Aleksandr B. Sahakyan
Aleksandr B. Sahakyan
Group Leader and PI, Integrative Comp. Biology and Machine Learning, WIMM, RDM, University of Oxford
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rG4-seq reveals widespread formation of G-quadruplex structures in the human transcriptome
CK Kwok, G Marsico, AB Sahakyan, VS Chambers, S Balasubramanian
Nature methods 13 (10), 841-844, 2016
Whole genome experimental maps of DNA G-quadruplexes in multiple species
G Marsico, VS Chambers, AB Sahakyan, P McCauley, JM Boutell, ...
Nucleic acids research 47 (8), 3862-3874, 2019
Machine learning model for sequence-driven DNA G-quadruplex formation
AB Sahakyan, VS Chambers, G Marsico, T Santner, M Di Antonio, ...
Scientific reports 7 (1), 14535, 2017
Structural analysis using SHALiPE to reveal RNA G‐quadruplex formation in human precursor microRNA
CK Kwok, AB Sahakyan, S Balasubramanian
Angewandte Chemie 128 (31), 9104-9107, 2016
Cyclophilin A catalyzes proline isomerization by an electrostatic handle mechanism
C Camilloni, AB Sahakyan, MJ Holliday, NG Isern, F Zhang, ...
Proceedings of the National Academy of Sciences 111 (28), 10203-10208, 2014
Structure-based prediction of methyl chemical shifts in proteins
AB Sahakyan, WF Vranken, A Cavalli, M Vendruscolo
Journal of biomolecular NMR 50, 331-346, 2011
G-quadruplex structures within the 3′ UTR of LINE-1 elements stimulate retrotransposition
AB Sahakyan, P Murat, C Mayer, S Balasubramanian
Nature Structural and Molecular Biology 24, 2017
Selective chemical labeling of natural T modifications in DNA
RE Hardisty, F Kawasaki, AB Sahakyan, S Balasubramanian
Journal of The American Chemical Society 137 (29), 9270-9272, 2015
Structural analysis reveals the formation and role of RNA G-quadruplex structures in human mature microRNAs
KL Chan, B Peng, MI Umar, CY Chan, AB Sahakyan, MTN Le, CK Kwok
Chemical communications 54 (77), 10878-10881, 2018
ALMOST: an all atom molecular simulation toolkit for protein structure determination
B Fu, AB Sahakyan, C Camilloni, GG Tartaglia, E Paci, A Caflisch, ...
Journal of Computational Chemistry 35 (14), 1101-1105, 2014
Analysis of the contributions of ring current and electric field effects to the chemical shifts of RNA bases
AB Sahakyan, M Vendruscolo
The Journal of Physical Chemistry B 117 (7), 1989-1998, 2013
Long genes and genes with multiple splice variants are enriched in pathways linked to cancer and other multigenic diseases
AB Sahakyan, S Balasubramanian
BMC Genomics 17 (1), 225, 2016
Using Side‐Chain Aromatic Proton Chemical Shifts for a Quantitative Analysis of Protein Structures
AB Sahakyan, WF Vranken, A Cavalli, M Vendruscolo
Angewandte Chemie International Edition 50 (41), 9620-9623, 2011
Thermal and pH Stabilities of i‐DNA: Confronting in vitro Experiments with Models and In‐Cell NMR Data
M Cheng, D Qiu, L Tamon, E Ištvánková, P Víšková, S Amrane, A Guédin, ...
Angewandte Chemie International Edition 60 (18), 10286-10294, 2021
A conformational ensemble derived using NMR methyl chemical shifts reveals a mechanical clamping transition that gates the binding of the HU protein to DNA
A Kannan, C Camilloni, AB Sahakyan, A Cavalli, M Vendruscolo
Journal of the American Chemical Society 136 (6), 2204-2207, 2014
Dielectric permittivity and temperature effects on spin–spin couplings studied on acetonitrile
AB Sahakyan, AA Shahkhatuni, AG Shahkhatuni, HA Panosyan
Magnetic Resonance in Chemistry 46 (1), 63-68, 2008
Electric Field Effects on One-Bond Indirect Spin− Spin Coupling Constants and Possible Biomolecular Perspectives
AB Sahakyan, AG Shahkhatuni, AA Shahkhatuni, HA Panosyan
The Journal of Physical Chemistry A 112 (16), 3576-3586, 2008
A geometrical parametrization of C1′-C5′ RNA ribose chemical shifts calculated by density functional theory
R Suardíaz, AB Sahakyan, M Vendruscolo
The Journal of Chemical Physics 139 (3), 034101, 2013
Assessment of solvent effects: do weak alignment media affect the structure of the solute?
AA Shahkhatuni, AG Shahkhatuni, HA Panosyan, AB Sahakyan, ...
Magnetic Resonance in Chemistry 45 (7), 557-563, 2007
Computational studies of dielectric permittivity effects on chemical shifts of alanine dipeptide
AB Sahakyan
Chemical Physics Letters 547, 66-72, 2012
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