| RTEL1 maintains genomic stability by suppressing homologous recombination LJ Barber, JL Youds, JD Ward, MJ McIlwraith, NJ O'Neil, MIR Petalcorin, ... Cell 135 (2), 261-271, 2008 | 448 | 2008 |
| Secondary mutations in BRCA2 associated with clinical resistance to a PARP inhibitor LJ Barber, S Sandhu, L Chen, J Campbell, I Kozarewa, K Fenwick, ... The Journal of pathology 229 (3), 422-429, 2013 | 377 | 2013 |
| Cancer evolution and the limits of predictability in precision cancer medicine KA Lipinski, LJ Barber, MN Davies, M Ashenden, A Sottoriva, M Gerlinger Trends in cancer 2 (1), 49-63, 2016 | 290 | 2016 |
| FANCJ is a structure-specific DNA helicase associated with the maintenance of genomic G/C tracts TBC London, LJ Barber, G Mosedale, GP Kelly, S Balasubramanian, ... Journal of biological chemistry 283 (52), 36132-36139, 2008 | 264 | 2008 |
| A critical role for the ubiquitin-conjugating enzyme Ubc13 in initiating homologous recombination GY Zhao, E Sonoda, LJ Barber, H Oka, Y Murakawa, K Yamada, T Ikura, ... Molecular cell 25 (5), 663-675, 2007 | 262 | 2007 |
| Methotrexate induces oxidative DNA damage and is selectively lethal to tumour cells with defects in the DNA mismatch repair gene MSH2 SA Martin, A McCarthy, LJ Barber, DJ Burgess, S Parry, CJ Lord, ... EMBO molecular medicine 1 (6‐7), 323-337, 2009 | 210 | 2009 |
| Genomic and transcriptomic determinants of therapy resistance and immune landscape evolution during anti-EGFR treatment in colorectal cancer A Woolston, K Khan, G Spain, LJ Barber, B Griffiths, R Gonzalez-Exposito, ... Cancer cell 36 (1), 35-50. e9, 2019 | 207 | 2019 |
| Efficacy of chemotherapy in BRCA1/2 mutation carrier ovarian cancer in the setting of PARP inhibitor resistance: a multi-institutional study JE Ang, C Gourley, CB Powell, H High, R Shapira-Frommer, ... Clinical Cancer Research 19 (19), 5485-5493, 2013 | 152 | 2013 |
| Inhibitors of the proteasome suppress homologous DNA recombination in mammalian cells Y Murakawa, E Sonoda, LJ Barber, W Zeng, K Yokomori, H Kimura, ... Cancer research 67 (18), 8536-8543, 2007 | 128 | 2007 |
| HCLK2 is essential for the mammalian S-phase checkpoint and impacts on Chk1 stability SJ Collis, LJ Barber, AJ Clark, JS Martin, JD Ward, SJ Boulton Nature cell biology 9 (4), 391, 2007 | 126 | 2007 |
| DOG-1 is the Caenorhabditis elegans BRIP1/FANCJ homologue and functions in interstrand cross-link repair JL Youds, LJ Barber, JD Ward, SJ Collis, NJ O'Neil, SJ Boulton, AM Rose Molecular and cellular biology 28 (5), 1470-1479, 2008 | 115 | 2008 |
| Replication blocking lesions present a unique substrate for homologous recombination JD Ward, LJ Barber, MIR Petalcorin, J Yanowitz, SJ Boulton The EMBO journal 26 (14), 3384-3396, 2007 | 96 | 2007 |
| Poly (ADP-ribose) polymerase (PARP) inhibitors for the treatment of advanced germline BRCA2 mutant prostate cancer SK Sandhu, A Omlin, L Hylands, S Miranda, LJ Barber, R Riisnaes, ... Annals of oncology 24 (5), 1416-1418, 2013 | 90 | 2013 |
| C. elegans FANCD2 responds to replication stress and functions in interstrand cross-link repair SJ Collis, LJ Barber, JD Ward, JS Martin, SJ Boulton DNA repair 5 (11), 1398-1406, 2006 | 83 | 2006 |
| DNA interstrand cross-link repair in the Saccharomyces cerevisiae cell cycle: overlapping roles for PSO2 (SNM1) with MutS factors and EXO1 during S phase LJ Barber, TA Ward, JA Hartley, PJ McHugh Molecular and cellular biology 25 (6), 2297-2309, 2005 | 83 | 2005 |
| CEA expression heterogeneity and plasticity confer resistance to the CEA-targeting bispecific immunotherapy antibody cibisatamab (CEA-TCB) in patient-derived colorectal cancer … R Gonzalez-Exposito, M Semiannikova, B Griffiths, K Khan, LJ Barber, ... Journal for immunotherapy of cancer 7 (1), 101, 2019 | 78 | 2019 |
| Dissecting cancer evolution at the macro-heterogeneity and micro-heterogeneity scale LJ Barber, MN Davies, M Gerlinger Current opinion in genetics & development 30, 1-6, 2015 | 75 | 2015 |
| Human SNM1A suppresses the DNA repair defects of yeast pso2 mutants A Hazrati, M Ramis-Castelltort, S Sarkar, LJ Barber, CJ Schofield, ... DNA repair 7 (2), 230-238, 2008 | 72 | 2008 |
| Extreme intratumour heterogeneity and driver evolution in mismatch repair deficient gastro-oesophageal cancer K Von Loga, A Woolston, M Punta, LJ Barber, B Griffiths, M Semiannikova, ... BioRxiv, 755199, 2019 | 61 | 2019 |
| The MRT‐1 nuclease is required for DNA crosslink repair and telomerase activity in vivo in Caenorhabditis elegans B Meier, LJ Barber, Y Liu, L Shtessel, SJ Boulton, A Gartner, S Ahmed The EMBO journal 28 (22), 3549-3563, 2009 | 60 | 2009 |
