| The two-pore channel TPCN2 mediates NAADP-dependent Ca2+-release from lysosomal stores X Zong, M Schieder, H Cuny, S Fenske, C Gruner, K Rötzer, O Griesbeck, ... Pflügers Archiv-European Journal of Physiology 458, 891-899, 2009 | 307 | 2009 |
| High susceptibility to fatty liver disease in two-pore channel 2-deficient mice C Grimm, LM Holdt, CC Chen, S Hassan, C Müller, S Jörs, H Cuny, ... Nature communications 5 (1), 4699, 2014 | 212 | 2014 |
| Switching off calcium-dependent inactivation in l-type calcium channels by an autoinhibitory domain C Wahl-Schott, L Baumann, H Cuny, C Eckert, K Griessmeier, M Biel Proceedings of the National Academy of Sciences 103 (42), 15657-15662, 2006 | 110 | 2006 |
| A screening approach to identify clinically actionable variants causing congenital heart disease in exome data JO Szot, H Cuny, GM Blue, DT Humphreys, E Ip, K Harrison, GF Sholler, ... Circulation: Genomic and Precision Medicine 11 (3), e001978, 2018 | 76 | 2018 |
| Identification of clinically actionable variants from genome sequencing of families with congenital heart disease D Alankarage, E Ip, JO Szot, J Munro, GM Blue, K Harrison, H Cuny, ... Genetics in Medicine 21 (5), 1111-1120, 2019 | 71 | 2019 |
| Isolation and characterization of α-conotoxin LsIA with potent activity at nicotinic acetylcholine receptors MC Inserra, SN Kompella, I Vetter, A Brust, NL Daly, H Cuny, DJ Craik, ... Biochemical pharmacology 86 (6), 791-799, 2013 | 63 | 2013 |
| γ-Aminobutyric acid type B (GABAB) receptor expression is needed for inhibition of N-type (Cav2. 2) calcium channels by analgesic α-conotoxins H Cuny, A De Faoite, TG Huynh, T Yasuda, G Berecki, DJ Adams Journal of Biological Chemistry 287 (28), 23948-23957, 2012 | 57 | 2012 |
| Identifying key amino acid residues that affect α-conotoxin AuIB inhibition of α3β4 nicotinic acetylcholine receptors AA Grishin, H Cuny, A Hung, RJ Clark, A Brust, K Akondi, PF Alewood, ... Journal of Biological Chemistry 288 (48), 34428-34442, 2013 | 50 | 2013 |
| Novel mechanism of voltage-gated N-type (Cav2. 2) calcium channel inhibition revealed through α-conotoxin Vc1. 1 activation of the GABAB receptor TG Huynh, H Cuny, PA Slesinger, DJ Adams Molecular Pharmacology 87 (2), 240-250, 2015 | 47 | 2015 |
| NAD deficiency due to environmental factors or gene–environment interactions causes congenital malformations and miscarriage in mice H Cuny, M Rapadas, J Gereis, EMMA Martin, RB Kirk, H Shi, ... Proceedings of the National Academy of Sciences 117 (7), 3738-3747, 2020 | 46 | 2020 |
| Differential Cav2. 1 and Cav2. 3 channel inhibition by baclofen and α-conotoxin Vc1. 1 via GABAB receptor activation G Berecki, JR McArthur, H Cuny, RJ Clark, DJ Adams Biophysical Journal 106 (2), 330a, 2014 | 44 | 2014 |
| Calmodulin is a functional regulator of Cav1. 4 L-type Ca2+ channels K Griessmeier, H Cuny, K Rötzer, O Griesbeck, H Harz, M Biel, ... Journal of Biological Chemistry 284 (43), 29809-29816, 2009 | 42 | 2009 |
| Bi-allelic mutations in NADSYN1 cause multiple organ defects and expand the genotypic spectrum of congenital NAD deficiency disorders JO Szot, C Campagnolo, Y Cao, KR Iyer, H Cuny, T Drysdale, ... The American Journal of Human Genetics 106 (1), 129-136, 2020 | 37 | 2020 |
| α‐Conotoxins active at α3‐containing nicotinic acetylcholine receptors and their molecular determinants for selective inhibition H Cuny, R Yu, HS Tae, SN Kompella, DJ Adams British Journal of Pharmacology 175 (11), 1855-1868, 2018 | 27 | 2018 |
| Molecular basis for differential sensitivity of α-conotoxin RegIIA at rat and human neuronal nicotinic acetylcholine receptors SN Kompella, H Cuny, A Hung, DJ Adams Molecular pharmacology 88 (6), 993-1001, 2015 | 27 | 2015 |
| Kv3.1 channels stimulate adult neural precursor cell proliferation and neuronal differentiation T Yasuda, H Cuny, DJ Adams The Journal of physiology 591 (10), 2579-2591, 2013 | 25 | 2013 |
| Key structural determinants in the agonist binding loops of human β2 and β4 nicotinic acetylcholine receptor subunits contribute to α3β4 subtype selectivity of α-conotoxins H Cuny, SN Kompella, HS Tae, R Yu, DJ Adams Journal of Biological Chemistry 291 (45), 23779-23792, 2016 | 23 | 2016 |
| CHDgene: A Curated Database for Congenital Heart Disease Genes A Yang, D Alankarage, H Cuny, EKK Ip, M Almog, J Lu, D Das, A Enriquez, ... Circulation: Genomic and Precision Medicine 15 (3), e003539, 2022 | 12 | 2022 |
| Simultaneous quantification of 26 NAD-related metabolites in plasma, blood, and liver tissue using UHPLC-MS/MS H Cuny, E Kristianto, MP Hodson, SL Dunwoodie Analytical Biochemistry 633, 114409, 2021 | 8 | 2021 |
| Maternal heterozygosity of Slc6a19 causes metabolic perturbation and congenital NAD deficiency disorder in mice H Cuny, K Bozon, RB Kirk, DZ Sheng, S Bröer, SL Dunwoodie Disease Models & Mechanisms 16 (5), dmm049647, 2023 | 7 | 2023 |
