Shozeb Haider
Shozeb Haider
UCL School of Pharmacy
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Contribution of rare inherited and de novo variants in 2,871 congenital heart disease probands
SC Jin, J Homsy, S Zaidi, Q Lu, S Morton, SR DePalma, X Zeng, H Qi, ...
Nature genetics 49 (11), 1593-1601, 2017
Crystal structure of the potassium form of an Oxytricha nova G-quadruplex
S Haider, GN Parkinson, S Neidle
Journal of Molecular Biology 320 (2), 189-200, 2002
Structure of a G-quadruplex–ligand complex
SM Haider, GN Parkinson, S Neidle
Journal of molecular biology 326 (1), 117-125, 2003
Functional analysis of a structural model of the ATP‐binding site of the KATP channel Kir6. 2 subunit
JF Antcliff, S Haider, P Proks, MSP Sansom, FM Ashcroft
The EMBO journal 24 (2), 229-239, 2005
Identification of genetic variants associated with Huntington's disease progression: a genome-wide association study
DJH Moss, AF Pardiņas, D Langbehn, K Lo, BR Leavitt, R Roos, A Durr, ...
The Lancet Neurology 16 (9), 701-711, 2017
A crystallographic and modelling study of a human telomeric RNA (TERRA) quadruplex
GW Collie, SM Haider, S Neidle, GN Parkinson
Nucleic acids research 38 (16), 5569-5580, 2010
Molecular dynamics and principal components analysis of human telomeric quadruplex multimers
S Haider, GN Parkinson, S Neidle
Biophysical journal 95 (1), 296-311, 2008
Blocking FSH induces thermogenic adipose tissue and reduces body fat
P Liu, Y Ji, T Yuen, E Rendina-Ruedy, VE DeMambro, S Dhawan, ...
Nature 546 (7656), 107-112, 2017
Sequence occurrence and structural uniqueness of a G-quadruplex in the human c-kit promoter
AK Todd, SM Haider, GN Parkinson, S Neidle
Nucleic acids research 35 (17), 5799-5808, 2007
Targeting human gastrointestinal stromal tumor cells with a quadruplex-binding small molecule
M Gunaratnam, S Swank, SM Haider, K Galesa, AP Reszka, M Beltran, ...
Journal of medicinal chemistry 52 (12), 3774-3783, 2009
Activation of tumor suppressor protein PP2A inhibits KRAS-driven tumor growth
J Sangodkar, A Perl, R Tohme, J Kiselar, DB Kastrinsky, N Zaware, ...
The Journal of clinical investigation 127 (6), 2081-2090, 2017
Tri-and tetra-substituted naphthalene diimides as potent G-quadruplex ligands
F Cuenca, O Greciano, M Gunaratnam, S Haider, D Munnur, R Nanjunda, ...
Bioorganic & medicinal chemistry letters 18 (5), 1668-1673, 2008
A structural analysis of G-quadruplex/ligand interactions
SM Haider, S Neidle, GN Parkinson
Biochimie 93 (8), 1239-1251, 2011
Structure–phenotype correlations of human CYP21A2 mutations in congenital adrenal hyperplasia
S Haider, B Islam, V D’Atri, M Sgobba, C Poojari, L Sun, T Yuen, M Zaidi, ...
Proceedings of the National Academy of Sciences 110 (7), 2605-2610, 2013
A gating mutation at the internal mouth of the Kir6. 2 pore is associated with DEND syndrome
P Proks, C Girard, S Haider, AL Gloyn, AT Hattersley, MSP Sansom, ...
EMBO reports 6 (5), 470-475, 2005
Characterization of a peptide inhibitor of Janus kinase 2 that mimics suppressor of cytokine signaling 1 function
LO Flowers, HM Johnson, MG Mujtaba, MR Ellis, SMI Haider, ...
The Journal of Immunology 172 (12), 7510-7518, 2004
Evaluation of by disubstituted acridone derivatives as telomerase inhibitors: the importance of G-quadruplex binding
RJ Harrison, AP Reszka, SM Haider, B Romagnoli, J Morrell, MA Read, ...
Bioorganic & medicinal chemistry letters 14 (23), 5845-5849, 2004
Rational design of acridine-based ligands with selectivity for human telomeric quadruplexes
S Sparapani, SM Haider, F Doria, M Gunaratnam, S Neidle
Journal of the American Chemical Society 132 (35), 12263-12272, 2010
A G-quadruplex-binding compound showing anti-tumour activity in an in vivo model for pancreatic cancer
SA Ohnmacht, C Marchetti, M Gunaratnam, RJ Besser, SM Haider, ...
Scientific reports 5 (1), 1-11, 2015
Identification of residues contributing to the ATP binding site of Kir6. 2
S Trapp, S Haider, P Jones, MSP Sansom, FM Ashcroft
The EMBO Journal 22 (12), 2903-2912, 2003
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