The membrane actions of anesthetics and tranquilizers P Seeman Pharmacol rev 24 (4), 583-655, 1972 | 3257 | 1972 |
Brain dopamine recepotrs P Seeman Pharmacol Rev 32, 229-313, 1981 | 2707 | 1981 |
Cloning of the gene for a human dopamine D4 receptor with high affinity for the antipsychotic clozapine HHM Van Tol, JR Bunzow, HC Guan, RK Sunahara, P Seeman, ... Nature 350 (6319), 610-614, 1991 | 2595 | 1991 |
Antipsychotic drug doses and neuroleptic/dopamine receptors P Seeman, T Lee, M Chau-Wong, K Wong Nature 261 (5562), 717-719, 1976 | 2199 | 1976 |
Does Fast Dissociation From the Dopamine D2 Receptor Explain the Action of Atypical Antipsychotics?: A New Hypothesis S Kapur, P Seeman American Journal of Psychiatry 158 (3), 360-369, 2001 | 1645 | 2001 |
Cloning of the gene for a human dopamine D5 receptor with higher affinity for dopamine than D1 RK Sunahara, HC Guan, BF O'Dowd, P Seeman, LG Laurier, G Ng, ... Nature 350 (6319), 614-619, 1991 | 1422 | 1991 |
Radioreceptor binding profile of the atypical antipsychotic olanzapine FP Bymaster, DO Calligaro, JF Falcone, RD Marsh, NA Moore, NC Tye, ... Neuropsychopharmacology 14 (2), 87-96, 1996 | 1375 | 1996 |
Atypical antipsychotics: mechanism of action P Seeman The Canadian Journal of Psychiatry 47 (1), 27-38, 2002 | 1277 | 2002 |
Multiple dopamine D4 receptor variants in the human population HHMV Tol, CM Wu, HC Guan, K Ohara, JR Bunzow, O Civelli, J Kennedy, ... Nature 358 (6382), 149-152, 1992 | 1230 | 1992 |
Antipsychotic drugs: direct correlation between clinical potency and presynaptic action on dopamine neurons P Seeman, T Lee Science 188 (4194), 1217-1219, 1975 | 1214 | 1975 |
Dopamine receptors and the dopamine hypothesis of schizophrenia P Seeman Synapse 1 (2), 133-152, 1987 | 1175 | 1987 |
Dopamine receptor pharmacology P Seeman, HHM Van Tol Trends in pharmacological sciences 15 (7), 264-270, 1994 | 1157 | 1994 |
Brain receptors for antipsychotic drugs and dopamine: direct binding assays. P Seeman, M Chau-Wong, J Tedesco, K Wong Proceedings of the National Academy of Sciences 72 (11), 4376-4380, 1975 | 1005 | 1975 |
Dopamine D4 receptors elevated in schizophrenia P Seeman, HC Guan, HHM Van Tol Nature 365 (6445), 441-445, 1993 | 887 | 1993 |
Dopamine receptor sequences. Therapeutic levels of neuroleptics occupy D2 receptors, clozapine occupies D4. P Seeman Neuropsychopharmacology: official publication of the American College of …, 1992 | 655 | 1992 |
D1 and D2 dopamine receptor mRNA in rat brain. DM Weiner, AI Levey, RK Sunahara, HB Niznik, BF O'Dowd, P Seeman, ... Proceedings of the national academy of sciences 88 (5), 1859-1863, 1991 | 636 | 1991 |
Human dopamine D1 receptor encoded by an intronless gene on chromosome 5 RK Sunahara, HB Niznik, DM Weiner, TM Stormann, MR Brann, ... Nature 347 (6288), 80-83, 1990 | 622 | 1990 |
Receptor basis for dopaminergic supersensitivity in Parkinson's disease T Lee, P Seeman, A Rajput, IJ FARLEY, O Hornykiewicz Nature 273 (5657), 59-61, 1978 | 559 | 1978 |
NMDA receptor antagonists ketamine and PCP have direct effects on the dopamine D2 and serotonin 5-HT2 receptors—implications for models of schizophrenia S Kapur, P Seeman Molecular psychiatry 7 (8), 837-844, 2002 | 556 | 2002 |
A positron emission tomography study of quetiapine in schizophrenia: a preliminary finding of an antipsychotic effect with only transiently high dopamine D2 receptor occupancy S Kapur, R Zipursky, C Jones, CS Shammi, G Remington, P Seeman Archives of general psychiatry 57 (6), 553-559, 2000 | 545 | 2000 |