| Structural basis of actin filament nucleation and processive capping by a formin homology 2 domain T Otomo, DR Tomchick, C Otomo, SC Panchal, M Machius, MK Rosen Nature 433 (7025), 488-494, 2005 | 481 | 2005 |
| Structure of the human ATG12~ ATG5 conjugate required for LC3 lipidation in autophagy C Otomo, Z Metlagel, G Takaesu, T Otomo Nature structural & molecular biology 20 (1), 59-66, 2013 | 421 | 2013 |
| Structural basis of Rho GTPase-mediated activation of the formin mDia1 T Otomo, C Otomo, DR Tomchick, M Machius, MK Rosen Molecular cell 18 (3), 273-281, 2005 | 284 | 2005 |
| Segmental isotope labeling for protein NMR using peptide splicing T Yamazaki, T Otomo, N Oda, Y Kyogoku, K Uegaki, N Ito, Y Ishino, ... Journal of the American Chemical Society 120 (22), 5591-5592, 1998 | 276 | 1998 |
| The autophagic membrane tether ATG2A transfers lipids between membranes S Maeda, C Otomo, T Otomo elife 8, e45777, 2019 | 258 | 2019 |
| Structure, lipid scrambling activity and role in autophagosome formation of ATG9A S Maeda, H Yamamoto, LN Kinch, CM Garza, S Takahashi, C Otomo, ... Nature structural & molecular biology 27 (12), 1194-1201, 2020 | 216 | 2020 |
| Insights into autophagosome biogenesis from structural and biochemical analyses of the ATG2A-WIPI4 complex S Chowdhury, C Otomo, A Leitner, K Ohashi, R Aebersold, GC Lander, ... Proceedings of the National Academy of Sciences 115 (42), E9792-E9801, 2018 | 185 | 2018 |
| NMR observation of selected segments in a larger protein: central-segment isotope labeling through intein-mediated ligation T Otomo, N Ito, Y Kyogoku, T Yamazaki Biochemistry 38 (49), 16040-16044, 1999 | 162 | 1999 |
| Improved segmental isotope labeling of proteins and application to a larger protein T Otomo, K Teruya, K Uegaki, T Yamazaki, Y Kyogoku Journal of biomolecular NMR 14, 105-114, 1999 | 126 | 1999 |
| Flexible linker in the RNA polymerase alpha subunit facilitates the independent motion of the C-terminal activator contact domain YH Jeon, T Yamazaki, T Otomo, A Ishihama, Y Kyogoku Journal of molecular biology 267 (4), 953-962, 1997 | 111 | 1997 |
| Structural basis of ATG3 recognition by the autophagic ubiquitin-like protein ATG12 Z Metlagel, C Otomo, G Takaesu, T Otomo Proceedings of the National Academy of Sciences 110 (47), 18844-18849, 2013 | 91 | 2013 |
| Structure of the heterodimeric complex between CAD domains of CAD and ICAD T Otomo, H Sakahira, K Uegaki, S Nagata, T Yamazaki Nature structural biology 7 (8), 658-662, 2000 | 76 | 2000 |
| Rational design of genetically encoded fluorescence resonance energy transfer-based sensors of cellular Cdc42 signaling A Seth, T Otomo, HL Yin, MK Rosen Biochemistry 42 (14), 3997-4008, 2003 | 69 | 2003 |
| A novel mechanism of actin filament processive capping by formin: solution of the rotation paradox T Shemesh, T Otomo, MK Rosen, AD Bershadsky, MM Kozlov The Journal of cell biology 170 (6), 889-893, 2005 | 67 | 2005 |
| Crystal structure of the Formin mDia1 in autoinhibited conformation T Otomo, DR Tomchick, C Otomo, M Machius, MK Rosen PLoS One 5 (9), e12896, 2010 | 62 | 2010 |
| Structure of the CAD domain of caspase-activated DNase and interaction with the CAD domain of its inhibitor K Uegaki, T Otomo, H Sakahira, M Shimizu, N Yumoto, Y Kyogoku, ... Journal of Molecular Biology 297 (5), 1121-1128, 2000 | 46 | 2000 |
| Inhibition of autophagy by a small molecule through covalent modification of the LC3 protein S Fan, L Yue, W Wan, Y Zhang, B Zhang, C Otomo, Q Li, T Lin, J Hu, P Xu, ... Angewandte Chemie International Edition 60 (50), 26105-26114, 2021 | 38 | 2021 |
| Structural insights into E2–E3 interaction for LC3 lipidation Z Metlagel, C Otomo, K Ohashi, G Takaesu, T Otomo Autophagy 10 (3), 522-523, 2014 | 35 | 2014 |
| The rod-shaped ATG2A-WIPI4 complex tethers membranes in vitro T Otomo, S Chowdhury, GC Lander Contact 1, 2515256418819936, 2018 | 24 | 2018 |
| ATG2A transfers lipids between membranes in vitro T Otomo, S Maeda Autophagy 15 (11), 2031-2032, 2019 | 17 | 2019 |
