phosphorylation and apoptosis
JT Powers, SK Hong, CN Mayhew, PM Rogers, ES Knudsen, DG Johnson
Molecular Cancer Research 2 (4), 203-214, 2004
2012004
Paracrine signals regulate human liver organoid maturation from induced pluripotent stem cells
A Asai, E Aihara, C Watson, R Mourya, T Mizuochi, P Shivakumar, ...
Development 144 (6), 1056-1064, 2017
1632017
Proliferative suppression by CDK4/6 inhibition: complex function of the retinoblastoma pathway in liver tissue and hepatoma cells
DB Rivadeneira, CN Mayhew, C Thangavel, E Sotillo, CA Reed, X Graña, ...
Gastroenterology 138 (5), 1920-1930. e2, 2010
1482010
Integrated genomic analysis of diverse induced pluripotent stem cells from the progenitor cell biology consortium
N Salomonis, PJ Dexheimer, L Omberg, R Schroll, S Bush, J Huo, ...
Stem cell reports 7 (1), 110-125, 2016
1252016
Liver-specific pRB loss results in ectopic cell cycle entry and aberrant ploidy
CN Mayhew, EE Bosco, SR Fox, T Okaya, P Tarapore, SJ Schwemberger, ...
Cancer research 65 (11), 4568-4577, 2005
1252005
RB signaling prevents replication‐dependent DNA double‐strand breaks following genotoxic insult
EE Bosco, CN Mayhew, RF Hennigan, J Sage, T Jacks, ES Knudsen
Nucleic acids research 32 (1), 25-34, 2004
1102004
RB loss abrogates cell cycle control and genome integrity to promote liver tumorigenesis
CN Mayhew, SL Carter, SR Fox, CR Sexton, CA Reed, SV Srinivasan, ...
Gastroenterology 133 (3), 976-984, 2007
1012007
HSF1 modulation of Hsp70 mRNA polyadenylation via interaction with symplekin
H Xing, CN Mayhew, KE Cullen, OK Park-Sarge, KD Sarge
Journal of Biological Chemistry 279 (11), 10551-10555, 2004
912004
Wnt11/5a complex formation caused by tyrosine sulfation increases canonical signaling activity
SW Cha, E Tadjuidje, J White, J Wells, C Mayhew, C Wylie, J Heasman
Current biology 19 (18), 1573-1580, 2009
862009
Converting human pluripotent stem cells into β-cells: recent advances and future challenges
CN Mayhew, JM Wells
Current opinion in organ transplantation 15 (1), 54-60, 2010
842010
Loss of the retinoblastoma tumor suppressor: differential action on transcriptional programs related to cell cycle control and immune function
MP Markey, J Bergseid, EE Bosco, K Stengel, H Xu, CN Mayhew, ...
Oncogene 26 (43), 6307-6318, 2007
802007
Activated STAT5 confers resistance to intestinal injury by increasing intestinal stem cell proliferation and regeneration
S Gilbert, H Nivarthi, CN Mayhew, YH Lo, TK Noah, J Vallance, T Rülicke, ...
Stem cell reports 4 (2), 209-225, 2015
722015
Molecular, phenotypic, and sample-associated data to describe pluripotent stem cell lines and derivatives
K Daily, SJ Ho Sui, LM Schriml, PJ Dexheimer, N Salomonis, R Schroll, ...
Scientific data 4 (1), 1-10, 2017
672017
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