Следене
Brion Murray
Brion Murray
Riva Therapeutics
Потвърден имейл адрес: rivathera.com
Заглавие
Позовавания
Позовавания
Година
SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase
BL Bennett, DT Sasaki, BW Murray, EC O'Leary, ST Sakata, W Xu, ...
Proceedings of the National Academy of Sciences 98 (24), 13681-13686, 2001
30442001
IKK-1 and IKK-2: cytokine-activated IκB kinases essential for NF-κB activation
F Mercurio, H Zhu, BW Murray, A Shevchenko, BL Bennett, J Li, ...
Science 278 (5339), 860-866, 1997
27081997
Nonclinical antiangiogenesis and antitumor activities of axitinib (AG-013736), an oral, potent, and selective inhibitor of vascular endothelial growth factor receptor tyrosine …
DD Hu-Lowe, HY Zou, ML Grazzini, ME Hallin, GR Wickman, ...
Clinical Cancer Research 14 (22), 7272-7283, 2008
7052008
Molecular conformations, interactions, and properties associated with drug efficiency and clinical performance among VEGFR TK inhibitors
M McTigue, BW Murray, JH Chen, YL Deng, J Solowiej, RS Kania
Proceedings of the National Academy of Sciences 109 (45), 18281-18289, 2012
4812012
IκB kinase (IKK)-associated protein 1, a common component of the heterogeneous IKK complex
F Mercurio, BW Murray, A Shevchenko, BL Bennett, DB Young, JW Li, ...
Molecular and cellular biology 19 (2), 1526-1538, 1999
4581999
Discovery of ketone-based covalent inhibitors of coronavirus 3CL proteases for the potential therapeutic treatment of COVID-19
RL Hoffman, RS Kania, MA Brothers, JF Davies, RA Ferre, KS Gajiwala, ...
Journal of medicinal chemistry 63 (21), 12725-12747, 2020
4522020
Spectrum and degree of CDK drug interactions predicts clinical performance
P Chen, NV Lee, W Hu, M Xu, RA Ferre, H Lam, S Bergqvist, J Solowiej, ...
Molecular cancer therapeutics 15 (10), 2273-2281, 2016
3712016
Small-molecule p21-activated kinase inhibitor PF-3758309 is a potent inhibitor of oncogenic signaling and tumor growth
BW Murray, C Guo, J Piraino, JK Westwick, C Zhang, J Lamerdin, ...
Proceedings of the National Academy of Sciences 107 (20), 9446-9451, 2010
3402010
PAK signaling in oncogenesis
PR Molli, DQ Li, BW Murray, SK Rayala, R Kumar
Oncogene 28 (28), 2545-2555, 2009
2732009
Axitinib effectively inhibits BCR-ABL1 (T315I) with a distinct binding conformation
T Pemovska, E Johnson, M Kontro, GA Repasky, J Chen, P Wells, ...
Nature 519 (7541), 102-105, 2015
2692015
Covalent EGFR inhibitor analysis reveals importance of reversible interactions to potency and mechanisms of drug resistance
PA Schwartz, P Kuzmic, J Solowiej, S Bergqvist, B Bolanos, C Almaden, ...
Proceedings of the National Academy of Sciences 111 (1), 173-178, 2014
2682014
JNKK1 organizes a MAP kinase module through specific and sequential interactions with upstream and downstream components mediated by its amino-terminal extension
Y Xia, Z Wu, B Su, B Murray, M Karin
Genes & development 12 (21), 3369-3381, 1998
2531998
p38-2, a novel mitogen-activated protein kinase with distinct properties
B Stein, MX Yang, DB Young, R Janknecht, T Hunter, BW Murray, ...
Journal of Biological Chemistry 272 (31), 19509-19517, 1997
2461997
Protein kinase biochemistry and drug discovery
PA Schwartz, BW Murray
Bioorganic chemistry 39 (5-6), 192-210, 2011
2232011
Mechanism of human α-1, 3-fucosyltransferase V: glycosidic cleavage occurs prior to nucleophilic attack
BW Murray, V Wittmann, MD Burkart, SC Hung, CH Wong
Biochemistry 36 (4), 823-831, 1997
2091997
Chemo-enzymatic synthesis of fluorinated sugar nucleotide: useful mechanistic probes for glycosyltransferases
MD Burkart, SP Vincent, A Düffels, BW Murray, SV Ley, CH Wong
Bioorganic & medicinal chemistry 8 (8), 1937-1946, 2000
1902000
Mechanism and specificity of human α-1, 3-fucosyltransferase V
BW Murray, S Takayama, J Schultz, CH Wong
Biochemistry 35 (34), 11183-11195, 1996
1711996
Synergistic inhibition of human α-1, 3-fucosyltransferase V
L Qiao, BW Murray, M Shimazaki, J Schultz, CH Wong
Journal of the American Chemical Society 118 (33), 7653-7662, 1996
1611996
Discovery of a Novel and Selective Indoleamine 2,3-Dioxygenase (IDO-1) Inhibitor 3-(5-Fluoro-1H-indol-3-yl)pyrrolidine-2,5-dione (EOS200271/PF-06840003) and …
S Crosignani, P Bingham, P Bottemanne, H Cannelle, S Cauwenberghs, ...
Journal of medicinal chemistry 60 (23), 9617-9629, 2017
1352017
Enzymatic characterization of c-Met receptor tyrosine kinase oncogenic mutants and kinetic studies with aminopyridine and triazolopyrazine inhibitors
SL Timofeevski, MA McTigue, K Ryan, J Cui, HY Zou, JX Zhu, F Chau, ...
Biochemistry 48 (23), 5339-5349, 2009
1132009
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