Следене
Michael Van Meter
Michael Van Meter
Потвърден имейл адрес: regeneron.com
Заглавие
Позовавания
Позовавания
Година
SIRT6 promotes DNA repair under stress by activating PARP1
Z Mao, C Hine, X Tian, M Van Meter, M Au, A Vaidya, A Seluanov, ...
Science 332 (6036), 1443-1446, 2011
8972011
SIRT6 represses LINE1 retrotransposons by ribosylating KAP1 but this repression fails with stress and age
M Van Meter, M Kashyap, S Rezazadeh, AJ Geneva, TD Morello, ...
Nature communications 5 (1), 5011, 2014
3972014
LINE1 derepression in aged wild-type and SIRT6-deficient mice drives inflammation
M Simon, M Van Meter, J Ablaeva, Z Ke, RS Gonzalez, T Taguchi, ...
Cell metabolism 29 (4), 871-885. e5, 2019
3432019
Sirtuin 6 (SIRT6) rescues the decline of homologous recombination repair during replicative senescence
Z Mao, X Tian, M Van Meter, Z Ke, V Gorbunova, A Seluanov
Proceedings of the National Academy of Sciences 109 (29), 11800-11805, 2012
1892012
SIRT6 overexpression induces massive apoptosis in cancer cells but not in normal cells
M Van Meter, Z Mao, V Gorbunova, A Seluanov
Cell cycle 10 (18), 3153-3158, 2011
1802011
JNK phosphorylates SIRT6 to stimulate DNA double-strand break repair in response to oxidative stress by recruiting PARP1 to DNA breaks
M Van Meter, M Simon, G Tombline, A May, TD Morello, BP Hubbard, ...
Cell reports 16 (10), 2641-2650, 2016
1332016
SIRT6 rescues the age related decline in base excision repair in a PARP1-dependent manner
Z Xu, L Zhang, W Zhang, DU Meng, H Zhang, Y Jiang, X Xu, M Van Meter, ...
Cell cycle 14 (2), 269-276, 2015
1122015
Common and rare variant associations with clonal haematopoiesis phenotypes
MD Kessler, A Damask, S O’Keeffe, N Banerjee, D Li, K Watanabe, ...
Nature 612 (7939), 301-309, 2022
892022
Repairing split ends: SIRT6, mono-ADP ribosylation and DNA repair
M Van Meter, Z Mao, V Gorbunova, A Seluanov
Aging (Albany NY) 3 (9), 829, 2011
832011
A rare human centenarian variant of SIRT6 enhances genome stability and interaction with Lamin A
M Simon, J Yang, J Gigas, EJ Earley, E Hillpot, L Zhang, M Zagorulya, ...
The EMBO Journal 41 (21), e110393, 2022
212022
IGF1R levels in the brain negatively correlate with longevity in 16 rodent species
J Azpurua, JN Yang, M Van Meter, Z Liu, J Kim, AABL Ladd, AA Coppi, ...
Aging (Albany NY) 5 (4), 304, 2013
202013
Exome sequencing of 628,388 individuals identifies common and rare variant associations with clonal hematopoiesis phenotypes
MD Kessler, A Damask, S O’Keeffe, M Van Meter, N Banerjee, S Semrau, ...
MedRxiv, 2021.12. 29.21268342, 2022
152022
SIRT6: a promising target for cancer prevention and therapy
M Van Meter, V Gorbunova, A Seluanov
Anticancer Genes, 181-196, 2014
152014
Effects of an unusual poison identify a lifespan role for Topoisomerase 2 in Saccharomyces cerevisiae
G Tombline, JI Millen, B Polevoda, M Rapaport, B Baxter, M Van Meter, ...
Aging (Albany NY) 9 (1), 68, 2017
132017
Therapeutic targeting of Notch signaling and immune checkpoint blockade in a spontaneous, genetically heterogeneous mouse model of T-cell acute lymphoblastic leukemia
J Gao, M Van Meter, S Hernandez Lopez, G Chen, Y Huang, S Ren, ...
Disease models & mechanisms 12 (9), dmm040931, 2019
112019
Forever young? Exploring the link between rapamycin, longevity and cancer
M Van Meter, A Seluanov, V Gorbunova
Cell Cycle 11 (23), 4296-4297, 2012
62012
A rare human centenarian variant of SIRT6 enhances genome stability and interaction with Lamin A
M Simon, J Yang, J Gigas, EJ Earley, E Hillpot, L Zhang, M Zagorulya, ...
The EMBO Journal 42 (3), e113326, 2023
32023
Comparative Biology of Aging: Insights from Long-Lived Rodent Species
M Van Meter, V Gorbunova, A Seluanov
Handbook of the Biology of Aging 8, 305–324, 2015
32015
Inhibition of retrotransposition improves health and extends lifespan of SIRT6 knockout mice
M Simon, MV Meter, J Ablaeva, Z Ke, RS Gonzalez, T Taguchi, MD Cecco, ...
bioRxiv, 460808, 2018
22018
Anti-ptcra antibody-drug conjugates and uses thereof
F Kuhnert, M Van Meter, T Nittoli
US Patent App. 18/482,448, 2024
2024
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