| Straightforward Synthesis of (S)- and (R)-α-Trifluoromethyl Proline from Chiral Oxazolidines Derived from Ethyl Trifluoropyruvate G Chaume, MC Van Severen, S Marinkovic, T Brigaud Organic Letters 8 (26), 6123-6126, 2006 | 111 | 2006 |
| Iodocyclization of Chiral CF3-Allylmorpholinones: A Versatile Strategy for the Synthesis of Enantiopure α-Tfm-Prolines and α-Tfm-Dihydroxyprolines C Caupène, G Chaume, L Ricard, T Brigaud Organic Letters 11 (1), 209-212, 2009 | 74 | 2009 |
| Synthesis of 2-trifluoromethyl-1, 3-oxazolidines as hydrolytically stable pseudoprolines G Chaume, O Barbeau, P Lesot, T Brigaud The Journal of Organic Chemistry 75 (12), 4135-4145, 2010 | 53 | 2010 |
| Highly Diastereoselective α-Hydroxylation of Fox Chiral Auxiliary-Based Amide Enolates with Molecular Oxygen H Lubin, A Tessier, G Chaume, J Pytkowicz, T Brigaud Organic letters 12 (7), 1496-1499, 2010 | 49 | 2010 |
| Synthesis of an MIF-1 analogue containing enantiopure (S)-α-trifluoromethyl-proline and biological evaluation on nociception I Jlalia, N Lensen, G Chaume, E Dzhambazova, L Astasidi, R Hadjiolova, ... European Journal of Medicinal Chemistry 62, 122-129, 2013 | 45 | 2013 |
| Approach Toward the Total Synthesis of Griseoviridin: Formation of Thioethynyl and Thiovinyl Ether-Containing Nine-Membered Lactones through a Thioalkynylation … C Kuligowski, S Bezzenine-Lafollée, G Chaume, J Mahuteau, JC Barrière, ... The Journal of Organic Chemistry 67 (13), 4565-4568, 2002 | 44 | 2002 |
| Concise access to enantiopure (S)-and (R)-α-trifluoromethyl pyroglutamic acids from ethyl trifluoropyruvate-based chiral CF3-oxazolidines (Fox) G Chaume, MC Van Severen, L Ricard, T Brigaud Journal of Fluorine Chemistry 129 (11), 1104-1109, 2008 | 40 | 2008 |
| Incorporation of CF3–Pseudoprolines into Peptides: A Methodological Study G Chaume, J Simon, C Caupène, N Lensen, E Miclet, T Brigaud The Journal of Organic Chemistry 78 (20), 10144-10153, 2013 | 31 | 2013 |
| Local Control of the Cis–Trans Isomerization and Backbone Dihedral Angles in Peptides Using Trifluoromethylated Pseudoprolines D Feytens, G Chaume, G Chassaing, S Lavielle, T Brigaud, BJ Byun, ... The Journal of Physical Chemistry B 116 (13), 4069-4079, 2012 | 31 | 2012 |
| Synthesis of Enantiopure trans-2,5-Disubstituted Trifluoromethylpyrrolidines and (2S,5R)-5-Trifluoromethylproline H Lubin, J Pytkowicz, G Chaume, G Sizun-Thome, T Brigaud The Journal of Organic Chemistry 80 (5), 2700-2708, 2015 | 30 | 2015 |
| Concise synthesis of enantiopure (S)- and (R)-α-trifluoromethyl aspartic acid and α-trifluoromethyl serine from chiral trifluoromethyl oxazolidines (Fox) via a … J Simon, TT Nguyen, E Chelain, N Lensen, J Pytkowicz, G Chaume, ... Tetrahedron: Asymmetry 22 (3), 309-314, 2011 | 30 | 2011 |
| Convenient Synthesis of N‐Terminal Tfm‐Dipeptides from Unprotected Enantiopure α‐Tfm‐Proline and α‐Tfm‐Alanine G Chaume, N Lensen, C Caupène, T Brigaud European Journal of Organic Chemistry 2009 (33), 5717-5724, 2009 | 30 | 2009 |
| Trifluoromethylated proline analogues as efficient tools to enhance the hydrophobicity and to promote passive diffusion transport of the L-prolyl-L-leucyl glycinamide (PLG … M Oliver, C Gadais, J García-Pindado, M Teixidó, N Lensen, G Chaume, ... RSC advances 8 (26), 14597-14602, 2018 | 28 | 2018 |
| CF 2 H as a hydrogen bond donor group for the fine tuning of peptide bond geometry with difluoromethylated pseudoprolines N Malquin, K Rahgoshay, N Lensen, G Chaume, E Miclet, T Brigaud Chemical communications 55 (83), 12487-12490, 2019 | 25 | 2019 |
| Homochiral versus heterochiral trifluoromethylated pseudoproline containing dipeptides: a powerful tool to switch the prolyl-amide bond conformation G Chaume, J Simon, N Lensen, J Pytkowicz, T Brigaud, E Miclet The Journal of Organic Chemistry 82 (24), 13602-13608, 2017 | 19 | 2017 |
| Incorporation of trifluoromethylated proline and surrogates into peptides: application to the synthesis of fluorinated analogues of the neuroprotective glycine-proline … J Simon, J Pytkowicz, N Lensen, G Chaume, T Brigaud The Journal of Organic Chemistry 81 (13), 5381-5392, 2016 | 18 | 2016 |
| Orthogonal 19F‐Labeling for Solid‐State NMR Spectroscopy Reveals the Conformation and Orientation of Short Peptaibols in Membranes SL Grage, S Kara, A Bordessa, V Doan, F Rizzolo, M Putzu, T Kubař, ... Chemistry–A European Journal 24 (17), 4328-4335, 2018 | 17 | 2018 |
| Zinc-acetic acid reductive cyclisation in a two-step synthesis of the S1-N10 nine-membered lactone core of ent-griseoviridin G Chaume, C Kuligowski, S Bezzenine-Laffolée, L Ricard, A Pancrazi, ... Synthesis, 3029-3036, 2004 | 13 | 2004 |
| Trifluoromethylated Proline Surrogates as Part of “Pro–Pro” Turn‐Inducing Templates C Gadais, K Van Holsbeeck, SLC Moors, D Buyst, K Feher, K Van Hecke, ... ChemBioChem 20 (19), 2513-2518, 2019 | 11 | 2019 |
| Conformational properties of peptides incorporating a fluorinated pseudoproline residue G Chaume, D Feytens, G Chassaing, S Lavielle, T Brigaud, E Miclet New Journal of Chemistry 37 (5), 1336-1342, 2013 | 11 | 2013 |
