GEF means go: turning on RHO GTPases with guanine nucleotide-exchange factors KL Rossman, CJ Der, J Sondek Nature reviews Molecular cell biology 6 (2), 167-180, 2005 | 2162 | 2005 |
The Ras superfamily at a glance K Wennerberg, KL Rossman, CJ Der Journal of cell science 118 (5), 843-846, 2005 | 2093 | 2005 |
Increasing complexity of Ras signaling SL Campbell, R Khosravi-Far, KL Rossman, GJ Clark, CJ Der Oncogene 17 (11), 1395-1413, 1998 | 1476 | 1998 |
RAS isoforms and mutations in cancer at a glance GA Hobbs, CJ Der, KL Rossman Journal of cell science 129 (7), 1287-1292, 2016 | 986 | 2016 |
Ras superfamily GEFs and GAPs: validated and tractable targets for cancer therapy? D Vigil, J Cherfils, KL Rossman, CJ Der Nature Reviews Cancer 10 (12), 842-857, 2010 | 977 | 2010 |
Signaling interplay in Ras superfamily function N Mitin, KL Rossman, CJ Der Current Biology 15 (14), R563-R574, 2005 | 535 | 2005 |
Crystal structure of Rac1 in complex with the guanine nucleotide exchange region of Tiam1 DK Worthylake, KL Rossman, J Sondek Nature 408 (6813), 682-688, 2000 | 498 | 2000 |
Dbl family proteins IP Whitehead, S Campbell, KL Rossman, CJ Der Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1332 (1), F1-F23, 1997 | 483 | 1997 |
Rho family proteins and Ras transformation: the RHOad less traveled gets congested IM Zohn, SL Campbell, R Khosravi-Far, KL Rossman, CJ Der Oncogene 17 (11), 1415-1438, 1998 | 455 | 1998 |
Rho guanine nucleotide exchange factors: regulators of Rho GTPase activity in development and disease DR Cook, KL Rossman, CJ Der Oncogene 33 (31), 4021-4035, 2014 | 446 | 2014 |
Vav2 is an activator of Cdc42, Rac1, and RhoA K Abe, KL Rossman, B Liu, KD Ritola, D Chiang, SL Campbell, K Burridge, ... Journal of Biological Chemistry 275 (14), 10141-10149, 2000 | 355 | 2000 |
A crystallographic view of interactions between Dbs and Cdc42: PH domain-assisted guanine nucleotide exchange KL Rossman, DK Worthylake, JT Snyder, DP Siderovski, SL Campbell, ... The EMBO journal 21 (6), 1315-1326, 2002 | 305 | 2002 |
Structural basis for the selective activation of Rho GTPases by Dbl exchange factors JT Snyder, DK Worthylake, KL Rossman, L Betts, WM Pruitt, ... Nature structural biology 9 (6), 468-475, 2002 | 294 | 2002 |
Effects and aftereffects of ibogaine on morphine self-administration in rats. CJN Glick SD, Rossman K, Steindorf S, Maisonneuve IM Eur J Pharmacol. 1991 Apr 3;195(3):341-5119 195 (3), 341-5119, 1991 | 260* | 1991 |
Increasing complexity of Ras signal transduction: involvement of Rho family proteins R Khosravi-Far, S Campbell, KL Rossman, CJ Der Advances in cancer research 72, 57-107, 1997 | 250 | 1997 |
Tuba, a novel protein containing bin/amphiphysin/Rvs and Dbl homology domains, links dynamin to regulation of the actin cytoskeleton MA Salazar, AV Kwiatkowski, L Pellegrini, G Cestra, MH Butler, ... Journal of Biological Chemistry 278 (49), 49031-49043, 2003 | 209 | 2003 |
14-3-3 ζ negatively regulates Raf-1 activity by interactions with the Raf-1 cysteine-rich domain GJ Clark, JK Drugan, KL Rossman, JW Carpenter, K Rogers-Graham, ... Journal of Biological Chemistry 272 (34), 20990-20993, 1997 | 176 | 1997 |
Effects of ibogaine on acute signs of morphine withdrawal in rats: independence from tremor CJN Glick SD, Rossman K, Rao NC, Maisonneuve IM Neuropharmacology 5, 497-500, 1992 | 166* | 1992 |
PH domain of ELMO functions in trans to regulate Rac activation via Dock180 M Lu, JM Kinchen, KL Rossman, C Grimsley, C DeBakker, E Brugnera, ... Nature structural & molecular biology 11 (8), 756-762, 2004 | 150 | 2004 |
Dependence of Dbl and Dbs transformation on MEK and NF-κB activation IP Whitehead, QT Lambert, JA Glaven, K Abe, KL Rossman, GM Mahon, ... Molecular and cellular biology 19 (11), 7759-7770, 1999 | 147 | 1999 |