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Christian Jorgensen
Christian Jorgensen
Marie Sklodowska Curie Fellow, Aarhus University
Verified email at georgetown.edu - Homepage
Title
Cited by
Cited by
Year
Ribonucleotide reductase requires subunit switching in hypoxia to maintain DNA replication
IP Foskolou, C Jorgensen, KB Leszczynska, MM Olcina, H Tarhonskaya, ...
Molecular cell 66 (2), 206-220. e9, 2017
792017
An experimentally validated approach to calculate the blood-brain barrier permeability of small molecules
Y Wang, E Gallagher, C Jorgensen, EP Troendle, D Hu, PC Searson, ...
Scientific reports 9 (1), 6117, 2019
442019
A perspective on structural and computational work on collagen
C Domene, C Jorgensen, SW Abbasi
Physical Chemistry Chemical Physics 18 (36), 24802-24811, 2016
372016
2-Oxoglutarate regulates binding of hydroxylated hypoxia-inducible factor to prolyl hydroxylase domain 2
MI Abboud, TE McAllister, IKH Leung, R Chowdhury, C Jorgensen, ...
Chemical communications 54 (25), 3130-3133, 2018
312018
Lateral fenestrations in K+-channels explored using MD simulations
C Jorgensen, L Darré, V Oakes, R Torella, D Pryde, C Domene
Molecular Pharmaceutics, 2016
272016
13 C-Carbamylation as a mechanistic probe for the inhibition of class D β-lactamases by avibactam and halide ions
CT Lohans, DY Wang, C Jorgensen, ST Cahill, IJ Clifton, MA McDonough, ...
Organic & biomolecular chemistry 15 (28), 6024-6032, 2017
252017
Mechanism of molecular oxygen diffusion in a hypoxia-sensing prolyl hydroxylase using multiscale simulation
C Domene, C Jorgensen, CJ Schofield
Journal of the American Chemical Society 142 (5), 2253-2263, 2020
242020
In silico identification of PAP-1 binding sites in the Kv1. 2 potassium channel
C Jorgensen, L Darre, K Vanommeslaeghe, K Omoto, D Pryde, ...
Molecular pharmaceutics 12 (4), 1299-1307, 2015
242015
Energetics of ion permeation in an open-activated TRPV1 channel
C Jorgensen, S Furini, C Domene
Biophysical Journal 111 (6), 1214-1222, 2016
232016
Location and character of volatile general anesthetics binding sites in the transmembrane domain of TRPV1
C Jorgensen, C Domene
Molecular pharmaceutics 15 (9), 3920-3930, 2018
142018
Atomistic model of solute transport across the blood–brain barrier
C Jorgensen, MB Ulmschneider, PC Searson
ACS omega 7 (1), 1100-1112, 2021
72021
Quantifying the Binding Interaction between the Hypoxia-Inducible Transcription Factor and the von Hippel–Lindau Suppressor
C Domene, C Jorgensen, K Vanommeslaeghe, CJ Schofield, ...
Journal of chemical theory and computation 11 (8), 3946-3954, 2015
32015
Computer Simulations of Membrane Proteins
C Jorgensen, V Oakes, C Domene
Membrane Organization and Dynamics, 351-374, 2017
22017
A least-squares-fitting procedure for an efficient preclinical ranking of passive transport across the blood–brain barrier endothelium
C Jorgensen, EP Troendle, JP Ulmschneider, PC Searson, ...
Journal of Computer-Aided Molecular Design 37 (11), 537-549, 2023
12023
The two enantiomers of 2-hydroxyglutarate differentially regulate cytotoxic T cell function
IP Foskolou, PP Cunha, E Sánchez-López, EA Minogue, BP Nicolet, ...
Cell reports 42 (9), 2023
12023
Tracking Policy Implications and Impacts of the COVID-19 Pandemic and Related Executive Actions on a Sampling of Foreign-born Early Career Researchers in the US
C Jorgensen, MA Astore, F Sancheznieto, S Vedachalam, A Mughal, ...
OSF Preprints, 2022
12022
Simulations of Active Transport Across the Blood-Brain Barrier
C Jorgensen, M Ulmschneider, PC Searson
Biophysical Journal 118 (3), 527a, 2020
12020
Modeling Substrate Entry into the P-Glycoprotein Efflux Pump at the Blood–Brain Barrier
C Jorgensen, MB Ulmschneider, PC Searson
Journal of medicinal chemistry 66 (24), 16615-16627, 2023
2023
Towards a multiscale model of P-glycoprotein efflux
C Jorgensen, KB Pedersen, MB Ulmschneider, B Schiøtt, PC Searson
Biophysical Journal 122 (3), 530a, 2023
2023
An atomistic model of the human stratum corneum: permeation through the long periodicity phase—effect of a pro-penetrant
C Jorgensen, F Léonforte, GS Luengo, S Gregoire, B Biatry, PD Olmsted, ...
Biophysical Journal 121 (3), 35a, 2022
2022
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